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Protein

Transforming protein v-Fos/v-Fox

Gene

FOS-FOX

Organism
FBR murine osteosarcoma virus (FBR-MSV) (Finkel-Biskis-Reilly murine osteosarcoma virus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Miscellaneous

This protein is synthesized as a Gag-Fos-Fox polyprotein.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Transforming protein v-Fos/v-Fox
Gene namesi
Name:FOS-FOX
OrganismiFBR murine osteosarcoma virus (FBR-MSV) (Finkel-Biskis-Reilly murine osteosarcoma virus)
Taxonomic identifieri11806 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeGammaretrovirusunclassified Gammaretrovirus
Virus hostiMus musculus (Mouse) [TaxID: 10090]
Proteomesi
  • UP000237129 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Host nucleus

Pathology & Biotechi

Keywords - Diseasei

Oncogene

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000764611 – 244Transforming protein v-Fos/v-FoxAdd BLAST244

Structurei

3D structure databases

ProteinModelPortaliP29176
SMRiP29176
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini113 – 176bZIPPROSITE-ProRule annotationAdd BLAST64

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 236Transforming protein v-FosAdd BLAST236
Regioni115 – 135Basic motifPROSITE-ProRule annotationAdd BLAST21
Regioni141 – 169Leucine-zipperPROSITE-ProRule annotationAdd BLAST29
Regioni237 – 244Transforming protein v-Fox8

Sequence similaritiesi

Belongs to the bZIP family. Fos subfamily.Curated

Family and domain databases

InterProiView protein in InterPro
IPR000837 AP-1
IPR004827 bZIP
IPR029816 c-Fos/v-Fos
PANTHERiPTHR23351 PTHR23351, 2 hits
PTHR23351:SF4 PTHR23351:SF4, 2 hits
PfamiView protein in Pfam
PF00170 bZIP_1, 1 hit
PRINTSiPR00042 LEUZIPPRFOS
SMARTiView protein in SMART
SM00338 BRLZ, 1 hit
PROSITEiView protein in PROSITE
PS50217 BZIP, 1 hit
PS00036 BZIP_BASIC, 1 hit

Sequencei

Sequence statusi: Complete.

P29176-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
DSLSYYHSPA DSFSSMGSPV NTQDFCADLS VSSANFIPTE TAISTSPDLQ
60 70 80 90 100
WLVQPTLVSS VAPSQTRAPH PYGLPTQSAG AYARAGMVKT VSGGRAQSIG
110 120 130 140 150
RRGKVEQLSP EEEVKRRIRR ERNKMAAAKC RNRRRELTDT LQAETDQLED
160 170 180 190 200
EKSALQTEIA NLLKEKEKLE FILAAHRPAC KIPDDLGFPE EMSVASLDLT
210 220 230 240
GGLLPLLNDP EPKPSLEPVK SSFDDFLFPA SSGHSGFISM AGWQ
Length:244
Mass (Da):26,622
Last modified:December 1, 1992 - v1
Checksum:i95C904B66B0EB270
GO

Sequence cautioni

The sequence AAA46573 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K02712 Genomic DNA Translation: AAA46573.1 Different initiation.
PIRiB23244 TVMVFB

Similar proteinsi

Entry informationi

Entry nameiFOSX_MSVFR
AccessioniPrimary (citable) accession number: P29176
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 1, 1992
Last modified: May 23, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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