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P29395 (RL11_THEMA) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 114. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
50S ribosomal protein L11
Gene names
Name:rplK
Ordered Locus Names:TM_0454
OrganismThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) [Reference proteome] [HAMAP]
Taxonomic identifier243274 [NCBI]
Taxonomic lineageBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga

Protein attributes

Sequence length141 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. HAMAP-Rule MF_00736

Subunit structure

Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which 3 L12 dimers bind in a sequential fashion forming a heptameric L10(L12)2(L12)2(L12)2 complex.

Post-translational modification

One or more lysine residues are methylated By similarity. HAMAP-Rule MF_00736

Sequence similarities

Belongs to the ribosomal protein L11P family.

Ontologies

Keywords
   LigandRNA-binding
rRNA-binding
   Molecular functionRibonucleoprotein
Ribosomal protein
   PTMMethylation
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentribosome

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionLSU rRNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

structural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 14114050S ribosomal protein L11 HAMAP-Rule MF_00736
PRO_0000104397

Secondary structure

............................ 141
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P29395 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 08AD83D090F651A9

FASTA14115,089
        10         20         30         40         50         60 
MAKKVAAQIK LQLPAGKATP APPVGPALGQ HGVNIMEFCK RFNAETADKA GMILPVVITV 

        70         80         90        100        110        120 
YEDKSFTFII KTPPASFLLK KAAGIEKGSS EPKRKIVGKV TRKQIEEIAK TKMPDLNANS 

       130        140 
LEAAMKIIEG TAKSMGIEVV D 

« Hide

References

« Hide 'large scale' references
[1]"The organization and expression of essential transcription translation component genes in the extremely thermophilic eubacterium Thermotoga maritima."
Liao D., Dennis P.P.
J. Biol. Chem. 267:22787-22797(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
[2]"Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima."
Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A., Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M., Cotton M.D., Pratt M.S. expand/collapse author list , Phillips C.A., Richardson D.L., Heidelberg J.F., Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L., Smith H.O., Venter J.C., Fraser C.M.
Nature 399:323-329(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
[3]"A detailed view of a ribosomal active site: the structure of the L11-RNA complex."
Wimberly B.T., Guymon R., McCutcheon J.P., White S.W., Ramakrishnan V.
Cell 97:491-502(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.57 ANGSTROMS).
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z11839 Genomic DNA. Translation: CAA77859.1.
AE000512 Genomic DNA. Translation: AAD35537.1.
PIRR5HG11. B44466.
RefSeqNP_228264.1. NC_000853.1.
YP_007976801.1. NC_021214.1.
YP_008990576.1. NC_023151.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1IP8model-G-[»]
1JQMelectron microscopy-A2-140[»]
1JQSelectron microscopy-A2-140[»]
1JQTelectron microscopy-A2-140[»]
1MMSX-ray2.57A/B2-141[»]
1MVRelectron microscopy12.80L2-141[»]
1OLNNMR-A2-141[»]
1PN7electron microscopy10.80L8-140[»]
1PN8electron microscopy10.80L8-140[»]
1R2Welectron microscopy9.00A2-141[»]
1R2Xelectron microscopy9.00A2-141[»]
2BCWelectron microscopy11.20A8-72[»]
2GKYmodel-A8-140[»]
2GKZmodel-A8-140[»]
2JQ7NMR-A1-141[»]
2K3FNMR-A1-141[»]
ProteinModelPortalP29395.
SMRP29395. Positions 1-141.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

MINTMINT-208764.
STRING243274.TM0454.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAD35537; AAD35537; TM_0454.
GeneID897484.
KEGGtma:TM0454.
tmi:THEMA_02420.
tmm:Tmari_0451.
PATRIC23935803. VBITheMar51294_0460.

Phylogenomic databases

eggNOGCOG0080.
KOK02867.
OMAANYLHEQ.
OrthoDBEOG69PQ9D.

Family and domain databases

Gene3D1.10.10.250. 1 hit.
3.30.1550.10. 1 hit.
HAMAPMF_00736. Ribosomal_L11.
InterProIPR000911. Ribosomal_L11/L12.
IPR006519. Ribosomal_L11_bac-typ.
IPR020783. Ribosomal_L11_C.
IPR020785. Ribosomal_L11_CS.
IPR020784. Ribosomal_L11_N.
[Graphical view]
PANTHERPTHR11661. PTHR11661. 1 hit.
PfamPF00298. Ribosomal_L11. 1 hit.
PF03946. Ribosomal_L11_N. 1 hit.
[Graphical view]
SMARTSM00649. RL11. 1 hit.
[Graphical view]
SUPFAMSSF46906. SSF46906. 1 hit.
SSF54747. SSF54747. 1 hit.
TIGRFAMsTIGR01632. L11_bact. 1 hit.
PROSITEPS00359. RIBOSOMAL_L11. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP29395.

Entry information

Entry nameRL11_THEMA
AccessionPrimary (citable) accession number: P29395
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: January 23, 2007
Last modified: July 9, 2014
This is version 114 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references