Skip Header

 
Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot P29406 (PGK2_RHINI)

Last modified June 16, 2009. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Hide | Top

Names and origin

Protein namesRecommended name:
    Phosphoglycerate kinase 2
    EC=2.7.2.3
Gene names
Name: PGK2
OrganismRhizopus niveus
Taxonomic identifier4844 [NCBI]
Taxonomic lineageEukaryota › Fungi › Fungi incertae sedis › Basal fungal lineages › Mucoromycotina › Mucorales › Mucoraceae › Rhizopus

Hide | Top

Protein attributes

Sequence length417 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

Hide | Top

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.

Subunit structure

Monomer.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Hide | Top

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
Gene Ontology (GO)
   Biological processglycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Hide | Top

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 417417Phosphoglycerate kinase 2
PRO_0000145888

Regions

Nucleotide binding372 – 3754ATP By similarity
Region24 – 263Substrate binding By similarity
Region63 – 664Substrate binding By similarity

Sites

Binding site391Substrate By similarity
Binding site1221Substrate By similarity
Binding site1691Substrate By similarity
Binding site2181ATP By similarity
Binding site3121ATP; via carbonyl oxygen By similarity
Binding site3431ATP By similarity

Hide | Top

Sequences

Sequence LengthMass (Da)Tools
P29406-1 [UniParc].

Last modified April 1, 1993. Version 1.
Checksum: 45AC26C03CF01776

FASTA41744,656
        10         20         30         40         50         60 
MSLSNKLSIR DLDLKNKRVL IRVDFNVPMK DGAITNNNRI VQALPTVKYA LDNGASAVIL 

        70         80         90        100        110        120 
MSHLGRPNGE AVAKYSLKPV AAEVEKLLGK PVEFLNDCVG PDVEKACQSA TGGKVILLEN 

       130        140        150        160        170        180 
LRFHIEEEGS AKVRWSKVKA DAEAVKKFRA SLTALADIYV NDAFGTAHRA HSSMVGVDLS 

       190        200        210        220        230        240 
QRAAGFLMQK ELEYFAKALE NPARPFLAIL GGAKVSDKIQ LIENMLDKVN ALIVCGGMAF 

       250        260        270        280        290        300 
TFKKTLDNVK QIGKSLFDEA GSKLVRNLVK KAAEKNVKLV FPVDFVTADK FAPDANTGYA 

       310        320        330        340        350        360 
TDADGIPDEW EGLDCGKKSS ELFREEILKS KTIVWNGPSG VFEFDAFANG TKSVLNAVIE 

       370        380        390        400        410 
ATKEGATTII GGGDTATAAL KWGAEGKVSH ISTGGGASLE LLEGKELPGV TALSSKN

« Hide

Hide | Top

References

[1]"Cloning and characterization of two 3-phosphoglycerate kinase genes of Rhizopus niveus and heterologous gene expression using their promoters."
Yanai K., Tanaka N., Horiuchi H., Ohta A., Takagi M.
Curr. Genet. 25:524-530(1994) [PubMed: 8082204] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: IFO 4810 / AS 3.4817.

Hide | Top

Cross-references

Sequence databases

D10156 Genomic DNA. Translation: BAA01020.1.
PIRS44063.

3D structure databases

HSSPHSSP built from PDB template 1QPG based on UniProtKB P00560.
ModBaseSearch...

Enzyme and pathway databases

BRENDA2.7.2.3. 18853.

Family and domain databases

InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.1270. Phosphoglycerate_kinase_C. 1 hit.
G3DSA:3.40.50.1260. Phosphoglycerate_kinase_N. 1 hit.
PANTHERPTHR11406. PGK. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PRINTSPR00477. PHGLYCKINASE.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Hide | Top

Entry information

Entry namePGK2_RHINI
AccessionPrimary (citable) accession number: P29406
Entry history
Integrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: April 1, 1993
Last modified: June 16, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

Hide | Top

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents