Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Tubulin beta-9 chain

Gene

TUBB9

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

Miscellaneous

There are nine genes coding for beta-tubulin.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi140 – 146GTPSequence analysis7

GO - Molecular functioni

  • GTPase activity Source: InterPro
  • GTP binding Source: UniProtKB-KW
  • mRNA binding Source: TAIR
  • structural constituent of cytoskeleton Source: InterPro

GO - Biological processi

  • microtubule-based process Source: InterPro
  • response to cadmium ion Source: TAIR

Keywordsi

LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-ATH-5617833 Cilium Assembly
R-ATH-6798695 Neutrophil degranulation
R-ATH-6811434 COPI-dependent Golgi-to-ER retrograde traffic
R-ATH-983189 Kinesins

Names & Taxonomyi

Protein namesi
Recommended name:
Tubulin beta-9 chain
Alternative name(s):
Beta-9-tubulin
Gene namesi
Name:TUBB9
Synonyms:TUB9
Ordered Locus Names:At4g20890
ORF Names:T13K14.50
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G20890
TAIRilocus:2133084 AT4G20890

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Microtubule

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000483281 – 444Tubulin beta-9 chainAdd BLAST444

Proteomic databases

PaxDbiP29517
PRIDEiP29517

Expressioni

Gene expression databases

ExpressionAtlasiP29517 baseline and differential
GenevisibleiP29517 AT

Interactioni

Subunit structurei

Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells. Interacts with TFCA.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
TFCAO043505EBI-2000198,EBI-1999365

Protein-protein interaction databases

BioGridi13128, 7 interactors
IntActiP29517, 2 interactors
MINTiP29517
STRINGi3702.AT4G20890.1

Structurei

3D structure databases

ProteinModelPortaliP29517
SMRiP29517
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tubulin family.Curated

Phylogenomic databases

eggNOGiKOG1375 Eukaryota
COG5023 LUCA
HOGENOMiHOG000165710
InParanoidiP29517
KOiK07375
OMAiCGETDLQ
OrthoDBiEOG093609OI
PhylomeDBiP29517

Family and domain databases

Gene3Di1.10.287.600, 1 hit
3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
InterProiView protein in InterPro
IPR013838 Beta-tubulin_BS
IPR002453 Beta_tubulin
IPR008280 Tub_FtsZ_C
IPR000217 Tubulin
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR023123 Tubulin_C
IPR017975 Tubulin_CS
IPR003008 Tubulin_FtsZ_GTPase
PANTHERiPTHR11588 PTHR11588, 1 hit
PfamiView protein in Pfam
PF00091 Tubulin, 1 hit
PF03953 Tubulin_C, 1 hit
PRINTSiPR01163 BETATUBULIN
PR01161 TUBULIN
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
PROSITEiView protein in PROSITE
PS00227 TUBULIN, 1 hit
PS00228 TUBULIN_B_AUTOREG, 1 hit

Sequencei

Sequence statusi: Complete.

P29517-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MREILHIQGG QCGNQIGAKF WEVICGEHGI DQTGQSCGDT DLQLERINVY
60 70 80 90 100
FNEASGGKYV PRAVLMDLEP GTMDSLRSGP FGQIFRPDNF VFGQSGAGNN
110 120 130 140 150
WAKGHYTEGA ELIDSVLDVV RKEAENCDCL QGFQVCHSLG GGTGSGMGTL
160 170 180 190 200
LISKIREEYP DRMMMTFSVF PSPKVSDTVV EPYNATLSVH QLVENADECM
210 220 230 240 250
VLDNEALYDI CFRTLKLANP TFGDLNHLIS ATMSGVTCCL RFPGQLNSDL
260 270 280 290 300
RKLAVNLIPF PRLHFFMVGF APLTSRGSQQ YSALSVPELT QQMWDAKNMM
310 320 330 340 350
CAADPRHGRY LTASAVFRGK MSTKEVDEQM MNVQNKNSSY FVEWIPNNVK
360 370 380 390 400
SSVCDIAPTG LKMASTFIGN STSIQEMFRR VSEQFTAMFR RKAFLHWYTG
410 420 430 440
EGMDEMEFTE AESNMNDLVA EYQQYQDATV GEEEYEEDEE EEEA
Length:444
Mass (Da):49,658
Last modified:April 1, 1993 - v1
Checksum:i7B67142E86F07C46
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M84706 Genomic DNA Translation: AAA32887.1
AL080282 Genomic DNA Translation: CAB45884.1
AL161553 Genomic DNA Translation: CAB79089.1
CP002687 Genomic DNA Translation: AEE84372.1
AY128337 mRNA Translation: AAM91540.1
AY087594 mRNA Translation: AAM65136.1
PIRiJQ1593
RefSeqiNP_193821.1, NM_118207.3
UniGeneiAt.28063

Genome annotation databases

EnsemblPlantsiAT4G20890.1; AT4G20890.1; AT4G20890
GeneIDi827837
GrameneiAT4G20890.1; AT4G20890.1; AT4G20890
KEGGiath:AT4G20890

Similar proteinsi

Entry informationi

Entry nameiTBB9_ARATH
AccessioniPrimary (citable) accession number: P29517
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: April 1, 1993
Last modified: April 25, 2018
This is version 151 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health