Reviewed, UniProtKB/Swiss-Prot P29395 (RL11_THEMA)

Names and origin

Protein names

Recommended name:
    50S ribosomal protein L11

Gene names

Name:	rplK
Ordered Locus Names:	TM_0454

Organism

Thermotoga maritima [Complete proteome] [HAMAP]

Taxonomic identifier

2336 [NCBI]

Taxonomic lineage

Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga

Protein attributes

Sequence length	141 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	This protein binds directly to 23S ribosomal RNA. HAMAP MF_00736
Post-translational modification	One or more lysine residues are methylated By similarity.
Sequence similarities	Belongs to the ribosomal protein L11P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
PTM	Methylation
Technical term	3D-structure Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Initiator methionine

1

1

Removed HAMAP MF_00736

Chain

2 – 141

140

50S ribosomal protein L11 HAMAP MF_00736

PRO_0000104397

Secondary structure

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141

Helix Strand Turn

Details...

Beta strand

9 – 14

6

Turn

21 – 25

5

Helix

26 – 29

4

Turn

30 – 32

3

Helix

35 – 45

11

Turn

46 – 48

3

Beta strand

51 – 60

10

Beta strand

66 – 70

5

Helix

75 – 83

9

Turn

92 – 94

3

Beta strand

98 – 101

4

Helix

102 – 112

11

Helix

113 – 115

3

Helix

121 – 132

12

Turn

133 – 136

4

Beta strand

137 – 140

4

Sequences

	Sequence		Length	Mass (Da)
	P29395-1 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: 08AD83D090F651A9	FASTA	141	15,089
	10 20 30 40 50 60 MAKKVAAQIK LQLPAGKATP APPVGPALGQ HGVNIMEFCK RFNAETADKA GMILPVVITV 70 80 90 100 110 120 YEDKSFTFII KTPPASFLLK KAAGIEKGSS EPKRKIVGKV TRKQIEEIAK TKMPDLNANS 130 140 LEAAMKIIEG TAKSMGIEVV D

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The organization and expression of essential transcription translation component genes in the extremely thermophilic eubacterium Thermotoga maritima." Liao D., Dennis P.P. J. Biol. Chem. 267:22787-22797(1992) [PubMed: 1429627] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
[2]	"Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima." Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A., Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M., Cotton M.D., Pratt M.S. , Phillips C.A., Richardson D.L., Heidelberg J.F., Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L., Smith H.O., Venter J.C., Fraser C.M. Nature 399:323-329(1999) [PubMed: 10360571] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
[3]	"A detailed view of a ribosomal active site: the structure of the L11-RNA complex." Wimberly B.T., Guymon R., McCutcheon J.P., White S.W., Ramakrishnan V. Cell 97:491-502(1999) [PubMed: 10338213] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.57 ANGSTROMS).
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBLGenBankDDBJ

Z11839 Genomic DNA. Translation: CAA77859.1.
AE000512 Genomic DNA. Translation: AAD35537.1.

PIR

R5HG11. B44466.

RefSeq

NP_228264.1.

3D structure databases

PDBPDBe

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1EG0	electron microscopy	11.50	K	1-140	[»]
1IP8	model	-	G	-	[»]
1JQM	electron microscopy	-	A	2-139	[»]
1JQS	electron microscopy	-	A	2-139	[»]
1JQT	electron microscopy	-	A	2-139	[»]
1MMS	X-ray	2.57	A/B	2-141	[»]
1MVR	electron microscopy	12.80	L	2-140	[»]
1OLN	NMR	-	A	2-141	[»]
1PN7	electron microscopy	10.80	L	8-139	[»]
1PN8	electron microscopy	10.80	L	8-139	[»]
1R2W	electron microscopy	9.00	A	2-140	[»]
1R2X	electron microscopy	9.00	A	2-140	[»]
2B66	X-ray	5.90	K	1-141	[»]
2B9N	X-ray	6.76	K	1-141	[»]
2B9P	X-ray	6.46	K	1-141	[»]
2BCW	electron microscopy	11.20	A	8-71	[»]
2GKY	model	-	A	8-140	[»]
2GKZ	model	-	A	8-140	[»]
2JQ7	NMR	-	A	1-141	[»]
2K3F	NMR	-	A	1-141	[»]

ModBase

Search...

Genome annotation databases

GeneID

897484.

GenomeReviews

Gene locus TM_0454 in contig AE000512_GR.

KEGG

tma:TM0454.

NMPDR

fig|243274.1.peg.448.

TIGR

TM_0454.

Phylogenomic databases

HOGENOM

P29395.

OMA

MGLQVEG.

Enzyme and pathway databases

BioCyc

TMAR243274:TM_0454-MON.

Family and domain databases

HAMAP

MF_00736.
[Tree]

InterPro

IPR000911. Ribosomal_L11.
IPR006519. Ribosomal_L11_bac-type.
[Graphical view]

Gene3D

G3DSA:1.10.10.250. Ribosomal_L11. 1 hit.

PANTHER

PTHR11661:SF1. Ribosom_L11_bac. 1 hit.
PTHR11661. Ribosomal_L11. 1 hit.

Pfam

PF00298. Ribosomal_L11. 1 hit.
PF03946. Ribosomal_L11_N. 1 hit.
[Graphical view]

ProDom

PD001367. Ribosomal_L11. 1 hit.
[Graphical view] [Entries sharing at least one domain]

SMART

SM00649. RL11. 1 hit.
[Graphical view]

TIGRFAMs

TIGR01632. L11_bact. 1 hit.

PROSITE

PS00359. RIBOSOMAL_L11. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

RL11_THEMA

Accession

Primary (citable) accession number: P29395

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 1992
Last sequence update:	January 23, 2007
Last modified:	November 3, 2009
This is version 78 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)