Reviewed, UniProtKB/Swiss-Prot P28485 (ADHR_DROER)

Names and origin

Protein names

Recommended name:
    Alcohol dehydrogenase-related 31 kDa protein

Gene names

Name:	Adhr
Synonyms:	Adh-dup

Organism

Drosophila erecta (Fruit fly)

Taxonomic identifier

7220 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	202 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	alcohol dehydrogenase activity Inferred from electronic annotation. Source: InterPro binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›202	›202	Alcohol dehydrogenase-related 31 kDa protein		PRO_0000054503
Regions
	Nucleotide binding	11 – 34	24	NAD or NADP By similarity
Sites
	Active site	152	1	Proton acceptor By similarity
	Binding site	139	1	Substrate By similarity
Experimental info
	Non-terminal residue	202	1

Sequences

	Sequence		Length	Mass (Da)
	P28485-1 [UniParc]. Last modified December 1, 1992. Version 1. Checksum: 712696BB6DE16F12	FASTA	202	22,111
	10 20 30 40 50 60 MFDLTGKHVC YVADCGGIAL ETSKVLMTKN IAKLAILQSL ENPQAIAQLQ SIKPSTQIFF 70 80 90 100 110 120 WTYDVTMARE EMKKYFDEVM VQMDYIDVLI NGATLCDENN IDATINTNLT GMMNTVATVL 130 140 150 160 170 180 PHMDRKMGGS GGLIVNVTSV IGLDPSPVFC AYSASKFGVI GFTRSLADPL YYSQNGVAVM 190 200 AVCCGPTRVF VDRELKAFLE YG

References

[1]

"The molecular evolution of the alcohol dehydrogenase and alcohol dehydrogenase-related genes in the Drosophila melanogaster species subgroup." Jeffs P.S., Holmes E.C., Ashburner M. Mol. Biol. Evol. 11:287-304(1994) [PubMed: 8170369] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Gif-sur-Yvette stock 154.1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X54116 Genomic DNA. Translation: CAA38058.1.
3D structure databases
HSSP	HSSP built from PDB template 1B16 based on UniProtKB P10807.
ModBase	Search...
Organism-specific databases
FlyBase	FBgn0012262. Dere\Adhr.
Family and domain databases
InterPro	IPR002427. ADH-rel. IPR002198. DH_sc/Rdtase_SDR. IPR002424. Insect_AlcDH_fam. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PANTHER	PTHR19410. ADH_short_C2. 1 hit.
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PRINTS	PR01170. ADHRELATED. PR01167. INSADHFAMILY. PR00080. SDRFAMILY.
PROSITE	PS00061. ADH_SHORT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ADHR_DROER

Accession

Primary (citable) accession number: P28485

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 1992
Last sequence update:	December 1, 1992
Last modified:	June 16, 2009
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Drosophila annotation project