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Protein

3-oxoacyl-[acyl-carrier-protein] reductase, chloroplastic

Gene

CLKR27

Organism
Cuphea lanceolata (Cigar flower)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP+ = 3-oxoacyl-[acyl-carrier-protein] + NADPH.

Pathwayi: fatty acid biosynthesis

This protein is involved in the pathway fatty acid biosynthesis, which is part of Lipid metabolism.
View all proteins of this organism that are known to be involved in the pathway fatty acid biosynthesis and in Lipid metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei214SubstrateBy similarity1
Active sitei227Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi82 – 106NADPBy similarityAdd BLAST25

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processFatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism
LigandNADP

Enzyme and pathway databases

UniPathwayiUPA00094

Names & Taxonomyi

Protein namesi
Recommended name:
3-oxoacyl-[acyl-carrier-protein] reductase, chloroplastic (EC:1.1.1.100)
Alternative name(s):
3-ketoacyl-acyl carrier protein reductase
Gene namesi
Name:CLKR27
OrganismiCuphea lanceolata (Cigar flower)
Taxonomic identifieri3930 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsMyrtalesLythraceaeCuphea

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 61ChloroplastBy similarityAdd BLAST61
ChainiPRO_000003198162 – 3203-oxoacyl-[acyl-carrier-protein] reductase, chloroplasticAdd BLAST259

Proteomic databases

PRIDEiP28643

Interactioni

Subunit structurei

Homotetramer.Curated

Structurei

3D structure databases

ProteinModelPortaliP28643
SMRiP28643
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Family and domain databases

InterProiView protein in InterPro
IPR011284 3oxo_ACP_reduc
IPR036291 NAD(P)-bd_dom_sf
IPR020904 Sc_DH/Rdtase_CS
IPR002347 SDR_fam
PRINTSiPR00081 GDHRDH
PR00080 SDRFAMILY
SUPFAMiSSF51735 SSF51735, 1 hit
TIGRFAMsiTIGR01830 3oxo_ACP_reduc, 1 hit
PROSITEiView protein in PROSITE
PS00061 ADH_SHORT, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P28643-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATATAAGCS GAVALKSLGG RRLCIPQQLS PVLAGFGSHA AKSFPILSTR
60 70 80 90 100
SIATSGIRAQ VATAEKVSAG AGQSVESPVV IVTGASRGIG KAIALSLGKA
110 120 130 140 150
GCKVLVNYAR SSKEAEEVSK EIEAFGGQAL TFGGDVSKEE DVEAMIKTAV
160 170 180 190 200
DAWGTVDILV NNAGITRDGL LMRMKKSQWQ EVIDLNLTGV FLCTQAAAKI
210 220 230 240 250
MMKKKKGRII NIASVVGLVG NAGQANYSAA KAGVIGFTKT VAREYASRNI
260 270 280 290 300
NVNAVAPGFI SSDMTSKLGD DINKKILETI PLGRYGQPEE VAGLVEFLAI
310 320
NPASSYVTGQ VFTIDGGMTM
Length:320
Mass (Da):33,103
Last modified:December 1, 1992 - v1
Checksum:i06BAF0522B2B8C87
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X64566 mRNA Translation: CAA45866.1
PIRiS22450

Similar proteinsi

Entry informationi

Entry nameiFABG_CUPLA
AccessioniPrimary (citable) accession number: P28643
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 1, 1992
Last modified: May 23, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health