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P29194 (CAPP2_SORBI) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase 2

Short name=PEPC 2
Short name=PEPCase 2
EC=4.1.1.31
Alternative name(s):
CP28
OrganismSorghum bicolor (Sorghum) (Sorghum vulgare)
Taxonomic identifier4558 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogoneaeSorghum

Protein attributes

Sequence length960 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595

Pathway

Photosynthesis; C3 acid pathway. HAMAP-Rule MF_00595

Subunit structure

Homotetramer.

Subcellular location

Cytoplasm HAMAP-Rule MF_00595.

Sequence similarities

Belongs to the PEPCase type 1 family.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
Photosynthesis
   Cellular componentCytoplasm
   LigandMagnesium
   Molecular functionLyase
   Technical termAllosteric enzyme
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-KW

photosynthesis

Inferred from electronic annotation. Source: UniProtKB-KW

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionphosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 960960Phosphoenolpyruvate carboxylase 2 HAMAP-Rule MF_00595
PRO_0000166677

Sites

Active site1671 By similarity
Active site5951 By similarity

Sequences

Sequence LengthMass (Da)Tools
P29194 [UniParc].

Last modified December 1, 1992. Version 1.
Checksum: 65FDCE9B71156B18

FASTA960109,547
        10         20         30         40         50         60 
MERLSSIDAQ LRMLVPGKVS EDDKLIEYDA LLLDRFLDIL QDLHGDDLKE MVQECYEVAA 

        70         80         90        100        110        120 
EYETKHDLQK LDELGKMITS LDPGDSIVIA KSFSHMLNLA NLAEEVQIAY RRRIKLKKGD 

       130        140        150        160        170        180 
FADENSAITE SDIEETLKRL VVDLKKSPAE VFDALKSQTV DLVLTAHPTQ SVRRSLLQKH 

       190        200        210        220        230        240 
SRIRNCLVQL YSKDITPDDK QELDEALQRE IQAAFRTDEI RRTQPTPQDE MRAGMSYFHE 

       250        260        270        280        290        300 
TIWKGVPKFL RRVDTALKNI GINERVPYNA PLIQFSSWMG GDRDGNPRVT PEVTRDVCLL 

       310        320        330        340        350        360 
ARMMASNLYC SQIEDLMFEL SMWRCSDELR MRADELHRST KKDAKHYIEF WKKVPPNEPY 

       370        380        390        400        410        420 
RVILSDVRDK LYNTRERSRE LLSSGHSDIP EEATLTTVEQ LLEPLELCYR SLCACGDRVI 

       430        440        450        460        470        480 
ADGSLLDFLR QVSTFGLSLV RLDIRQESDR HTDVLDAITT YLGIGSYREW PEERRQEWLL 

       490        500        510        520        530        540 
SELNGKRPLF GPDLPKTEEI ADVLDTFHVI AELPADNFGA YIISMATAPS DVLAVELLQR 

       550        560        570        580        590        600 
ECHVKTPLRV VPLFEKLADL EAAPAALARL FSIDWYRQRI NGKQEVMIGY SDSGKDAGRL 

       610        620        630        640        650        660 
SAAWQLYKAQ EELIKVAKDF GVKLTMFHGR GGTVGRGGGP THLAILSQPP DTIHGSLRVT 

       670        680        690        700        710        720 
VQGEVIEQSF GEEHLSFRTL QRFTAATLEH GMHPPNAPKP EWRTLLDEMA VVATEEYRSI 

       730        740        750        760        770        780 
VFQEPRFVEY FRLATPETEY GRMNIGSRPS KRKPSGGIES LRAIPWIFAW TQTRFHLPVW 

       790        800        810        820        830        840 
LGFGGAFKHV LQKDIRNLHM LQEMYNEWPF FRVTIDLVEM VFAKGNPGIA ALYDKLLVSE 

       850        860        870        880        890        900 
ELRPLGEKLR ANYEETQKLL LQVAGHRDLL EGDPYLKQRL RLRDAYITTL NVCQAYTLKR 

       910        920        930        940        950        960 
IRDPDYHVAL RPHLSKEIMD PTKAASELVK LNPGSEYAPG LEDTLILTMK GIAAGLQNTG 

« Hide

References

[1]"Complete nucleotide sequence of one member of the Sorghum phosphoenolpyruvate carboxylase gene family."
Lepiniec L., Santi S., Keryer E., Amiet V., Vidal J., Gadal P., Cretin C.
Plant Mol. Biol. 17:1077-1079(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X59925 Genomic DNA. Translation: CAA42549.1.
PIRS18240.

3D structure databases

ProteinModelPortalP29194.
SMRP29194. Positions 26-960.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING4558.Sb02g021090.1.

Proteomic databases

PRIDEP29194.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

GrameneP29194.

Phylogenomic databases

eggNOGCOG2352.

Enzyme and pathway databases

UniPathwayUPA00321.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 2 hits.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAPP2_SORBI
AccessionPrimary (citable) accession number: P29194
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 1, 1992
Last modified: February 19, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways