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P29395

- RL11_THEMA

UniProt

P29395 - RL11_THEMA

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Protein

50S ribosomal protein L11

Gene
rplK, TM_0454
Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.UniRule annotation

GO - Molecular functioni

  1. large ribosomal subunit rRNA binding Source: UniProtKB-HAMAP
  2. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L11
Gene namesi
Name:rplK
Ordered Locus Names:TM_0454
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
ProteomesiUP000008183: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. ribosome Source: UniProtKB-KW
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed By similarity
Chaini2 – 14114050S ribosomal protein L11UniRule annotationPRO_0000104397Add
BLAST

Post-translational modificationi

One or more lysine residues are methylated By similarity.UniRule annotation

Keywords - PTMi

Methylation

Interactioni

Subunit structurei

Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which 3 L12 dimers bind in a sequential fashion forming a heptameric L10(L12)2(L12)2(L12)2 complex.

Protein-protein interaction databases

MINTiMINT-208764.
STRINGi243274.TM0454.

Structurei

Secondary structure

1
141
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi9 – 146
Turni21 – 255
Helixi26 – 294
Turni30 – 323
Helixi35 – 4511
Turni46 – 483
Beta strandi51 – 6010
Beta strandi62 – 643
Beta strandi66 – 705
Helixi75 – 839
Turni92 – 943
Beta strandi98 – 1014
Helixi102 – 11211
Helixi113 – 1153
Helixi121 – 13212
Turni133 – 1364
Beta strandi137 – 1404

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1IP8model-G-[»]
1JQMelectron microscopy-A2-140[»]
1JQSelectron microscopy-A2-140[»]
1JQTelectron microscopy-A2-140[»]
1MMSX-ray2.57A/B2-141[»]
1MVRelectron microscopy12.80L2-141[»]
1OLNNMR-A2-141[»]
1PN7electron microscopy10.80L8-140[»]
1PN8electron microscopy10.80L8-140[»]
1R2Welectron microscopy9.00A2-141[»]
1R2Xelectron microscopy9.00A2-141[»]
2BCWelectron microscopy11.20A8-72[»]
2GKYmodel-A8-140[»]
2GKZmodel-A8-140[»]
2JQ7NMR-A1-141[»]
2K3FNMR-A1-141[»]
ProteinModelPortaliP29395.
SMRiP29395. Positions 1-141.

Miscellaneous databases

EvolutionaryTraceiP29395.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0080.
KOiK02867.
OMAiANYLHEQ.
OrthoDBiEOG69PQ9D.

Family and domain databases

Gene3Di1.10.10.250. 1 hit.
3.30.1550.10. 1 hit.
HAMAPiMF_00736. Ribosomal_L11.
InterProiIPR000911. Ribosomal_L11/L12.
IPR006519. Ribosomal_L11_bac-typ.
IPR020783. Ribosomal_L11_C.
IPR020785. Ribosomal_L11_CS.
IPR020784. Ribosomal_L11_N.
[Graphical view]
PANTHERiPTHR11661. PTHR11661. 1 hit.
PfamiPF00298. Ribosomal_L11. 1 hit.
PF03946. Ribosomal_L11_N. 1 hit.
[Graphical view]
SMARTiSM00649. RL11. 1 hit.
[Graphical view]
SUPFAMiSSF46906. SSF46906. 1 hit.
SSF54747. SSF54747. 1 hit.
TIGRFAMsiTIGR01632. L11_bact. 1 hit.
PROSITEiPS00359. RIBOSOMAL_L11. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P29395-1 [UniParc]FASTAAdd to Basket

« Hide

MAKKVAAQIK LQLPAGKATP APPVGPALGQ HGVNIMEFCK RFNAETADKA    50
GMILPVVITV YEDKSFTFII KTPPASFLLK KAAGIEKGSS EPKRKIVGKV 100
TRKQIEEIAK TKMPDLNANS LEAAMKIIEG TAKSMGIEVV D 141
Length:141
Mass (Da):15,089
Last modified:January 23, 2007 - v3
Checksum:i08AD83D090F651A9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z11839 Genomic DNA. Translation: CAA77859.1.
AE000512 Genomic DNA. Translation: AAD35537.1.
PIRiB44466. R5HG11.
RefSeqiNP_228264.1. NC_000853.1.
YP_007976801.1. NC_021214.1.
YP_008990576.1. NC_023151.1.

Genome annotation databases

EnsemblBacteriaiAAD35537; AAD35537; TM_0454.
GeneIDi897484.
KEGGitma:TM0454.
tmi:THEMA_02420.
tmm:Tmari_0451.
PATRICi23935803. VBITheMar51294_0460.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z11839 Genomic DNA. Translation: CAA77859.1 .
AE000512 Genomic DNA. Translation: AAD35537.1 .
PIRi B44466. R5HG11.
RefSeqi NP_228264.1. NC_000853.1.
YP_007976801.1. NC_021214.1.
YP_008990576.1. NC_023151.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1IP8 model - G - [» ]
1JQM electron microscopy - A 2-140 [» ]
1JQS electron microscopy - A 2-140 [» ]
1JQT electron microscopy - A 2-140 [» ]
1MMS X-ray 2.57 A/B 2-141 [» ]
1MVR electron microscopy 12.80 L 2-141 [» ]
1OLN NMR - A 2-141 [» ]
1PN7 electron microscopy 10.80 L 8-140 [» ]
1PN8 electron microscopy 10.80 L 8-140 [» ]
1R2W electron microscopy 9.00 A 2-141 [» ]
1R2X electron microscopy 9.00 A 2-141 [» ]
2BCW electron microscopy 11.20 A 8-72 [» ]
2GKY model - A 8-140 [» ]
2GKZ model - A 8-140 [» ]
2JQ7 NMR - A 1-141 [» ]
2K3F NMR - A 1-141 [» ]
ProteinModelPortali P29395.
SMRi P29395. Positions 1-141.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

MINTi MINT-208764.
STRINGi 243274.TM0454.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD35537 ; AAD35537 ; TM_0454 .
GeneIDi 897484.
KEGGi tma:TM0454.
tmi:THEMA_02420.
tmm:Tmari_0451.
PATRICi 23935803. VBITheMar51294_0460.

Phylogenomic databases

eggNOGi COG0080.
KOi K02867.
OMAi ANYLHEQ.
OrthoDBi EOG69PQ9D.

Miscellaneous databases

EvolutionaryTracei P29395.

Family and domain databases

Gene3Di 1.10.10.250. 1 hit.
3.30.1550.10. 1 hit.
HAMAPi MF_00736. Ribosomal_L11.
InterProi IPR000911. Ribosomal_L11/L12.
IPR006519. Ribosomal_L11_bac-typ.
IPR020783. Ribosomal_L11_C.
IPR020785. Ribosomal_L11_CS.
IPR020784. Ribosomal_L11_N.
[Graphical view ]
PANTHERi PTHR11661. PTHR11661. 1 hit.
Pfami PF00298. Ribosomal_L11. 1 hit.
PF03946. Ribosomal_L11_N. 1 hit.
[Graphical view ]
SMARTi SM00649. RL11. 1 hit.
[Graphical view ]
SUPFAMi SSF46906. SSF46906. 1 hit.
SSF54747. SSF54747. 1 hit.
TIGRFAMsi TIGR01632. L11_bact. 1 hit.
PROSITEi PS00359. RIBOSOMAL_L11. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The organization and expression of essential transcription translation component genes in the extremely thermophilic eubacterium Thermotoga maritima."
    Liao D., Dennis P.P.
    J. Biol. Chem. 267:22787-22797(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
  3. "A detailed view of a ribosomal active site: the structure of the L11-RNA complex."
    Wimberly B.T., Guymon R., McCutcheon J.P., White S.W., Ramakrishnan V.
    Cell 97:491-502(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.57 ANGSTROMS).

Entry informationi

Entry nameiRL11_THEMA
AccessioniPrimary (citable) accession number: P29395
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: January 23, 2007
Last modified: July 9, 2014
This is version 114 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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