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P29284

- FLP_LACCA

UniProt

P29284 - FLP_LACCA

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Protein

Probable transcriptional regulator flp

Gene

flp

Organism
Lactobacillus casei
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi191 – 21020H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable transcriptional regulator flp
Gene namesi
Name:flp
OrganismiLactobacillus casei
Taxonomic identifieri1582 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Subcellular locationi

GO - Cellular componenti

  1. intracellular Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 219219Probable transcriptional regulator flpPRO_0000100160Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP29284.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini144 – 21269HTH crp-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 cyclic nucleotide-binding domain.PROSITE-ProRule annotation
Contains 1 HTH crp-type DNA-binding domain.PROSITE-ProRule annotation

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProiIPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR012318. HTH_CRP_2.
IPR014710. RmlC-like_jellyroll.
IPR001808. Tscrpt_reg_HTH_Crp.
IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00027. cNMP_binding. 1 hit.
PF00325. Crp. 1 hit.
[Graphical view]
PRINTSiPR00034. HTHCRP.
SMARTiSM00100. cNMP. 1 hit.
SM00419. HTH_CRP. 1 hit.
[Graphical view]
SUPFAMiSSF51206. SSF51206. 1 hit.
PROSITEiPS50042. CNMP_BINDING_3. 1 hit.
PS00042. HTH_CRP_1. 1 hit.
PS51063. HTH_CRP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P29284-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAHSCTAVVP LFKNLNDEAR AAIDALTHER QVEKGTVLIS PDTAAHLLVV
60 70 80 90 100
AHGKLKTYQL ATNGKEQLLR VDGVGDYEGE AGLLNIANPN VYTETLTAAT
110 120 130 140 150
VCTISATDFQ QLLLKQPQIS LQLLTENARK MQALEKQAGY LGNDSINVRL
160 170 180 190 200
THYLLDLRTA AGQDTVTVPM AWTQLADYLG TTPETVSRTL KRLAEEKLIE
210
RSGKQVRILN AEDMEDFAW
Length:219
Mass (Da):24,102
Last modified:December 1, 1992 - v1
Checksum:i6898945F6D914E2B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D00496 Genomic DNA. Translation: BAA00388.1.
PIRiS42348. JS0345.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D00496 Genomic DNA. Translation: BAA00388.1 .
PIRi S42348. JS0345.

3D structure databases

ProteinModelPortali P29284.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProi IPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR012318. HTH_CRP_2.
IPR014710. RmlC-like_jellyroll.
IPR001808. Tscrpt_reg_HTH_Crp.
IPR018335. Tscrpt_reg_HTH_Crp-type_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00027. cNMP_binding. 1 hit.
PF00325. Crp. 1 hit.
[Graphical view ]
PRINTSi PR00034. HTHCRP.
SMARTi SM00100. cNMP. 1 hit.
SM00419. HTH_CRP. 1 hit.
[Graphical view ]
SUPFAMi SSF51206. SSF51206. 1 hit.
PROSITEi PS50042. CNMP_BINDING_3. 1 hit.
PS00042. HTH_CRP_1. 1 hit.
PS51063. HTH_CRP_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Nucleotide sequences and genomic constitution of five tryptophan genes of Lactobacillus casei."
    Natori Y., Kano Y., Imamoto F.
    J. Biochem. 107:248-255(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: RNL7.
  2. "Lactobacillus casei contains a member of the CRP-FNR family."
    Irvine A.S., Guest J.R.
    Nucleic Acids Res. 21:753-753(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: SIMILARITY TO CRP/FNR FAMILY.

Entry informationi

Entry nameiFLP_LACCA
AccessioniPrimary (citable) accession number: P29284
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 1, 1992
Last modified: October 1, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3