Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P29407

- PGK_YARLI

UniProt

P29407 - PGK_YARLI

Protein

Phosphoglycerate kinase

Gene

PGK1

Organism
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (01 Apr 1993)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei39 – 391SubstrateBy similarity
    Binding sitei122 – 1221SubstrateBy similarity
    Binding sitei170 – 1701SubstrateBy similarity
    Binding sitei219 – 2191ATPBy similarity
    Binding sitei312 – 3121ATP; via carbonyl oxygenBy similarity
    Binding sitei343 – 3431ATPBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi372 – 3754ATPBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinase (EC:2.7.2.3)
    Gene namesi
    Name:PGK1
    Ordered Locus Names:YALI0D12400g
    OrganismiYarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
    Taxonomic identifieri284591 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia
    ProteomesiUP000001300: Chromosome D

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 417417Phosphoglycerate kinasePRO_0000145892Add
    BLAST

    Proteomic databases

    PRIDEiP29407.

    Interactioni

    Subunit structurei

    Monomer.By similarity

    Protein-protein interaction databases

    STRINGi4952.P29407.

    Structurei

    3D structure databases

    ProteinModelPortaliP29407.
    SMRiP29407. Positions 2-417.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni24 – 263Substrate bindingBy similarity
    Regioni63 – 664Substrate bindingBy similarity

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.Curated

    Phylogenomic databases

    eggNOGiCOG0126.
    HOGENOMiHOG000227107.
    KOiK00927.
    OrthoDBiEOG71K6D7.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.
    PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P29407-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSLTNKLSIK DLDLKNKRVF IRVDFNVPLD GTTITNNQRI VAALPSIKYA    50
    IDQGAKAVIL ASHLGRPNGQ RVEKYSLKPV QAELSKLLGK PVTFLDDCVG 100
    PKVEEEVSKA KDGEVILLEN LRFHPEEEGS HKDADGKKIK ADPAKVEEFR 150
    KSLTSLADVY VNDAFGTAHR AHSSMVGIEL PQRAAGFLVA KELEFFAKAL 200
    EHPERPFLAI LGGAKVSDKI QLIDNLLDKV NALIIGGGMA FTFKKTLENV 250
    KIGNSLFDED GSKIVAGLVE KAKKNNVKLV FPVDYVTADK FSKDAKVGHA 300
    TDAEGIPDGW QGLDCGPKSI EEFQKVIGES KTILWNGPPG VFEFDNFAKG 350
    TKAVLDACVK AVDNGATVII GGGDTATVAK KYGAEDKLSH VSTGGGASLE 400
    LLEGKTLPGV AALSEKK 417
    Length:417
    Mass (Da):44,772
    Last modified:April 1, 1993 - v1
    Checksum:i3F308467FCC730BF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M91598 Genomic DNA. Translation: AAC37504.1.
    CR382130 Genomic DNA. Translation: CAG80930.1.
    PIRiS68151.
    RefSeqiXP_502742.1. XM_502742.1.

    Genome annotation databases

    EnsemblFungiiCAG80930; CAG80930; YALI0_D12400g.
    GeneIDi2910137.
    KEGGiyli:YALI0D12400g.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M91598 Genomic DNA. Translation: AAC37504.1 .
    CR382130 Genomic DNA. Translation: CAG80930.1 .
    PIRi S68151.
    RefSeqi XP_502742.1. XM_502742.1.

    3D structure databases

    ProteinModelPortali P29407.
    SMRi P29407. Positions 2-417.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 4952.P29407.

    Proteomic databases

    PRIDEi P29407.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CAG80930 ; CAG80930 ; YALI0_D12400g .
    GeneIDi 2910137.
    KEGGi yli:YALI0D12400g.

    Phylogenomic databases

    eggNOGi COG0126.
    HOGENOMi HOG000227107.
    KOi K00927.
    OrthoDBi EOG71K6D7.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The 3-phosphoglycerate kinase gene of the yeast Yarrowia lipolytica de-represses on gluconeogenic substrates."
      le Dall M.-T., Nicaud J.-M., Treton B.Y., Gaillardin C.M.
      Curr. Genet. 29:446-456(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 20460 / W29 / CBS 7504 / IFP29.
    2. "Genome evolution in yeasts."
      Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.
      , Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L.
      Nature 430:35-44(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CLIB 122 / E 150.

    Entry informationi

    Entry nameiPGK_YARLI
    AccessioniPrimary (citable) accession number: P29407
    Secondary accession number(s): Q6C9C0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 1, 1993
    Last sequence update: April 1, 1993
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3