Reviewed, UniProtKB/Swiss-Prot P29431 (OXAA_BUCAP)

Names and origin

Protein names

Recommended name:
    Membrane protein oxaA

Gene names

Name:	oxaA
Ordered Locus Names:	BUsg_016

Organism

Buchnera aphidicola subsp. Schizaphis graminum [Complete proteome] [HAMAP]

Taxonomic identifier

98794 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	536 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and independently of the Sec translocase complex By similarity.
Subunit structure	Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration By similarity.
Subcellular location	Cell membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the OXA1/oxaA family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein insertion into membrane Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 536	536	Membrane protein oxaA HAMAP MF_01810		PRO_0000124697
Regions
	Transmembrane	7 – 24	18	Potential
	Transmembrane	345 – 367	23	Potential
	Transmembrane	414 – 436	23	Potential
	Transmembrane	492 – 514	23	Potential
Experimental info
	Sequence conflict	367	1	L → V Ref.1
	Sequence conflict	367	1	L → V Ref.2

Sequences

	Sequence		Length	Mass (Da)
	P29431-1 [UniParc]. Last modified August 30, 2002. Version 3. Checksum: 27A7C397679D7707	FASTA	536	62,660
	10 20 30 40 50 60 MELQRNFFIF AFLFVSFLLW QAWQSQSLKK NKKNEETNSF FHLNHKKEDK NQIIIKNDVL 70 80 90 100 110 120 RLVINMYGGD IEEASLLDYK TQLNSPENLK LLETKSDFVY QAQSGLIGKD GLDNSINKIR 130 140 150 160 170 180 PLYSAKKNFF ELGHNEKELR VPITFIAKNG ITYIKNFILK PGKYNVEVEY DINNLSNKKL 190 200 210 220 230 240 ELNIFGQLKQ TVKLPKNRDI YSGNFALQTF RGAAYSSSDA KYEKYKFDNI ANHEHLHIIT 250 260 270 280 290 300 HHGWIAMLQQ YFVVAWVPDT NISSSNIIYT SYLDNDGIAI IGYKSSLINI PSNSRYIIKS 310 320 330 340 350 360 KLWIGPEKQQ EMALVAPNLD LTVDYGFLWF LSQPLFKLLS TIHNFIGNWG FSIILITFMM 370 380 390 400 410 420 KAITYPLTKA QYTSMSKMRE LQPKINELKK NFGHDKQRMS KEIMALYKKE KINPLGGCLP 430 440 450 460 470 480 VFIQMPIFLS LYYMLIGSVE LRHAPFLFWI KDLSDQDPYY VLPIFMGLTM FFIQRTSSNN 490 500 510 520 530 ISDPFQQKIM HFMPFIFTVF FLWFPSGLVL YYIVSNLVTI IQQKYILSNF KKNQKR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of 60K, tdhF, groES and groEL genes of Buchnera aphidicola." Anwarul H.K., Moriya S., Baumann P., Yoshikawa H., Ogasawara N. Submitted (JUN-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Sequence analysis of a 34.7-kb DNA segment from the genome of Buchnera aphidicola (endosymbiont of aphids) containing groEL, dnaA, the atp operon, gidA, and rho." Clark M.A., Baumann L., Baumann P. Curr. Microbiol. 36:158-163(1998) [PubMed: 9516544] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]	"50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed: 12089438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	"Genetic analysis of an aphid endosymbiont DNA fragment homologous to the rnpA-rpmH-dnaA-dnaN-gyrB region of eubacteria." Lai C.-Y., Baumann P. Gene 113:175-181(1992) [PubMed: 1572539] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-273.

Cross-references

Sequence databases
EMBLGenBankDDBJ	D85628 Genomic DNA. Translation: BAA12844.1. AF008210 Genomic DNA. Translation: AAC38102.1. AE013218 Genomic DNA. Translation: AAM67588.1. Different initiation. M80817 Genomic DNA. Translation: AAA73145.1.
PIR	JC1157.
RefSeq	NP_660377.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1005832.
GenomeReviews	Gene locus BUsg_016 in contig AE013218_GR.
KEGG	bas:BUsg016.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P29431.
OMA	TYRGAAF
Enzyme and pathway databases
BioCyc	BAPH198804:BUSG016-MON.
Family and domain databases
HAMAP	MF_01810. [Tree]
InterPro	IPR020001. Membrane_insert_OxaA/YidC_core. IPR001708. Membrane_insertion_OxaA/YidC. IPR013308. Membrane_insertion_YidC. IPR019998. Membrane_insertion_YidC/OxoA_N. [Graphical view]
PANTHER	PTHR12428. Innermemb_insert. 1 hit.
Pfam	PF02096. 60KD_IMP. 1 hit. [Graphical view]
PRINTS	PR00701. 60KDINNERMP. PR01900. YIDCPROTEIN.
TIGRFAMs	TIGR03593. YidC_nterm. 1 hit. TIGR03592. YidC_oxa1_C. 1 hit.
ProtoNet	Search...

Entry information

Entry name

OXAA_BUCAP

Accession

Primary (citable) accession number: P29431

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1993
Last sequence update:	August 30, 2002
Last modified:	November 24, 2009
This is version 61 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)