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P28581

- PHOC_MORMO

UniProt

P28581 - PHOC_MORMO

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Protein

Major phosphate-irrepressible acid phosphatase

Gene

phoC

Organism
Morganella morganii (Proteus morganii)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

pH dependencei

Optimum pH is about 6.

GO - Molecular functioni

  1. acid phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Major phosphate-irrepressible acid phosphatase (EC:3.1.3.2)
Short name:
HPAP
Gene namesi
Name:phoC
OrganismiMorganella morganii (Proteus morganii)
Taxonomic identifieri582 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeMorganella

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
  2. outer membrane-bounded periplasmic space Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 20201 PublicationAdd
BLAST
Chaini21 – 249229Major phosphate-irrepressible acid phosphatasePRO_0000023999Add
BLAST

Interactioni

Subunit structurei

Homotetramer.

Structurei

3D structure databases

ProteinModelPortaliP28581.
SMRiP28581. Positions 25-245.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

Gene3Di1.20.144.10. 1 hit.
InterProiIPR011158. Acid_Pase_ClassA.
IPR001011. Acid_Pase_classA_bac.
IPR018296. Acid_Pase_classA_bac_CS.
IPR000326. P_Acid_Pase_2/haloperoxidase.
[Graphical view]
PfamiPF01569. PAP2. 1 hit.
[Graphical view]
PIRSFiPIRSF000897. Acid_Ptase_ClsA. 1 hit.
PRINTSiPR00483. BACPHPHTASE.
SMARTiSM00014. acidPPc. 1 hit.
[Graphical view]
SUPFAMiSSF48317. SSF48317. 1 hit.
PROSITEiPS01157. ACID_PHOSPH_CL_A. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P28581-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKKNIIAGCL FSLFSLSALA AIPAGNDATT KPDLYYLKNE QAIDSLKLLP
60 70 80 90 100
PPPEVGSIQF LNDQAMYEKG RMLRNTERGK QAQADADLAA GGVATAFSGA
110 120 130 140 150
FGYPITEKDS PELYKLLTNM IEDAGDLATR SAKEHYMRIR PFAFYGTETC
160 170 180 190 200
NTKDQKKLST NGSYPSGHTS IGWATALVLA EVNPANQDAI LERGYQLGQS
210 220 230 240
RVICGYHWQS DVDAARIVGS AAVATLHSDP AFQAQLAKAK QEFAQKSQK
Length:249
Mass (Da):26,999
Last modified:December 1, 1992 - v1
Checksum:iC43F3698052B6A5C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X64444 Genomic DNA. Translation: CAA45774.1.
AB035805 Genomic DNA. Translation: BAA96744.1.
PIRiS19187.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X64444 Genomic DNA. Translation: CAA45774.1 .
AB035805 Genomic DNA. Translation: BAA96744.1 .
PIRi S19187.

3D structure databases

ProteinModelPortali P28581.
SMRi P28581. Positions 25-245.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 1.20.144.10. 1 hit.
InterProi IPR011158. Acid_Pase_ClassA.
IPR001011. Acid_Pase_classA_bac.
IPR018296. Acid_Pase_classA_bac_CS.
IPR000326. P_Acid_Pase_2/haloperoxidase.
[Graphical view ]
Pfami PF01569. PAP2. 1 hit.
[Graphical view ]
PIRSFi PIRSF000897. Acid_Ptase_ClsA. 1 hit.
PRINTSi PR00483. BACPHPHTASE.
SMARTi SM00014. acidPPc. 1 hit.
[Graphical view ]
SUPFAMi SSF48317. SSF48317. 1 hit.
PROSITEi PS01157. ACID_PHOSPH_CL_A. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Characterization and sequence of PhoC, the principal phosphate-irrepressible acid phosphatase of Morganella morganii."
    Thaller M.C., Berlutti F., Schippa S., Lombardi G., Rossolini G.M.
    Microbiology 140:1341-1350(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 21-40.
    Strain: RS12.
  2. "Phosphorylation of nucleosides by the mutated acid phosphatase from Morganella morganii."
    Mihara Y., Utagawa T., Yamada H., Asano Y.
    Appl. Environ. Microbiol. 66:2811-2816(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 8019 / CCM 680 / DSM 30117 / NCIMB 10466.

Entry informationi

Entry nameiPHOC_MORMO
AccessioniPrimary (citable) accession number: P28581
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 1, 1992
Last modified: October 1, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3