P28478 (P69_TYMVC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: 69 kDa protein Alternative name(s): p69
Organism	Turnip yellow mosaic virus (isolate TYMC)
Taxonomic identifier	31751 [NCBI]
Taxonomic lineage	Viruses › ssRNA positive-strand viruses, no DNA stage › Tymovirales › Tymoviridae › Tymovirus
Virus host	Brassica [TaxID: 3705] Cardamine lilacina [TaxID: 82359] Malva parviflora (Little mallow) (Cheeseweed mallow) [TaxID: 145753]

Protein attributes

Sequence length	628 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs By similarity.
Sequence similarities	Belongs to the tymoviridae protein p69 family.

Ontologies

Keywords
Molecular function	Suppressor of RNA silencing
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 628	628	69 kDa protein		PRO_0000222945

Sequences

	Sequence		Length	Mass (Da)
	P28478 [UniParc]. Last modified December 1, 1992. Version 1. Checksum: 0DF0C64E8ECBC6DC	FASTA	628	69,057
	10 20 30 40 50 60 MSNGLPISIG RPCTHDSQRS LSAPNSRIHS GFNSLLDTDL PMVHSEGTST PTQLLRHPNI 70 80 90 100 110 120 WFGNLPPPPR RPQDNRDFSP LHPLVFPGHH SQLRHVHETQ QVQQTCPGKL KLSGAEELPP 130 140 150 160 170 180 APQRQHSLPL HITRPSRFPH HFHARRPDVL PSVPDHGPVL AETKPRTSVR QPRSATRGPS 190 200 210 220 230 240 FRPILLPKVV HVHDDPPHSS LRPRGSRSRQ LQPTVRRPLL APNQFHSPRQ PPPLSDDPGI 250 260 270 280 290 300 LGPRPLAPNS TRDPPPRPIT PGPSNTHGLR PLSVLPRASP RRGLLPNPRR HRTSTGHIPP 310 320 330 340 350 360 TTTSRPTGPP SRLQRPVHLY QSSPHTPNFR PSSIRKDALL QTGPRLGHLE CLGQPANLRT 370 380 390 400 410 420 SERSPPTKRR LPRSSEPNRL PKPLPEATLA PSYRHRRSYP FLPNPPAALP SIAYTSSRGK 430 440 450 460 470 480 IHHSLPKGAL PKEGAPPPPR RLPSPAPHPQ LPLRDLGRTP GFPTPPKTPT RTPESRITAS 490 500 510 520 530 540 PTDIAPLDSD PVLSVRTEVH APERRTFMDP EALRSALASL PSPPRSVGII HTAPQTVLPA 550 560 570 580 590 600 NPPSPTRHLP PTSPPWILQS PVGEDAIVDS EDDSISSFYS HDFDSPSGPL RSQSPSRFRL 610 620 YLRSPSTSSG IEPWSPASYD YGSAPDTD

References

[1]	"Genomic RNA sequence of turnip yellow mosaic virus isolate TYMC, a cDNA-based clone with verified infectivity." Dreher T.W., Bransom K.L. Plant Mol. Biol. 18:403-406(1992) [PubMed: 1731998] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	X16378 Genomic RNA. Translation: CAA34414.1.
PIR	S19150.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR004935. 45/70kDa_tymoviral. [Graphical view]
Pfam	PF03251. Tymo_45kd_70kd. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P69_TYMVC

Accession

Primary (citable) accession number: P28478

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 1992
Last sequence update:	December 1, 1992
Last modified:	October 5, 2010
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program