Agamous-like MADS-box protein AGL6 - Arabidopsis thaliana (Mouse-ear cress)

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P29386 (AGL6_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 101. History...

Clusters with 100%, 90%, 50% identity |

Documents (2) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Agamous-like MADS-box protein AGL6

Gene names

Name:	AGL6
Ordered Locus Names:	At2g45650
ORF Names:	F17K2.18

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	252 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Probable transcription factor. Forms a heterodimer via the K-box domain with AG, that could be involved in genes regulation during floral meristem development.
Subunit structure	Forms a heterodimer with AGAMOUS. Interacts with AGL15 and AGL16. Ref.5
Subcellular location	Nucleus.
Tissue specificity	Preferentially expressed in flowers.
Sequence similarities	Contains 1 K-box domain. Contains 1 MADS-box domain.

Ontologies

Keywords
Biological process	Differentiation Flowering Transcription Transcription regulation
Cellular component	Nucleus
Domain	Coiled coil
Ligand	DNA-binding
Molecular function	Developmental protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell differentiation Inferred from electronic annotation. Source: UniProtKB-KW floral organ development Inferred from mutant phenotype PubMed 20230491. Source: TAIR positive regulation of flower development Inferred from mutant phenotype PubMed 21175890. Source: TAIR transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW vegetative to reproductive phase transition of meristem Inferred from mutant phenotype PubMed 20230491. Source: TAIR
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW sequence-specific DNA binding transcription factor activity Inferred from sequence or structural similarity PubMed 11118137 PubMed 12837945 Ref.1. Source: TAIR
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 252

252

Agamous-like MADS-box protein AGL6

PRO_0000199460

Regions

Domain

3 – 57

MADS-box

Domain

86 – 176

K-box

Coiled coil

91 – 173

Potential

Sequences

Sequence

Length

Mass (Da)

Tools

P29386 [UniParc].

Last modified February 1, 1996. Version 2.
Checksum: F763A4A71515CF20
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FASTA

252

28,745

        10         20         30         40         50         60 
MGRGRVEMKR IENKINRQVT FSKRRNGLLK KAYELSVLCD AEVALIIFSS RGKLYEFGSV 

        70         80         90        100        110        120 
GIESTIERYN RCYNCSLSNN KPEETTQSWC QEVTKLKSKY ESLVRTNRNL LGEDLGEMGV 

       130        140        150        160        170        180 
KELQALERQL EAALTATRQR KTQVMMEEME DLRKKERQLG DINKQLKIKF ETEGHAFKTF 

       190        200        210        220        230        240 
QDLWANSAAS VAGDPNNSEF PVEPSHPNVL DCNTEPFLQI GFQQHYYVQG EGSSVSKSNV 

       250 
AGETNFVQGW VL

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"AGL1-AGL6, an Arabidopsis gene family with similarity to floral homeotic and transcription factor genes." Ma H., Yanofsky M.F., Meyerowitz E.M. Genes Dev. 5:484-495(1991) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Landsberg erecta.
[2]	"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana." Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. Venter J.C. Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[3]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[4]	"Specific interactions between the K domains of AG and AGLs, members of the MADS domain family of DNA binding proteins." Fan H.-Y., Hu Y., Tudor M., Ma H. Plant J. 12:999-1010(1997) [PubMed] [Europe PMC] [Abstract] Cited for: CHARACTERIZATION.
[5]	"Comprehensive interaction map of the Arabidopsis MADS Box transcription factors." de Folter S., Immink R.G.H., Kieffer M., Parenicova L., Henz S.R., Weigel D., Busscher M., Kooiker M., Colombo L., Kater M.M., Davies B., Angenent G.C. Plant Cell 17:1424-1433(2005) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH AGL15 AND AGL16.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M55554 mRNA. Translation: AAA79328.1. AC003680 Genomic DNA. Translation: AAC06173.1. CP002685 Genomic DNA. Translation: AEC10582.1.
IPI	IPI00531522.
PIR	F39534.
RefSeq	NP_182089.1. NM_130127.1.
UniGene	At.512.
3D structure databases
ProteinModelPortal	P29386.
SMR	P29386. Positions 2-69.
ModBase	Search...
Protein-protein interaction databases
IntAct	P29386. 20 interactions.
STRING	3702.AT2G45650.1-P.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT2G45650.1; AT2G45650.1; AT2G45650.
GeneID	819173.
KEGG	ath:AT2G45650.
Organism-specific databases
GeneFarm	3546. 359.
TAIR	At2g45650.
Phylogenomic databases
eggNOG	COG5068.
InParanoid	P29386.
KO	K09264.
OMA	KERQLGD.
PhylomeDB	P29386.
ProtClustDB	CLSN2913049.
Gene expression databases
ArrayExpress	P29386.
Genevestigator	P29386.
Family and domain databases
InterPro	IPR002487. TF_Kbox. IPR002100. TF_MADSbox. [Graphical view]
Pfam	PF01486. K-box. 1 hit. PF00319. SRF-TF. 1 hit. [Graphical view]
PRINTS	PR00404. MADSDOMAIN.
SMART	SM00432. MADS. 1 hit. [Graphical view]
SUPFAM	SSF55455. TF_MADSbox. 1 hit.
PROSITE	PS51297. K_BOX. 1 hit. PS00350. MADS_BOX_1. 1 hit. PS50066. MADS_BOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AGL6_ARATH

Accession

Primary (citable) accession number: P29386

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 1992
Last sequence update:	February 1, 1996
Last modified:	May 1, 2013
This is version 101 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Entry information

Relevant documents