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Protein

Agamous-like MADS-box protein AGL3

Gene

AGL3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probable transcription factor that binds specifically to the CArG box DNA sequence 5'-CC (A/T)6 GG-3' (PubMed:7632923, PubMed:25183521). Plays an important role in the determination of flower meristem identity. Involved in the specification of sepal identity. Contributes to the development of petals, stamens and carpels (PubMed:15530395).3 Publications

GO - Molecular functioni

GO - Biological processi

  • carpel development Source: TAIR
  • cell differentiation Source: UniProtKB-KW
  • maintenance of floral meristem identity Source: TAIR
  • petal development Source: TAIR
  • positive regulation of transcription by RNA polymerase II Source: InterPro
  • sepal development Source: TAIR
  • stamen development Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionDevelopmental protein, DNA-binding
Biological processDifferentiation, Flowering, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Agamous-like MADS-box protein AGL3
Alternative name(s):
Protein SEPALLATA 41 Publication
Gene namesi
Name:AGL3
Synonyms:SEP41 Publication
Ordered Locus Names:At2g03710
ORF Names:F19B11.16
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G03710
TAIRilocus:2044259 AT2G03710

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001994581 – 258Agamous-like MADS-box protein AGL3Add BLAST258

Proteomic databases

PaxDbiP29383

Expressioni

Tissue specificityi

Expressed in aerial vegetative organs and flowers, but not in roots (PubMed:7632923). Expressed in flower primordia (PubMed:15530395).2 Publications

Gene expression databases

ExpressionAtlasiP29383 baseline and differential
GenevisibleiP29383 AT

Interactioni

Subunit structurei

Forms homodimers (PubMed:25183521). Interacts with TT16/AGL32 (PubMed:16080001).2 Publications

GO - Molecular functioni

Protein-protein interaction databases

BioGridi299, 10 interactors
DIPiDIP-33748N
IntActiP29383, 18 interactors
STRINGi3702.AT2G03710.1

Structurei

3D structure databases

ProteinModelPortaliP29383
SMRiP29383
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 57MADS-boxPROSITE-ProRule annotationAdd BLAST55
Domaini88 – 178K-boxPROSITE-ProRule annotationAdd BLAST91

Phylogenomic databases

eggNOGiKOG0014 Eukaryota
COG5068 LUCA
HOGENOMiHOG000155301
InParanoidiP29383
OMAiQNVNGFF
OrthoDBiEOG09360JNU
PhylomeDBiP29383

Family and domain databases

CDDicd00265 MADS_MEF2_like, 1 hit
Gene3Di3.40.1810.10, 1 hit
InterProiView protein in InterPro
IPR033896 MADS_MEF2-like
IPR002487 TF_Kbox
IPR002100 TF_MADSbox
IPR036879 TF_MADSbox_sf
PfamiView protein in Pfam
PF01486 K-box, 1 hit
PF00319 SRF-TF, 1 hit
PRINTSiPR00404 MADSDOMAIN
SMARTiView protein in SMART
SM00432 MADS, 1 hit
SUPFAMiSSF55455 SSF55455, 1 hit
PROSITEiView protein in PROSITE
PS51297 K_BOX, 1 hit
PS00350 MADS_BOX_1, 1 hit
PS50066 MADS_BOX_2, 1 hit

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: P29383-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MGRGKVELKR IENKINRQVT FAKRRNGLLK KAYELSVLCD AEIALLIFSN
60 70 80 90 100
RGKLYEFCSS PSGMARTVDK YRKHSYATMD PNQSAKDLQD KYQDYLKLKS
110 120 130 140 150
RVEILQHSQR HLLGEELSEM DVNELEHLER QVDASLRQIR STKARSMLDQ
160 170 180 190 200
LSDLKTKEEM LLETNRDLRR KLEDSDAALT QSFWGSSAAE QQQQHQQQQQ
210 220 230 240 250
GMSSYQSNPP IQEAGFFKPL QGNVALQMSS HYNHNPANAT NSATTSQNVN

GFFPGWMV
Length:258
Mass (Da):29,573
Last modified:December 15, 1998 - v2
Checksum:iA642CA7EA58AB38D
GO
Isoform 2 (identifier: P29383-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     172-258: LEDSDAALTQ...VNGFFPGWMV → VAIGIFYRKKLKPFVI

Note: No experimental confirmation available.
Show »
Length:187
Mass (Da):21,934
Checksum:iF02166DACB15265B
GO
Isoform 3 (identifier: P29383-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     229-229: Missing.

Show »
Length:257
Mass (Da):29,486
Checksum:i09D3131DD87437E1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti58 – 92Missing (PubMed:1672119).CuratedAdd BLAST35

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_008908172 – 258LEDSD…PGWMV → VAIGIFYRKKLKPFVI in isoform 2. 1 PublicationAdd BLAST87
Alternative sequenceiVSP_041587229Missing in isoform 3. 1 Publication1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U81369 mRNA Translation: AAB38975.1
AY141229 mRNA Translation: AAN52793.1
AC006836 Genomic DNA Translation: AAD20073.1
CP002685 Genomic DNA Translation: AEC05738.1
CP002685 Genomic DNA Translation: AEC05739.1
CP002685 Genomic DNA Translation: AEC05740.1
AY063894 mRNA Translation: AAL36250.1
AY096386 mRNA Translation: AAM20027.1
PIRiS57793
RefSeqiNP_178466.1, NM_126418.2 [P29383-1]
NP_849930.1, NM_179599.2 [P29383-3]
NP_973411.1, NM_201682.3 [P29383-2]
UniGeneiAt.10200

Genome annotation databases

EnsemblPlantsiAT2G03710.1; AT2G03710.1; AT2G03710 [P29383-1]
AT2G03710.2; AT2G03710.2; AT2G03710 [P29383-3]
AT2G03710.3; AT2G03710.3; AT2G03710 [P29383-2]
GeneIDi814898
GrameneiAT2G03710.1; AT2G03710.1; AT2G03710 [P29383-1]
AT2G03710.2; AT2G03710.2; AT2G03710 [P29383-3]
AT2G03710.3; AT2G03710.3; AT2G03710 [P29383-2]
KEGGiath:AT2G03710

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiAGL3_ARATH
AccessioniPrimary (citable) accession number: P29383
Secondary accession number(s): O04729
, Q41252, Q7XJL0, Q8VZR9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 15, 1998
Last modified: April 25, 2018
This is version 154 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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