P28626 (YIM2_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative uncharacterized protein YIM2

Alternative name(s):
RF435

Gene names

Name:	YIM2
Ordered Locus Names:	YMR151W
ORF Names:	YM9375.21

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	145 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Subcellular location	Membrane; Multi-pass membrane protein Potential.
Caution	Product of a dubious gene prediction. Partially overlaps IMP1.
Sequence caution	The sequence AAB19703.1 differs from that shown. Reason: Frameshift at positions 118 and 131.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 145	145	Putative uncharacterized protein YIM2		PRO_0000203309
Regions
	Transmembrane	20 – 40	21	Helical; Potential
	Transmembrane	116 – 136	21	Helical; Potential
Experimental info
	Sequence conflict	39	1	F → L in AAB19703. Ref.1
	Sequence conflict	83	1	K → E in AAB19703. Ref.1
	Sequence conflict	115	1	Y → H in AAB19703. Ref.1
	Sequence conflict	132	1	C → F in AAB19703. Ref.1
	Sequence conflict	143	1	F → S in AAB19703. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P28626 [UniParc]. Last modified February 1, 1995. Version 2. Checksum: 4FA50339CCF33BE8	FASTA	145	16,851
	10 20 30 40 50 60 MGSVPTVIPG IVHCWMIHCL IGPFLFAIIY WSIFIEGMFF PQKYLDCQSV INLLCGSNQQ 70 80 90 100 110 120 KRIFKEKLRI YQVHIQEKIG CSKFNTLLLI YQLGSRHKIN RQINDLLCNL CSKNYMIMLL 130 140 YAEIIIYSSF SCVLSATIFL RGFLL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Mitochondrial inner membrane protease 1 of Saccharomyces cerevisiae shows sequence similarity to the Escherichia coli leader peptidase." Behrens M., Michaelis G., Pratje E. Mol. Gen. Genet. 228:167-176(1991) [PubMed: 1886606] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII." Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. , Skelton J., Walsh S.V., Whitehead S., Barrell B.G. Nature 387:90-93(1997) [PubMed: 9169872] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[3]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	S55518 Genomic DNA. Translation: AAB19703.1. Frameshift. Z47071 Genomic DNA. Translation: CAA87366.1. AY558119 Genomic DNA. Translation: AAS56445.1.
PIR	S50408.
3D structure databases
ProteinModelPortal	P28626.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-4406N.
MINT	MINT-508455.
STRING	P28626.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YMR151W; YMR151W; YMR151W.
Organism-specific databases
SGD	S000004759. YIM2.
Phylogenomic databases
eggNOG	fuNOG12870.
Gene expression databases
ArrayExpress	P28626.
Genevestigator	P28626.
GermOnline	YMR151W. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

YIM2_YEAST

Accession

Primary (citable) accession number: P28626

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 1992
Last sequence update:	February 1, 1995
Last modified:	September 21, 2011
This is version 70 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program