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P29395

- RL11_THEMA

UniProt

P29395 - RL11_THEMA

Protein

50S ribosomal protein L11

Gene

rplK

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 115 (01 Oct 2014)
      Sequence version 3 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.

    GO - Molecular functioni

    1. large ribosomal subunit rRNA binding Source: UniProtKB-HAMAP
    2. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    50S ribosomal protein L11UniRule annotation
    Gene namesi
    Name:rplKUniRule annotation
    Ordered Locus Names:TM_0454
    OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    Taxonomic identifieri243274 [NCBI]
    Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
    ProteomesiUP000008183: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. ribosome Source: UniProtKB-KW

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedBy similarity
    Chaini2 – 14114050S ribosomal protein L11PRO_0000104397Add
    BLAST

    Post-translational modificationi

    One or more lysine residues are methylated.UniRule annotation

    Keywords - PTMi

    Methylation

    Interactioni

    Subunit structurei

    Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which 3 L12 dimers bind in a sequential fashion forming a heptameric L10(L12)2(L12)2(L12)2 complex.

    Protein-protein interaction databases

    MINTiMINT-208764.
    STRINGi243274.TM0454.

    Structurei

    Secondary structure

    1
    141
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi9 – 146
    Turni21 – 255
    Helixi26 – 294
    Turni30 – 323
    Helixi35 – 4511
    Turni46 – 483
    Beta strandi51 – 6010
    Beta strandi62 – 643
    Beta strandi66 – 705
    Helixi75 – 839
    Turni92 – 943
    Beta strandi98 – 1014
    Helixi102 – 11211
    Helixi113 – 1153
    Helixi121 – 13212
    Turni133 – 1364
    Beta strandi137 – 1404

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1IP8model-G-[»]
    1JQMelectron microscopy-A2-140[»]
    1JQSelectron microscopy-A2-140[»]
    1JQTelectron microscopy-A2-140[»]
    1MMSX-ray2.57A/B2-141[»]
    1MVRelectron microscopy12.80L2-141[»]
    1OLNNMR-A2-141[»]
    1PN7electron microscopy10.80L8-140[»]
    1PN8electron microscopy10.80L8-140[»]
    1R2Welectron microscopy9.00A2-141[»]
    1R2Xelectron microscopy9.00A2-141[»]
    2BCWelectron microscopy11.20A8-72[»]
    2GKYmodel-A8-140[»]
    2GKZmodel-A8-140[»]
    2JQ7NMR-A1-141[»]
    2K3FNMR-A1-141[»]
    ProteinModelPortaliP29395.
    SMRiP29395. Positions 1-141.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP29395.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L11P family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0080.
    KOiK02867.
    OMAiANYLHEQ.
    OrthoDBiEOG69PQ9D.

    Family and domain databases

    Gene3Di1.10.10.250. 1 hit.
    3.30.1550.10. 1 hit.
    HAMAPiMF_00736. Ribosomal_L11.
    InterProiIPR000911. Ribosomal_L11/L12.
    IPR006519. Ribosomal_L11_bac-typ.
    IPR020783. Ribosomal_L11_C.
    IPR020785. Ribosomal_L11_CS.
    IPR020784. Ribosomal_L11_N.
    [Graphical view]
    PANTHERiPTHR11661. PTHR11661. 1 hit.
    PfamiPF00298. Ribosomal_L11. 1 hit.
    PF03946. Ribosomal_L11_N. 1 hit.
    [Graphical view]
    SMARTiSM00649. RL11. 1 hit.
    [Graphical view]
    SUPFAMiSSF46906. SSF46906. 1 hit.
    SSF54747. SSF54747. 1 hit.
    TIGRFAMsiTIGR01632. L11_bact. 1 hit.
    PROSITEiPS00359. RIBOSOMAL_L11. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P29395-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKKVAAQIK LQLPAGKATP APPVGPALGQ HGVNIMEFCK RFNAETADKA    50
    GMILPVVITV YEDKSFTFII KTPPASFLLK KAAGIEKGSS EPKRKIVGKV 100
    TRKQIEEIAK TKMPDLNANS LEAAMKIIEG TAKSMGIEVV D 141
    Length:141
    Mass (Da):15,089
    Last modified:January 23, 2007 - v3
    Checksum:i08AD83D090F651A9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z11839 Genomic DNA. Translation: CAA77859.1.
    AE000512 Genomic DNA. Translation: AAD35537.1.
    PIRiB44466. R5HG11.
    RefSeqiNP_228264.1. NC_000853.1.
    YP_007976801.1. NC_021214.1.
    YP_008990576.1. NC_023151.1.

    Genome annotation databases

    EnsemblBacteriaiAAD35537; AAD35537; TM_0454.
    GeneIDi897484.
    KEGGitma:TM0454.
    tmi:THEMA_02420.
    tmm:Tmari_0451.
    PATRICi23935803. VBITheMar51294_0460.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z11839 Genomic DNA. Translation: CAA77859.1 .
    AE000512 Genomic DNA. Translation: AAD35537.1 .
    PIRi B44466. R5HG11.
    RefSeqi NP_228264.1. NC_000853.1.
    YP_007976801.1. NC_021214.1.
    YP_008990576.1. NC_023151.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1IP8 model - G - [» ]
    1JQM electron microscopy - A 2-140 [» ]
    1JQS electron microscopy - A 2-140 [» ]
    1JQT electron microscopy - A 2-140 [» ]
    1MMS X-ray 2.57 A/B 2-141 [» ]
    1MVR electron microscopy 12.80 L 2-141 [» ]
    1OLN NMR - A 2-141 [» ]
    1PN7 electron microscopy 10.80 L 8-140 [» ]
    1PN8 electron microscopy 10.80 L 8-140 [» ]
    1R2W electron microscopy 9.00 A 2-141 [» ]
    1R2X electron microscopy 9.00 A 2-141 [» ]
    2BCW electron microscopy 11.20 A 8-72 [» ]
    2GKY model - A 8-140 [» ]
    2GKZ model - A 8-140 [» ]
    2JQ7 NMR - A 1-141 [» ]
    2K3F NMR - A 1-141 [» ]
    ProteinModelPortali P29395.
    SMRi P29395. Positions 1-141.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-208764.
    STRINGi 243274.TM0454.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAD35537 ; AAD35537 ; TM_0454 .
    GeneIDi 897484.
    KEGGi tma:TM0454.
    tmi:THEMA_02420.
    tmm:Tmari_0451.
    PATRICi 23935803. VBITheMar51294_0460.

    Phylogenomic databases

    eggNOGi COG0080.
    KOi K02867.
    OMAi ANYLHEQ.
    OrthoDBi EOG69PQ9D.

    Miscellaneous databases

    EvolutionaryTracei P29395.

    Family and domain databases

    Gene3Di 1.10.10.250. 1 hit.
    3.30.1550.10. 1 hit.
    HAMAPi MF_00736. Ribosomal_L11.
    InterProi IPR000911. Ribosomal_L11/L12.
    IPR006519. Ribosomal_L11_bac-typ.
    IPR020783. Ribosomal_L11_C.
    IPR020785. Ribosomal_L11_CS.
    IPR020784. Ribosomal_L11_N.
    [Graphical view ]
    PANTHERi PTHR11661. PTHR11661. 1 hit.
    Pfami PF00298. Ribosomal_L11. 1 hit.
    PF03946. Ribosomal_L11_N. 1 hit.
    [Graphical view ]
    SMARTi SM00649. RL11. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46906. SSF46906. 1 hit.
    SSF54747. SSF54747. 1 hit.
    TIGRFAMsi TIGR01632. L11_bact. 1 hit.
    PROSITEi PS00359. RIBOSOMAL_L11. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The organization and expression of essential transcription translation component genes in the extremely thermophilic eubacterium Thermotoga maritima."
      Liao D., Dennis P.P.
      J. Biol. Chem. 267:22787-22797(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
    3. "A detailed view of a ribosomal active site: the structure of the L11-RNA complex."
      Wimberly B.T., Guymon R., McCutcheon J.P., White S.W., Ramakrishnan V.
      Cell 97:491-502(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.57 ANGSTROMS).

    Entry informationi

    Entry nameiRL11_THEMA
    AccessioniPrimary (citable) accession number: P29395
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 1992
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 115 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3