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P29507

- DHE4_SCHOC

UniProt

P29507 - DHE4_SCHOC

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Protein
NADP-specific glutamate dehydrogenase
Gene
GDHA
Organism
Schwanniomyces occidentalis (Yeast) (Debaryomyces occidentalis)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei116 – 1161 By similarity

GO - Molecular functioni

  1. glutamate dehydrogenase (NADP+) activity Source: UniProtKB-EC

GO - Biological processi

  1. cellular amino acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NADP

Names & Taxonomyi

Protein namesi
Recommended name:
NADP-specific glutamate dehydrogenase (EC:1.4.1.4)
Short name:
NADP-GDH
Alternative name(s):
NADP-dependent glutamate dehydrogenase
Gene namesi
Name:GDHA
OrganismiSchwanniomyces occidentalis (Yeast) (Debaryomyces occidentalis)
Taxonomic identifieri27300 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeSchwanniomyces

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 459459NADP-specific glutamate dehydrogenase
PRO_0000182796Add
BLAST

Interactioni

Subunit structurei

Homohexamer By similarity.

Structurei

3D structure databases

ProteinModelPortaliP29507.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR006095. Glu/Leu/Phe/Val_DH.
IPR006096. Glu/Leu/Phe/Val_DH_C.
IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
IPR014362. Glu_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00208. ELFV_dehydrog. 1 hit.
PF02812. ELFV_dehydrog_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000185. Glu_DH. 1 hit.
PRINTSiPR00082. GLFDHDRGNASE.
SMARTiSM00839. ELFV_dehydrog. 1 hit.
[Graphical view]
PROSITEiPS00074. GLFV_DEHYDROGENASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P29507-1 [UniParc]FASTAAdd to Basket

« Hide

MIKNGLPHEP EFQQAYNELV SALEESTLFT EKPEYKKVIP VVSIPERIIQ    50
FRVAWENDNG DVEVNNGFRV QFNSSLGPYK GGLRFHPSVN LSILKFLGFE 100
QIFKNALTGL SMGGGKGGCD FNPKGRSDGE IRRFCVAFMR QLARYIGADT 150
DVPAGDIGVG GREIGYLFGA YKQMQNNWYG VLTGKGLTWG GSLIRPEATG 200
YVSFTTLKKM IEKATNGKES FKGKRVELSG SGNVAQYAAL KVIELGGIVV 250
SLSDSKGSIV SKNGIVPEQV LEIAAAKLKF KSLEEITKES VKLFSGENSV 300
EYLAGVRPWA KVGHFDVALP SATQKEVSGE EEAKALVEAG CKYIAEGSNM 350
GSTKEAIDVF EANRSNNVWY APGKAANCGG VAVSGLEMAQ NSQRVQWSAE 400
EVDAKLKNIM YTCFDNCYDP AIKYSAEKNA DGLPSLLKGA NIASFIKVAD 450
AMFDQGDVY 459
Length:459
Mass (Da):49,831
Last modified:April 1, 1993 - v1
Checksum:i03047D3D1C05B79C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
S64476 Genomic DNA. Translation: AAB20267.1.
PIRiS17907.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
S64476 Genomic DNA. Translation: AAB20267.1 .
PIRi S17907.

3D structure databases

ProteinModelPortali P29507.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
InterProi IPR006095. Glu/Leu/Phe/Val_DH.
IPR006096. Glu/Leu/Phe/Val_DH_C.
IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
IPR014362. Glu_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF00208. ELFV_dehydrog. 1 hit.
PF02812. ELFV_dehydrog_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000185. Glu_DH. 1 hit.
PRINTSi PR00082. GLFDHDRGNASE.
SMARTi SM00839. ELFV_dehydrog. 1 hit.
[Graphical view ]
PROSITEi PS00074. GLFV_DEHYDROGENASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning, sequencing and expression of the Schwanniomyces occidentalis NADP-dependent glutamate dehydrogenase gene."
    de Zoysa P.A., Connerton I.F., Watson D.C., Johnston J.R.
    Curr. Genet. 20:219-224(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiDHE4_SCHOC
AccessioniPrimary (citable) accession number: P29507
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: April 1, 1993
Last modified: October 16, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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