P28711 (VP2_FCVF9) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein VP2

Alternative name(s):
Minor capsid protein

Gene names

ORF Names:

ORF3

Organism

Feline calicivirus (strain F9) (FCV) [Complete proteome]

Taxonomic identifier

11981 [NCBI]

Taxonomic lineage

Viruses › ssRNA viruses › ssRNA positive-strand viruses, no DNA stage › Caliciviridae › Vesivirus › Feline calicivirus

Virus host

Felidae (cat family) [TaxID: 9681]

Protein attributes

Sequence length	106 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Minor structural protein present in one or two copies per virion. Does not seem to play a role in capsid assembly, but is essential for production of infectious virus By similarity.
Subunit structure	May interact with capsid protein By similarity.
Subcellular location	Virion. Host cytoplasm By similarity.
Miscellaneous	Translated by a ribosomal terminaition-reinitiation process from the bicistronic mRNA encoding for VP1 and VP2.
Sequence similarities	Belongs to the vesivirus VP2 protein family.

Ontologies

Keywords
Cellular component	Host cytoplasm Virion
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	host cell cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell virion Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 106	106	Protein VP2		PRO_0000100124

Sequences

	Sequence		Length	Mass (Da)
	P28711 [UniParc]. Last modified December 1, 1992. Version 1. Checksum: 6CC14546564D75E5	FASTA	106	12,095
	10 20 30 40 50 60 MNSILGLIDT VTNTIGKAQQ IELDKAALGQ QRELALQRIG LDRQALNNQV EQFNKILEQR 70 80 90 100 VQGPIQSVRL ARAAGFRVDP YSYTNQNFYD DQLNAIRLSY KNLFKI

References

[1]	"The complete nucleotide sequence of a feline calicivirus." Carter M.J., Milton I.D., Meanger J., Bennett M., Gaskell R.M., Turner P.C. Virology 190:443-448(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[2]	"Cloning and sequence determination of the feline calicivirus strain F9." Meanger J., Carter M.J., Gaskell R.M., Turner P.C. Biochem. Soc. Trans. 20:26S-26S(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[3]	"Identification and sequence determination of the capsid protein gene of feline calicivirus." Carter M.J., Milton I.D., Turner P.C., Meanger J., Bennett M., Gaskell R.M. Arch. Virol. 122:223-235(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[4]	"The mechanism of an exceptional case of reinitiation after translation of a long ORF reveals why such events do not generally occur in mammalian mRNA translation." Poyry T.A., Kaminski A., Connell E.J., Fraser C.S., Jackson R.J. Genes Dev. 21:3149-3162(2007) [PubMed] [Europe PMC] [Abstract] Cited for: EXPRESSION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M86379 Genomic RNA. No translation available. Z11536 Genomic RNA. Translation: CAA77638.1.
PIR	C43382.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR007996. Vesivirus_VP2. [Graphical view]
Pfam	PF05332. DUF743. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

VP2_FCVF9

Accession

Primary (citable) accession number: P28711

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 1992
Last sequence update:	December 1, 1992
Last modified:	April 3, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program