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Protein

50S ribosomal protein L11

Gene

rplK

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L11UniRule annotation
Gene namesi
Name:rplKUniRule annotation
Ordered Locus Names:TM_0454
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
Proteomesi
  • UP000008183 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Chemistry databases

DrugBankiDB02566. 8-Hydroxy-4-(1-Hydroxyethyl)Quinoline-2-Carboxylic Acid.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001043972 – 14150S ribosomal protein L11Add BLAST140

Post-translational modificationi

One or more lysine residues are methylated.UniRule annotation

Keywords - PTMi

Methylation

Interactioni

Subunit structurei

Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which 3 L12 dimers bind in a sequential fashion forming a heptameric L10(L12)2(L12)2(L12)2 complex.

Protein-protein interaction databases

MINTiMINT-208764.
STRINGi243274.TM0454.

Structurei

Secondary structure

1141
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi9 – 14Combined sources6
Turni21 – 25Combined sources5
Helixi26 – 29Combined sources4
Turni30 – 32Combined sources3
Helixi35 – 45Combined sources11
Turni46 – 48Combined sources3
Beta strandi51 – 60Combined sources10
Beta strandi62 – 64Combined sources3
Beta strandi66 – 70Combined sources5
Helixi75 – 83Combined sources9
Turni92 – 94Combined sources3
Beta strandi98 – 101Combined sources4
Helixi102 – 112Combined sources11
Helixi113 – 115Combined sources3
Helixi121 – 132Combined sources12
Turni133 – 136Combined sources4
Beta strandi137 – 140Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1IP8model-G-[»]
1JQMelectron microscopy-A2-140[»]
1JQSelectron microscopy-A2-140[»]
1JQTelectron microscopy-A2-140[»]
1MMSX-ray2.57A/B2-141[»]
1MVRelectron microscopy12.80L2-141[»]
1OLNNMR-A2-141[»]
1PN7electron microscopy10.80L8-140[»]
1PN8electron microscopy10.80L8-140[»]
1R2Welectron microscopy9.00A2-141[»]
1R2Xelectron microscopy9.00A2-141[»]
2BCWelectron microscopy11.20A8-72[»]
2GKYmodel-A8-140[»]
2GKZmodel-A8-140[»]
2JQ7NMR-A1-141[»]
2K3FNMR-A1-141[»]
ProteinModelPortaliP29395.
SMRiP29395.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP29395.

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uL11 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UIK. Bacteria.
COG0080. LUCA.
InParanoidiP29395.
KOiK02867.
OMAiCKQFNAK.

Family and domain databases

CDDicd00349. Ribosomal_L11. 1 hit.
Gene3Di1.10.10.250. 1 hit.
3.30.1550.10. 1 hit.
HAMAPiMF_00736. Ribosomal_L11. 1 hit.
InterProiView protein in InterPro
IPR000911. Ribosomal_L11/L12.
IPR006519. Ribosomal_L11_bac-typ.
IPR020783. Ribosomal_L11_C.
IPR020785. Ribosomal_L11_CS.
IPR020784. Ribosomal_L11_N.
PANTHERiPTHR11661. PTHR11661. 1 hit.
PfamiView protein in Pfam
PF00298. Ribosomal_L11. 1 hit.
PF03946. Ribosomal_L11_N. 1 hit.
SMARTiView protein in SMART
SM00649. RL11. 1 hit.
SUPFAMiSSF46906. SSF46906. 1 hit.
SSF54747. SSF54747. 1 hit.
TIGRFAMsiTIGR01632. L11_bact. 1 hit.
PROSITEiView protein in PROSITE
PS00359. RIBOSOMAL_L11. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P29395-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKKVAAQIK LQLPAGKATP APPVGPALGQ HGVNIMEFCK RFNAETADKA
60 70 80 90 100
GMILPVVITV YEDKSFTFII KTPPASFLLK KAAGIEKGSS EPKRKIVGKV
110 120 130 140
TRKQIEEIAK TKMPDLNANS LEAAMKIIEG TAKSMGIEVV D
Length:141
Mass (Da):15,089
Last modified:January 23, 2007 - v3
Checksum:i08AD83D090F651A9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z11839 Genomic DNA. Translation: CAA77859.1.
AE000512 Genomic DNA. Translation: AAD35537.1.
PIRiB44466. R5HG11.
RefSeqiNP_228264.1. NC_000853.1.
WP_004081512.1. NZ_CP011107.1.

Genome annotation databases

EnsemblBacteriaiAAD35537; AAD35537; TM_0454.
GeneIDi897484.
KEGGitma:TM0454.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiRL11_THEMA
AccessioniPrimary (citable) accession number: P29395
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: January 23, 2007
Last modified: June 7, 2017
This is version 138 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families