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P29431 (YIDC_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Membrane protein insertase YidC
Alternative name(s):
Foldase YidC
Membrane integrase YidC
Membrane protein YidC
Gene names
Name:yidC
Ordered Locus Names:BUsg_016
OrganismBuchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]
Taxonomic identifier198804 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length536 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins By similarity.

Subunit structure

Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration By similarity.

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP MF_01810.

Sequence similarities

Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.

Sequence caution

The sequence AAM67588.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Ontologies

Keywords
   Biological processProtein transport
Transport
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionChaperone
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processprotein insertion into membrane

Inferred from electronic annotation. Source: InterPro

   Cellular componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 536536Membrane protein insertase YidC
PRO_0000124697

Regions

Transmembrane7 – 2721Helical; Potential
Transmembrane338 – 35821Helical; Potential
Transmembrane419 – 43921Helical; Potential
Transmembrane453 – 47321Helical; Potential
Transmembrane494 – 51421Helical; Potential

Experimental info

Sequence conflict3671L → V in BAA12844. Ref.1
Sequence conflict3671L → V in AAC38102. Ref.2

Sequences

Sequence LengthMass (Da)Tools
P29431 [UniParc].

Last modified August 30, 2002. Version 3.
Checksum: 27A7C397679D7707

FASTA53662,660
        10         20         30         40         50         60 
MELQRNFFIF AFLFVSFLLW QAWQSQSLKK NKKNEETNSF FHLNHKKEDK NQIIIKNDVL 

        70         80         90        100        110        120 
RLVINMYGGD IEEASLLDYK TQLNSPENLK LLETKSDFVY QAQSGLIGKD GLDNSINKIR 

       130        140        150        160        170        180 
PLYSAKKNFF ELGHNEKELR VPITFIAKNG ITYIKNFILK PGKYNVEVEY DINNLSNKKL 

       190        200        210        220        230        240 
ELNIFGQLKQ TVKLPKNRDI YSGNFALQTF RGAAYSSSDA KYEKYKFDNI ANHEHLHIIT 

       250        260        270        280        290        300 
HHGWIAMLQQ YFVVAWVPDT NISSSNIIYT SYLDNDGIAI IGYKSSLINI PSNSRYIIKS 

       310        320        330        340        350        360 
KLWIGPEKQQ EMALVAPNLD LTVDYGFLWF LSQPLFKLLS TIHNFIGNWG FSIILITFMM 

       370        380        390        400        410        420 
KAITYPLTKA QYTSMSKMRE LQPKINELKK NFGHDKQRMS KEIMALYKKE KINPLGGCLP 

       430        440        450        460        470        480 
VFIQMPIFLS LYYMLIGSVE LRHAPFLFWI KDLSDQDPYY VLPIFMGLTM FFIQRTSSNN 

       490        500        510        520        530 
ISDPFQQKIM HFMPFIFTVF FLWFPSGLVL YYIVSNLVTI IQQKYILSNF KKNQKR 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of 60K, tdhF, groES and groEL genes of Buchnera aphidicola."
Anwarul H.K., Moriya S., Baumann P., Yoshikawa H., Ogasawara N.
Submitted (JUN-1996) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Sequence analysis of a 34.7-kb DNA segment from the genome of Buchnera aphidicola (endosymbiont of aphids) containing groEL, dnaA, the atp operon, gidA, and rho."
Clark M.A., Baumann L., Baumann P.
Curr. Microbiol. 36:158-163(1998) [PubMed: 9516544] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]"50 million years of genomic stasis in endosymbiotic bacteria."
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.
Science 296:2376-2379(2002) [PubMed: 12089438] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sg.
[4]"Genetic analysis of an aphid endosymbiont DNA fragment homologous to the rnpA-rpmH-dnaA-dnaN-gyrB region of eubacteria."
Lai C.-Y., Baumann P.
Gene 113:175-181(1992) [PubMed: 1572539] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-273.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D85628 Genomic DNA. Translation: BAA12844.1.
AF008210 Genomic DNA. Translation: AAC38102.1.
AE013218 Genomic DNA. Translation: AAM67588.1. Different initiation.
M80817 Genomic DNA. Translation: AAA73145.1.
PIRJC1157.
RefSeqNP_660377.1. NC_004061.1.

3D structure databases

ProteinModelPortalP29431.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBUCT00000000398; EBBUCP00000000398; EBBUCG00000000398.
GeneID1005832.
GenomeReviewsGene locus BUsg_016 in contig AE013218_GR.
KEGGbas:BUsg016.
PATRIC21246787. VBIBucAph100086_0016.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000007702.
HOGENOMHBG507812.
OMATYRGAAF.
ProtClustDBCLSK315002.

Enzyme and pathway databases

BioCycBAPH198804:BUSG016-MONOMER.

Family and domain databases

HAMAPMF_01810. YidC_type1.
[Tree]
InterProIPR019998. Membr_insert_OxaA/YidC_bac.
IPR001708. Membrane_insertion_OxaA/YidC.
[Graphical view]
KOK03217.
PANTHERPTHR12428. Innermemb_insert. 1 hit.
PfamPF02096. 60KD_IMP. 1 hit.
[Graphical view]
PRINTSPR00701. 60KDINNERMP.
PR01900. YIDCPROTEIN.
TIGRFAMsTIGR03593. YidC_nterm. 1 hit.
TIGR03592. YidC_oxa1_C. 1 hit.
ProtoNetSearch...

Entry information

Entry nameYIDC_BUCAP
AccessionPrimary (citable) accession number: P29431
Entry history
Integrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: August 30, 2002
Last modified: January 25, 2012
This is version 75 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Buchnera aphidicola (subsp. Schizaphis graminum)

Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names

SIMILARITY comments

Index of protein domains and families