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Protein

Uncharacterized fimbrial chaperone YhcA

Gene

yhcA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Could be required for the biogenesis of a putative fimbria.By similarity

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processFimbrium biogenesis

Enzyme and pathway databases

BioCyciEcoCyc:EG11515-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized fimbrial chaperone YhcA
Gene namesi
Name:yhcA
Ordered Locus Names:b3215, JW3182
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11515 yhcA

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_000000929520 – 224Uncharacterized fimbrial chaperone YhcAAdd BLAST205

Proteomic databases

PaxDbiP28722
PRIDEiP28722

Interactioni

Protein-protein interaction databases

BioGridi4259287, 6 interactors
IntActiP28722, 14 interactors
STRINGi316385.ECDH10B_3390

Structurei

3D structure databases

ProteinModelPortaliP28722
SMRiP28722
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the periplasmic pilus chaperone family.Curated

Keywords - Domaini

Immunoglobulin domain, Signal

Phylogenomic databases

eggNOGiENOG4108S1B Bacteria
ENOG4111FTJ LUCA
HOGENOMiHOG000260652
OMAiLPHAWIL
PhylomeDBiP28722

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR013783 Ig-like_fold
IPR008962 PapD-like_sf
IPR036316 Pili_assmbl_chap_C_dom_sf
IPR016147 Pili_assmbl_chaperone_N
PfamiView protein in Pfam
PF00345 PapD_N, 1 hit
SUPFAMiSSF49354 SSF49354, 1 hit
SSF49584 SSF49584, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P28722-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRHITFTVF ITTSMNTLAT GMVPETSVLL VDEKRGEASI NIKNTDDHPS
60 70 80 90 100
LLYTTIVDLP ESNKSIRLIP TQPVIRVEAG QVQQVRFLLQ ATVPLQSEEL
110 120 130 140 150
KRVTFEGIPP KDDKSSRVTV SIRQDLPVLI HPASLPEERE TWKFLEWRKN
160 170 180 190 200
GDQIEISNPS NYVVRMTLQF KTLPSGKTGA INKTYFLPHT STTTALTNAT
210 220
DTKVEFYPAS RYGYRGNKYV TDLK
Length:224
Mass (Da):25,339
Last modified:November 1, 1995 - v2
Checksum:iCFD7E170E7C99684
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti24 – 58PETSV…TTIVD → LKHQYCWLMKSVVKLVLILR IQMIILHCFTPPLLI (PubMed:1447980).CuratedAdd BLAST35
Sequence conflicti204 – 224VEFYP…VTDLK → GRVLPSQPIWLSR in AAA23910 (PubMed:1447980).CuratedAdd BLAST21

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M74162 Genomic DNA Translation: AAA23910.1
U18997 Genomic DNA Translation: AAA58017.1
U00096 Genomic DNA Translation: AAC76247.1
AP009048 Genomic DNA Translation: BAE77259.1
PIRiA65113
RefSeqiNP_417682.1, NC_000913.3
WP_001311157.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76247; AAC76247; b3215
BAE77259; BAE77259; BAE77259
GeneIDi947741
KEGGiecj:JW3182
eco:b3215
PATRICifig|1411691.4.peg.3514

Similar proteinsi

Entry informationi

Entry nameiYHCA_ECOLI
AccessioniPrimary (citable) accession number: P28722
Secondary accession number(s): Q2M8Z7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: November 1, 1995
Last modified: March 28, 2018
This is version 132 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health