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P29238 (LUXA2_PHOLE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 27, 2011. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alkanal monooxygenase alpha chain

EC=1.14.14.3
Alternative name(s):
Bacterial luciferase alpha chain
Gene names
Name:luxA
OrganismPhotobacterium leiognathi
Taxonomic identifier553611 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaePhotobacterium

Protein attributes

Sequence length354 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Light-emitting reaction in luminous bacteria.

Catalytic activity

RCHO + reduced FMN + O2 = RCOOH + FMN + H2O + light.

Subunit structure

Heterodimer of an alpha and a beta chain.

Sequence similarities

Belongs to the bacterial luciferase oxidoreductase family.

Ontologies

Keywords
   Biological processLuminescence
   LigandFMN
Flavoprotein
   Molecular functionMonooxygenase
Oxidoreductase
Photoprotein
Gene Ontology (GO)
   Biological processbioluminescence

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionalkanal monooxygenase (FMN-linked) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 354354Alkanal monooxygenase alpha chain
PRO_0000220165

Sequences

Sequence LengthMass (Da)Tools
P29238 [UniParc].

Last modified December 1, 1992. Version 1.
Checksum: 07001C2064F4645B

FASTA35440,402
        10         20         30         40         50         60 
MKISNICFSY QPPGESHQEV MERFIRLGVA SEELNFDGFY TLEHHFTEFG ITGNLYIACA 

        70         80         90        100        110        120 
NILGRTKRIQ VGTMGIVLPT EHPARHVESL LVLDQLSKGR FNYGTVRGLY HKDFRVFGTS 

       130        140        150        160        170        180 
QEDSRKTAEN FYSMILDASK TGVLHTDGEV VEFPDVNVYP EAYSKKQPTC MTAESSETIT 

       190        200        210        220        230        240 
YLAERGLPMV LSWIIPVSEK VSQMELYNEV AAEHGHDINN IEHILTFICS VNEDGEKADS 

       250        260        270        280        290        300 
VCRNFLENWY DSYKNATNIF NDSNQTRGYD YLKAQWREWV MKGLADPRRR LDYSNELNPV 

       310        320        330        340        350 
GTPERCIEII QSNIDATGIK HITVGFEANG SEQEIRESME LFMEKVAPHL KDPQ 

« Hide

References

[1]"The lux genes of the luminous bacterial symbiont, Photobacterium leiognathi, of the ponyfish. Nucleotide sequence, difference in gene organization, and high expression in mutant Escherichia coli."
Lee C.Y., Szittner R.B., Meighen E.A.
Eur. J. Biochem. 201:161-167(1991) [PubMed: 1915359] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 25521 / L1 / CIP 665.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M63594 Genomic DNA. Translation: AAA25618.1.
PIRS17953.

3D structure databases

ProteinModelPortalP29238.
SMRP29238. Positions 1-354.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR018235. Bacterial_luciferase_CS.
IPR011251. Luciferase-like_dom.
IPR002103. Luciferase_bac.
[Graphical view]
Gene3DG3DSA:3.20.20.30. Luciferase_like. 2 hits.
PfamPF00296. Bac_luciferase. 1 hit.
[Graphical view]
PRINTSPR00089. LUCIFERASE.
SUPFAMSSF51679. Luciferase_like. 1 hit.
PROSITEPS00494. BACTERIAL_LUCIFERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLUXA2_PHOLE
AccessionPrimary (citable) accession number: P29238
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 1, 1992
Last modified: July 27, 2011
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families