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P29406

- PGK2_RHINI

UniProt

P29406 - PGK2_RHINI

Protein

Phosphoglycerate kinase 2

Gene

PGK2

Organism
Rhizopus niveus
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (01 Apr 1993)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei39 – 391SubstrateBy similarity
    Binding sitei122 – 1221SubstrateBy similarity
    Binding sitei169 – 1691SubstrateBy similarity
    Binding sitei218 – 2181ATPBy similarity
    Binding sitei312 – 3121ATP; via carbonyl oxygenBy similarity
    Binding sitei343 – 3431ATPBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi372 – 3754ATPBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinase 2 (EC:2.7.2.3)
    Gene namesi
    Name:PGK2
    OrganismiRhizopus niveus
    Taxonomic identifieri4844 [NCBI]
    Taxonomic lineageiEukaryotaFungiFungi incertae sedisEarly diverging fungal lineagesMucoromycotinaMucoralesMucorineaeRhizopodaceaeRhizopus

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 417417Phosphoglycerate kinase 2PRO_0000145888Add
    BLAST

    Proteomic databases

    PRIDEiP29406.

    Interactioni

    Subunit structurei

    Monomer.

    Structurei

    3D structure databases

    ProteinModelPortaliP29406.
    SMRiP29406. Positions 2-415.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni24 – 263Substrate bindingBy similarity
    Regioni63 – 664Substrate bindingBy similarity

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.Curated

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.
    PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P29406-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSLSNKLSIR DLDLKNKRVL IRVDFNVPMK DGAITNNNRI VQALPTVKYA    50
    LDNGASAVIL MSHLGRPNGE AVAKYSLKPV AAEVEKLLGK PVEFLNDCVG 100
    PDVEKACQSA TGGKVILLEN LRFHIEEEGS AKVRWSKVKA DAEAVKKFRA 150
    SLTALADIYV NDAFGTAHRA HSSMVGVDLS QRAAGFLMQK ELEYFAKALE 200
    NPARPFLAIL GGAKVSDKIQ LIENMLDKVN ALIVCGGMAF TFKKTLDNVK 250
    QIGKSLFDEA GSKLVRNLVK KAAEKNVKLV FPVDFVTADK FAPDANTGYA 300
    TDADGIPDEW EGLDCGKKSS ELFREEILKS KTIVWNGPSG VFEFDAFANG 350
    TKSVLNAVIE ATKEGATTII GGGDTATAAL KWGAEGKVSH ISTGGGASLE 400
    LLEGKELPGV TALSSKN 417
    Length:417
    Mass (Da):44,656
    Last modified:April 1, 1993 - v1
    Checksum:i45AC26C03CF01776
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D10156 Genomic DNA. Translation: BAA01020.1.
    PIRiS44063.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D10156 Genomic DNA. Translation: BAA01020.1 .
    PIRi S44063.

    3D structure databases

    ProteinModelPortali P29406.
    SMRi P29406. Positions 2-415.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi P29406.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and characterization of two 3-phosphoglycerate kinase genes of Rhizopus niveus and heterologous gene expression using their promoters."
      Yanai K., Tanaka N., Horiuchi H., Ohta A., Takagi M.
      Curr. Genet. 25:524-530(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: NBRC 4810 / AS 3.4817.

    Entry informationi

    Entry nameiPGK2_RHINI
    AccessioniPrimary (citable) accession number: P29406
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 1, 1993
    Last sequence update: April 1, 1993
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3