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Protein

MmsAB operon regulatory protein

Gene

mmsR

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Regulatory protein for the mmsAB operon. Activates the transcription of the mmsAB genes.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi217 – 236H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

  • positive regulation of cellular amino acid biosynthetic process Source: PseudoCAP
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
MmsAB operon regulatory proteinCurated
Gene namesi
Name:mmsR1 Publication
Ordered Locus Names:PA3571
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA3571.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001945391 – 307MmsAB operon regulatory proteinAdd BLAST307

Proteomic databases

PaxDbiP28809.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA3571.

Structurei

3D structure databases

ProteinModelPortaliP28809.
SMRiP28809.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG41063TF. Bacteria.
ENOG4111G16. LUCA.
HOGENOMiHOG000225868.
InParanoidiP28809.
OMAiPYEYLIR.
PhylomeDBiP28809.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
2.60.120.280. 1 hit.
InterProiView protein in InterPro
IPR003313. AraC-bd.
IPR009057. Homeobox-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR020449. Tscrpt_reg_HTH_AraC-type.
PfamiView protein in Pfam
PF02311. AraC_binding. 1 hit.
PF12833. HTH_18. 1 hit.
PRINTSiPR00032. HTHARAC.
SMARTiView protein in SMART
SM00342. HTH_ARAC. 1 hit.
SUPFAMiSSF46689. SSF46689. 2 hits.
SSF51215. SSF51215. 1 hit.
PROSITEiView protein in PROSITE
PS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.

Sequencei

Sequence statusi: Complete.

P28809-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDYIAEPATD MSHTSDWPLP ADSLRLPIPA ALLEKLAVHP LSRDLYPTSL
60 70 80 90 100
GHYRRARDHR MSRERHDEHL LIYCSEGQGL LRVREGEAWR EYRVGSGDLL
110 120 130 140 150
WLPPGMAHDY AADDRQPWTI FWTHLRGDSA TWLQHSAGYR DTPLRHWGLQ
160 170 180 190 200
HALLGGFEQL LEVRHSGYRF QHFLLAASRL RSLLCQLPLL RPLREGSLDL
210 220 230 240 250
DGLHAYMREH LHARLELERL AAFCNLSKFH FVSRYKAITG RTPIQHFLHL
260 270 280 290 300
KIEYACQLLD SSDQSVARVG QAVGYDDSYY FSRLFSKVMG LSPSAYRQRV

RQGEGGA
Length:307
Mass (Da):35,379
Last modified:December 8, 2000 - v2
Checksum:i9BF7AEE348FAFD45
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti129S → T in AAA25890 (PubMed:1339433).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M84911 Genomic DNA. Translation: AAA25890.1.
AE004091 Genomic DNA. Translation: AAG06959.1.
PIRiA42902.
F83198.
RefSeqiNP_252261.1. NC_002516.2.
WP_003122160.1. NZ_ASJY01000583.1.

Genome annotation databases

EnsemblBacteriaiAAG06959; AAG06959; PA3571.
GeneIDi878815.
KEGGipae:PA3571.
PATRICi19841759. VBIPseAer58763_3737.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M84911 Genomic DNA. Translation: AAA25890.1.
AE004091 Genomic DNA. Translation: AAG06959.1.
PIRiA42902.
F83198.
RefSeqiNP_252261.1. NC_002516.2.
WP_003122160.1. NZ_ASJY01000583.1.

3D structure databases

ProteinModelPortaliP28809.
SMRiP28809.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA3571.

Proteomic databases

PaxDbiP28809.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG06959; AAG06959; PA3571.
GeneIDi878815.
KEGGipae:PA3571.
PATRICi19841759. VBIPseAer58763_3737.

Organism-specific databases

PseudoCAPiPA3571.

Phylogenomic databases

eggNOGiENOG41063TF. Bacteria.
ENOG4111G16. LUCA.
HOGENOMiHOG000225868.
InParanoidiP28809.
OMAiPYEYLIR.
PhylomeDBiP28809.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
2.60.120.280. 1 hit.
InterProiView protein in InterPro
IPR003313. AraC-bd.
IPR009057. Homeobox-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR020449. Tscrpt_reg_HTH_AraC-type.
PfamiView protein in Pfam
PF02311. AraC_binding. 1 hit.
PF12833. HTH_18. 1 hit.
PRINTSiPR00032. HTHARAC.
SMARTiView protein in SMART
SM00342. HTH_ARAC. 1 hit.
SUPFAMiSSF46689. SSF46689. 2 hits.
SSF51215. SSF51215. 1 hit.
PROSITEiView protein in PROSITE
PS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMMSR_PSEAE
AccessioniPrimary (citable) accession number: P28809
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 8, 2000
Last modified: April 12, 2017
This is version 120 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.