Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein GltF

Gene

gltF

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in induction of the so-called NTR enzymes in response to nitrogen deprivation, as well as in glutamate biosynthesis. May mediate the glutamate-dependent repression of the GLT operon.

Enzyme and pathway databases

BioCyciEcoCyc:EG11514-MONOMER.
ECOL316407:JW3181-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein GltF
Gene namesi
Name:gltF
Ordered Locus Names:b3214, JW3181
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11514. gltF.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei213 – 22917HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525Sequence analysisAdd
BLAST
Chaini26 – 254229Protein GltFPRO_0000021335Add
BLAST

Proteomic databases

PaxDbiP28721.
PRIDEiP28721.

Expressioni

Inductioni

Repressed by H-NS, induced by LeuO. A monocistronic operon.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4262941. 9 interactions.
IntActiP28721. 3 interactions.
STRINGi511145.b3214.

Structurei

3D structure databases

ProteinModelPortaliP28721.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

To E.coli YhcF.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4106AJS. Bacteria.
ENOG410Y11X. LUCA.
InParanoidiP28721.
OMAiTINCSAP.

Family and domain databases

InterProiIPR010546. DUF1120.
[Graphical view]
PfamiPF06551. DUF1120. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P28721-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFFKKNLTTA AICAALSVAA FSAMATDSTD TELTIIGEYT PGACTPVVTG
60 70 80 90 100
GGIVDYGKHH NSALNPTGKS NKLVQLGRKN STLNITCTAP TLIAVTSKDN
110 120 130 140 150
RQSTIVALND TSYIEKAYDT LVDMKGTKNA FGLGSAPNGQ KIGAASIGID
160 170 180 190 200
RSNGGIHAAD DTGEIPVDLI QTDHWSAATP TWKASSNGAF CSLTSCSAIE
210 220 230 240 250
RGYSVAKTGE LTPVAITAVT FPLLIDAAVN DNTILGSDET IKLDGNVTIS

VQYL
Length:254
Mass (Da):26,352
Last modified:December 1, 1992 - v1
Checksum:i7424D7D1339A5F27
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M74162 Genomic DNA. Translation: AAA23909.1.
U18997 Genomic DNA. Translation: AAA58016.1.
U00096 Genomic DNA. Translation: AAC76246.1.
AP009048 Genomic DNA. Translation: BAE77258.1.
PIRiS25281.
RefSeqiNP_417681.1. NC_000913.3.
WP_000465371.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76246; AAC76246; b3214.
BAE77258; BAE77258; BAE77258.
GeneIDi947746.
KEGGiecj:JW3181.
eco:b3214.
PATRICi32121850. VBIEscCol129921_3309.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M74162 Genomic DNA. Translation: AAA23909.1.
U18997 Genomic DNA. Translation: AAA58016.1.
U00096 Genomic DNA. Translation: AAC76246.1.
AP009048 Genomic DNA. Translation: BAE77258.1.
PIRiS25281.
RefSeqiNP_417681.1. NC_000913.3.
WP_000465371.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP28721.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262941. 9 interactions.
IntActiP28721. 3 interactions.
STRINGi511145.b3214.

Proteomic databases

PaxDbiP28721.
PRIDEiP28721.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76246; AAC76246; b3214.
BAE77258; BAE77258; BAE77258.
GeneIDi947746.
KEGGiecj:JW3181.
eco:b3214.
PATRICi32121850. VBIEscCol129921_3309.

Organism-specific databases

EchoBASEiEB1476.
EcoGeneiEG11514. gltF.

Phylogenomic databases

eggNOGiENOG4106AJS. Bacteria.
ENOG410Y11X. LUCA.
InParanoidiP28721.
OMAiTINCSAP.

Enzyme and pathway databases

BioCyciEcoCyc:EG11514-MONOMER.
ECOL316407:JW3181-MONOMER.

Miscellaneous databases

PROiP28721.

Family and domain databases

InterProiIPR010546. DUF1120.
[Graphical view]
PfamiPF06551. DUF1120. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGLTF_ECOLI
AccessioniPrimary (citable) accession number: P28721
Secondary accession number(s): Q2M8Z8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 1, 1992
Last modified: September 7, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.