Reviewed,
UniProtKB/Swiss-Prot P28625 (YM27_YEAST)
Last modified
November 24, 2009.
Version 84.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Uncharacterized protein YMR152W | ||||
| Gene names |
| ||||
| Organism | Saccharomyces cerevisiae (Baker's yeast) [Complete proteome] | ||||
| Taxonomic identifier | 4932 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 365 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Subcellular location | Membrane; Single-pass membrane protein Potential. |
| Miscellaneous | Present with 6540 molecules/cell in log phase SD medium. Ref.4 |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Membrane |
| Domain | Transmembrane |
| PTM | Phosphoprotein |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | oxidation reduction Inferred from electronic annotation. Source: InterPro response to DNA damage stimulusInferred from mutant phenotype. Source: SGD |
| Cellular component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell lipid particleInferred from direct assay. Source: SGD mitochondrionInferred from direct assay. Source: SGD |
| Molecular function | oxidoreductase activity Inferred from electronic annotation. Source: InterPro protein bindingInferred from physical interaction. Source: IntAct zinc ion bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Binary interactions
With | Entry | #Exp. | IntAct | Notes |
|---|---|---|---|---|
| SLC1 | P33333 | 1 | EBI-27313,EBI-13494 | |
| SNA3 | P14359 | 1 | EBI-27313,EBI-26122 | |
| SSE1 | P32589 | 1 | EBI-27313,EBI-8648 | |
| TGL1 | P34163 | 1 | EBI-27313,EBI-19177 |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 365 | 365 | Uncharacterized protein YMR152W | PRO_0000203310 | |||||
Regions | |||||||||
| Transmembrane | 140 – 158 | 19 | Potential | ||||||
Amino acid modifications | |||||||||
| Modified residue | 25 | 1 | Phosphoserine Ref.5 | ||||||
Experimental info | |||||||||
| Sequence conflict | 121 | 1 | V → I in AAB19702. Ref.1 | ||||||
| Sequence conflict | 234 | 1 | S → I in AAB19702. Ref.1 | ||||||
| Sequence conflict | 280 | 1 | D → N in AAB19702. Ref.1 | ||||||
| Sequence conflict | 296 | 1 | L → S in AAB19702. Ref.1 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Mitochondrial inner membrane protease 1 of Saccharomyces cerevisiae shows sequence similarity to the Escherichia coli leader peptidase." Behrens M., Michaelis G., Pratje E. Mol. Gen. Genet. 228:167-176(1991) [PubMed: 1886606] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [2] | "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII." Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. Barrell B.G.Nature 387:90-93(1997) [PubMed: 9169872] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972. |
| [3] | "Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. LaBaer J.Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c. |
| [4] | "Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]. |
| [5] | "A multidimensional chromatography technology for in-depth phosphoproteome analysis." Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H. Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-25, MASS SPECTROMETRY. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| S55518 Genomic DNA. Translation: AAB19702.1. Z47071 Genomic DNA. Translation: CAA87367.1. Z49705 Genomic DNA. Translation: CAA89788.1. AY558419 Genomic DNA. Translation: AAS56745.1. | |
| PIR | S50409. |
| RefSeq | NP_013872.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| DIP | DIP:4467N. |
| IntAct | P28625. 7 interactions. |
| STRING | P28625. |
Genome annotation databases | |
| Ensembl | YMR152W; YMR152W; YMR152W; Saccharomyces cerevisiae. [Genome view] |
| GeneID | 855183. |
| KEGG | sce:YMR152W. |
| NMPDR | fig|4932.3.peg.4922. |
Organism-specific databases | |
| CYGD | YMR152w. |
| SGD | S000004760. YIM1. |
Phylogenomic databases | |
| HOGENOM | P28625. |
| OMA | IDSVYEF |
| OrthoDB | EOG95HTDH |
Gene expression databases | |
| ArrayExpress | P28625. |
| Genevestigator | P28625. |
| GermOnline | YMR152W. Saccharomyces cerevisiae. |
Family and domain databases | |
| InterPro | IPR013154. ADH_GroES-like. IPR002085. ADH_SF_Zn. IPR011032. GroES-like. IPR016040. NAD(P)-bd_dom. [Graphical view] |
| Gene3D | G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. |
| PANTHER | PTHR11695. ADH_Sf_Zn. 1 hit. |
| Pfam | PF08240. ADH_N. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 978641. |
Entry information
| Entry name | YM27_YEAST | ||||||||
| Accession | Primary (citable) accession number: P28625 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
| Yeast chromosome XIII Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names |

Clusters with


