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Reviewed, UniProtKB/Swiss-Prot P29434 (DNAA_BUCAP)

Last modified November 24, 2009. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Chromosomal replication initiator protein dnaA
Gene names
Name: dnaA
Ordered Locus Names: BUsg_012
OrganismBuchnera aphidicola subsp. Schizaphis graminum [Complete proteome] [HAMAP]
Taxonomic identifier98794 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

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Protein attributes

Sequence length454 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the dnaA family.

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 454454Chromosomal replication initiator protein dnaA HAMAP MF_00377
PRO_0000114149

Regions

Nucleotide binding159 – 1668ATP Potential

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Sequences

Sequence LengthMass (Da)Tools
P29434-1 [UniParc].

Last modified April 1, 1993. Version 1.
Checksum: A989508297256C3C

FASTA45452,527
        10         20         30         40         50         60 
MSLCLWKQCL DRLQSELPST EFSMWIRSLK AKLNNNILEI YAPNQFILDW VKDKYLIHFK 

        70         80         90        100        110        120 
KILQDFCGSN SPFIKFKVYQ TSKEKKFKKN ILQKIQNLNA KPIWDKIPIF KKSSHRSNIN 

       130        140        150        160        170        180 
KKHSFENFIE GKSNQLARAA ASQVAKNPGN SYNPLFLYGG TGLGKTHLLH AIGNGILAYK 

       190        200        210        220        230        240 
YNVKIIYMHS ERFVQDMVKA LQNNAIEKFK LYYRSVDALL IDDIQFFAHK ERSQEEFFHT 

       250        260        270        280        290        300 
FNALLEGNQQ IILTSDRYPK EINGVEDRLK SRFGWGLTVA IDPPELETRV AILIKKADEN 

       310        320        330        340        350        360 
NIVLSDEVAF FIAKHLRSNV RELEGALNRV IVNANFTHRS ITVEFVREAL RDILALQEKL 

       370        380        390        400        410        420 
VTIANIQKTV AEYYKIKVAD LLSRRRSRSV ARPRQMAMAM AKELTNHSLP EIGDAFSGRD 

       430        440        450 
HTTVLHACRK IEQLRKENHD IKEDFSNLIR TLSV

« Hide

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References

« Hide 'large scale' references
[1]"Genetic analysis of an aphid endosymbiont DNA fragment homologous to the rnpA-rpmH-dnaA-dnaN-gyrB region of eubacteria."
Lai C.-Y., Baumann P.
Gene 113:175-181(1992) [PubMed: 1572539] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Sequence analysis of a 34.7-kb DNA segment from the genome of Buchnera aphidicola (endosymbiont of aphids) containing groEL, dnaA, the atp operon, gidA, and rho."
Clark M.A., Baumann L., Baumann P.
Curr. Microbiol. 36:158-163(1998) [PubMed: 9516544] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]"50 million years of genomic stasis in endosymbiotic bacteria."
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.
Science 296:2376-2379(2002) [PubMed: 12089438] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

M80817 Genomic DNA. Translation: AAA73149.1. Sequence problems.
AF008210 Genomic DNA. Translation: AAC38106.1.
AE013218 Genomic DNA. Translation: AAM67584.1.
PIRIQJVBA. JC1158.
RefSeqNP_660373.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID1005828.
GenomeReviewsGene locus BUsg_012 in contig AE013218_GR.
KEGGbas:BUsg012.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMP29434.
OMALMETETK

Enzyme and pathway databases

BioCycBAPH198804:BUSG012-MON.

Family and domain databases

HAMAPMF_00377.
[Tree]
InterProIPR003593. ATPase_AAA+_core.
IPR001957. Chromosome_initiator_DnaA.
IPR020591. Chromosome_initiator_DnaA-like.
IPR018312. Chromosome_initiator_DnaA_CS.
IPR013159. DnaA_C.
IPR013317. DnaA_Hda.
IPR010921. Trp_repressor/repl_initiator.
[Graphical view]
PfamPF00308. Bac_DnaA. 1 hit.
PF08299. Bac_DnaA_C. 1 hit.
[Graphical view]
PRINTSPR00051. DNAA.
SMARTSM00382. AAA. 1 hit.
SM00760. Bac_DnaA_C. 1 hit.
[Graphical view]
TIGRFAMsTIGR00362. DnaA. 1 hit.
PROSITEPS01008. DNAA. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameDNAA_BUCAP
AccessionPrimary (citable) accession number: P29434
Entry history
Integrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: April 1, 1993
Last modified: November 24, 2009
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

Buchnera aphidicola (subsp. Schizaphis graminum)

Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents