Reviewed, UniProtKB/Swiss-Prot P28567 (CDC22_PEA)

Names and origin

Protein names	Recommended name:     Cell division control protein 2 homolog 2     EC=2.7.11.22     EC=2.7.11.23
Organism	Pisum sativum (Garden pea)
Taxonomic identifier	3888 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids I › Fabales › Fabaceae › Papilionoideae › Fabeae › Pisum

Protein attributes

Sequence length	151 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein. ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.
Sequence similarities	Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. Contains 1 protein kinase domain.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase Transferase
Gene Ontology (GO)
Biological process	protein amino acid phosphorylation Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW RNA polymerase subunit kinase activity Inferred from electronic annotation. Source: EC cyclin-dependent protein kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›151	›151	Cell division control protein 2 homolog 2		PRO_0000085758
Regions
	Domain	‹1 – ›151	›151	Protein kinase
Sites
	Active site	113	1	Proton acceptor By similarity
	Binding site	3	1	ATP By similarity
Experimental info
	Non-terminal residue	1	1
	Non-terminal residue	151	1

Sequences

	Sequence		Length	Mass (Da)
	P28567-1 [UniParc]. Last modified December 1, 1992. Version 1. Checksum: E29AFBA3E0641479	FASTA	151	17,463
	10 20 30 40 50 60 ALKEIRMDNE REGFPITAIR EIKILKKLHH ENVIKLKEIV TSPGPEKDDQ GRPDGNKYKR 70 80 90 100 110 120 LAIYMVFEYM DHDLTGLADR PGMRFTVPQI KCYMRQLLTG LHYCHVNQVL HRDIKGSNLL 130 140 150 IDNEGNLKLA DFGLARSFSN EIMQTLQIES L

References

[1]	"Cloning of the pea cdc2 homologue by efficient immunological screening of PCR products." Feiler H.S., Jacobs T.W. Plant Mol. Biol. 17:321-333(1991) [PubMed: 1883993] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Alaska.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X56554 mRNA. Translation: CAA39904.1.
PIR	S17451.
3D structure databases
HSSP	HSSP built from PDB template 1H1R based on UniProtKB P24941.
ModBase	Search...
Enzyme and pathway databases
BRENDA	2.7.11.22. 287. 2.7.11.23. 287.
Family and domain databases
InterPro	IPR000719. Prot_kinase_core. IPR017441. Protein_kinase_ATP_BS. IPR017442. Se/Thr_pkinase-rel. IPR008271. Ser_thr_pkin_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
ProDom	PD000001. Prot_kinase. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00107. PROTEIN_KINASE_ATP. Partial match. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CDC22_PEA

Accession

Primary (citable) accession number: P28567

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 1992
Last sequence update:	December 1, 1992
Last modified:	June 16, 2009
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)