Reviewed, UniProtKB/Swiss-Prot P29380 (CYC1_ARATH)

Names and origin

Protein names

Recommended name:
    Cytochrome c

Gene names

Name:

CC-1

Organism

Arabidopsis thaliana (Mouse-ear cress)

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

Protein attributes

Sequence length	112 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
Subcellular location	Mitochondrion matrix.
Post-translational modification	Binds 1 heme group per subunit.
Sequence similarities	Belongs to the cytochrome c family.
Caution	This protein probably does not originate from A.thaliana, rather it resemble fungal cytochrome c.

Ontologies

Keywords
Biological process	Electron transport Respiratory chain Transport
Cellular component	Mitochondrion
Ligand	Heme Iron Metal-binding
Gene Ontology (GO)
Biological process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	mitochondrial matrix Inferred from electronic annotation. Source: UniProtKB-SubCell respiratory chain Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 112	112	Cytochrome c		PRO_0000108284
Sites
	Metal binding	27	1	Iron (heme axial ligand) By similarity
	Metal binding	89	1	Iron (heme axial ligand) By similarity
	Binding site	23	1	Heme (covalent) By similarity
	Binding site	26	1	Heme (covalent) By similarity

Sequences

	Sequence		Length	Mass (Da)
	P29380-1 [UniParc]. Last modified December 1, 1992. Version 1. Checksum: 6373346FE583C938	FASTA	112	12,441
	10 20 30 40 50 60 MQVADISLQG DAKKGANLFK TRCAQCHTLK AGEGNKIGPE LHGLFGRKTG SVAGYSYTDA 70 80 90 100 110 NKQKGIEWKD DTLFEYLENP KKYIPGTKMA FGGLKKPKDR NDLITFLEEE TK

References

[1]	"Structure and molecular evolutionary analysis of a plant cytochrome c gene: surprising implications for Arabidopsis thaliana." Kemmerer E.C., Lei M., Wu R. J. Mol. Evol. 32:227-237(1991) [PubMed: 1646338] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: cv. Columbia.

Web resources

Protein Spotlight

Life shuttle - Issue 76 of November 2006

Cross-references

Sequence databases
EMBLGenBankDDBJ	X59459 Genomic DNA. Translation: CAA42069.1. M85253 Genomic DNA. Translation: AAA32747.1.
IPI	IPI00533381.
3D structure databases
SMR	P29380. Positions 10-109.
ModBase	Search...
Gene expression databases
ArrayExpress	P29380.
Genevestigator	P29380.
Family and domain databases
InterPro	IPR002327. Cyt_c_1A/1B. IPR003088. Cyt_c_I. IPR009056. Cyt_c_monohaem. [Graphical view]
Gene3D	G3DSA:1.10.760.10. Cytochrome_c_R. 1 hit.
PANTHER	PTHR11961. Cyt_CIAB. 1 hit.
Pfam	PF00034. Cytochrom_C. 1 hit. [Graphical view]
PRINTS	PR00604. CYTCHRMECIAB.
PROSITE	PS51007. CYTC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CYC1_ARATH

Accession

Primary (citable) accession number: P29380

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 1992
Last sequence update:	December 1, 1992
Last modified:	November 24, 2009
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)