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Protein

Phosphoenolpyruvate carboxylase 2

Gene
N/A
Organism
Sorghum bicolor (Sorghum) (Sorghum vulgare)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.

Cofactori

Mg2+By similarity

Pathwayi: C3 acid pathway

This protein is involved in the pathway C3 acid pathway, which is part of Photosynthesis.
View all proteins of this organism that are known to be involved in the pathway C3 acid pathway and in Photosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei167By similarity1
Active sitei595By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAllosteric enzyme, Lyase
Biological processCarbon dioxide fixation, Photosynthesis
LigandMagnesium

Enzyme and pathway databases

UniPathwayiUPA00321

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylase 2 (EC:4.1.1.31)
Short name:
PEPC 2
Short name:
PEPCase 2
Alternative name(s):
CP28
OrganismiSorghum bicolor (Sorghum) (Sorghum vulgare)
Taxonomic identifieri4558 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeSorghinaeSorghum

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001666771 – 960Phosphoenolpyruvate carboxylase 2Add BLAST960

Proteomic databases

PRIDEiP29194

Expressioni

Gene expression databases

ExpressionAtlasiP29194 baseline and differential

Interactioni

Subunit structurei

Homotetramer.

Structurei

3D structure databases

ProteinModelPortaliP29194
SMRiP29194
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.Curated

Phylogenomic databases

eggNOGiENOG410IEAR Eukaryota
COG2352 LUCA

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

P29194-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERLSSIDAQ LRMLVPGKVS EDDKLIEYDA LLLDRFLDIL QDLHGDDLKE
60 70 80 90 100
MVQECYEVAA EYETKHDLQK LDELGKMITS LDPGDSIVIA KSFSHMLNLA
110 120 130 140 150
NLAEEVQIAY RRRIKLKKGD FADENSAITE SDIEETLKRL VVDLKKSPAE
160 170 180 190 200
VFDALKSQTV DLVLTAHPTQ SVRRSLLQKH SRIRNCLVQL YSKDITPDDK
210 220 230 240 250
QELDEALQRE IQAAFRTDEI RRTQPTPQDE MRAGMSYFHE TIWKGVPKFL
260 270 280 290 300
RRVDTALKNI GINERVPYNA PLIQFSSWMG GDRDGNPRVT PEVTRDVCLL
310 320 330 340 350
ARMMASNLYC SQIEDLMFEL SMWRCSDELR MRADELHRST KKDAKHYIEF
360 370 380 390 400
WKKVPPNEPY RVILSDVRDK LYNTRERSRE LLSSGHSDIP EEATLTTVEQ
410 420 430 440 450
LLEPLELCYR SLCACGDRVI ADGSLLDFLR QVSTFGLSLV RLDIRQESDR
460 470 480 490 500
HTDVLDAITT YLGIGSYREW PEERRQEWLL SELNGKRPLF GPDLPKTEEI
510 520 530 540 550
ADVLDTFHVI AELPADNFGA YIISMATAPS DVLAVELLQR ECHVKTPLRV
560 570 580 590 600
VPLFEKLADL EAAPAALARL FSIDWYRQRI NGKQEVMIGY SDSGKDAGRL
610 620 630 640 650
SAAWQLYKAQ EELIKVAKDF GVKLTMFHGR GGTVGRGGGP THLAILSQPP
660 670 680 690 700
DTIHGSLRVT VQGEVIEQSF GEEHLSFRTL QRFTAATLEH GMHPPNAPKP
710 720 730 740 750
EWRTLLDEMA VVATEEYRSI VFQEPRFVEY FRLATPETEY GRMNIGSRPS
760 770 780 790 800
KRKPSGGIES LRAIPWIFAW TQTRFHLPVW LGFGGAFKHV LQKDIRNLHM
810 820 830 840 850
LQEMYNEWPF FRVTIDLVEM VFAKGNPGIA ALYDKLLVSE ELRPLGEKLR
860 870 880 890 900
ANYEETQKLL LQVAGHRDLL EGDPYLKQRL RLRDAYITTL NVCQAYTLKR
910 920 930 940 950
IRDPDYHVAL RPHLSKEIMD PTKAASELVK LNPGSEYAPG LEDTLILTMK
960
GIAAGLQNTG
Length:960
Mass (Da):109,547
Last modified:December 1, 1992 - v1
Checksum:i65FDCE9B71156B18
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59925 Genomic DNA Translation: CAA42549.1
PIRiS18240

Similar proteinsi

Entry informationi

Entry nameiCAPP2_SORBI
AccessioniPrimary (citable) accession number: P29194
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 1, 1992
Last modified: May 23, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health