##gff-version 3
P29371	UniProtKB	Chain	1	465	.	.	.	ID=PRO_0000069899;Note=Neuromedin-K receptor	
P29371	UniProtKB	Topological domain	1	84	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P29371	UniProtKB	Transmembrane	85	107	.	.	.	Note=Helical%3B Name%3D1;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P29371	UniProtKB	Topological domain	108	117	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P29371	UniProtKB	Transmembrane	118	139	.	.	.	Note=Helical%3B Name%3D2;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P29371	UniProtKB	Topological domain	140	159	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P29371	UniProtKB	Transmembrane	160	181	.	.	.	Note=Helical%3B Name%3D3;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P29371	UniProtKB	Topological domain	182	201	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P29371	UniProtKB	Transmembrane	202	222	.	.	.	Note=Helical%3B Name%3D4;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P29371	UniProtKB	Topological domain	223	245	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P29371	UniProtKB	Transmembrane	246	270	.	.	.	Note=Helical%3B Name%3D5;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P29371	UniProtKB	Topological domain	271	299	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P29371	UniProtKB	Transmembrane	300	321	.	.	.	Note=Helical%3B Name%3D6;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P29371	UniProtKB	Topological domain	322	334	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P29371	UniProtKB	Transmembrane	335	359	.	.	.	Note=Helical%3B Name%3D7;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P29371	UniProtKB	Topological domain	360	465	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P29371	UniProtKB	Region	415	465	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P29371	UniProtKB	Compositional bias	436	465	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P29371	UniProtKB	Lipidation	374	374	.	.	.	Note=S-palmitoyl cysteine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P29371	UniProtKB	Glycosylation	23	23	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P29371	UniProtKB	Glycosylation	50	50	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P29371	UniProtKB	Glycosylation	73	73	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P29371	UniProtKB	Disulfide bond	158	233	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00521	
P29371	UniProtKB	Natural variant	93	93	.	.	.	ID=VAR_069177;Note=In HH11%3B unequivocal evidence of impaired receptor signaling. G->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19079066;Dbxref=dbSNP:rs121918124,PMID:19079066	
P29371	UniProtKB	Natural variant	137	137	.	.	.	ID=VAR_072976;Note=In HH11. F->V;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:25077900;Dbxref=PMID:25077900	
P29371	UniProtKB	Natural variant	286	286	.	.	.	ID=VAR_049422;Note=May contribute to hypogonadotropic hypogonadism in patients carrying disease-causing mutations in FGFR1. K->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23643382;Dbxref=dbSNP:rs2276973,PMID:23643382	
P29371	UniProtKB	Natural variant	346	346	.	.	.	ID=VAR_072977;Note=In HH11. M->V;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:25077900;Dbxref=dbSNP:rs200148989,PMID:25077900	
P29371	UniProtKB	Natural variant	353	353	.	.	.	ID=VAR_069178;Note=In HH11%3B unequivocal evidence of impaired receptor signaling. P->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19079066;Dbxref=dbSNP:rs121918125,PMID:19079066	
P29371	UniProtKB	Natural variant	364	364	.	.	.	ID=VAR_069963;Note=In HH11%3B the patient also carries a mutation in FGFR1. R->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23643382;Dbxref=dbSNP:rs150288991,PMID:23643382	
P29371	UniProtKB	Natural variant	449	449	.	.	.	ID=VAR_049423;Note=May contribute to hypogonadotropic hypogonadism in patients carrying disease-causing mutations in SPRY4 or KAL1. A->T;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23643382;Dbxref=dbSNP:rs17033889,PMID:23643382	
P29371	UniProtKB	Sequence conflict	3	3	.	.	.	Note=T->I;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P29371	UniProtKB	Sequence conflict	63	63	.	.	.	Note=A->R;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P29371	UniProtKB	Sequence conflict	439	439	.	.	.	Note=C->F;Ontology_term=ECO:0000305;evidence=ECO:0000305