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Protein

Putative peptide chain release factor homolog

Gene

prfH

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein uncertaini

Functioni

Could be involved in translational termination.

Caution

Could be the product of a pseudogene.Curated

GO - Molecular functioni

Keywordsi

Biological processProtein biosynthesis

Enzyme and pathway databases

BioCyciEcoCyc:EG11496-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative peptide chain release factor homolog
Short name:
RF-H
Gene namesi
Name:prfH
Ordered Locus Names:b0236, JW0226
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11496 prfH

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001668571 – 166Putative peptide chain release factor homologAdd BLAST166

Proteomic databases

PRIDEiP28369

Interactioni

Protein-protein interaction databases

BioGridi4259764, 22 interactors
IntActiP28369, 1 interactor
STRINGi316407.85674391

Structurei

3D structure databases

ProteinModelPortaliP28369
SMRiP28369
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi129 – 132Poly-Gln4

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4108S2Y Bacteria
COG1186 LUCA
HOGENOMiHOG000117078
InParanoidiP28369
KOiK02839
OMAiHKRKNWF
PhylomeDBiP28369

Family and domain databases

InterProiView protein in InterPro
IPR000352 Pep_chain_release_fac_I_II
IPR017509 Release_fac_PrfH
PANTHERiPTHR43804:SF5 PTHR43804:SF5, 1 hit
PfamiView protein in Pfam
PF00472 RF-1, 1 hit
TIGRFAMsiTIGR03072 release_prfH, 1 hit
PROSITEiView protein in PROSITE
PS00745 RF_PROK_I, 1 hit

Sequencei

Sequence statusi: Complete.

P28369-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLETETGRYS DTLRSALVSL DGDNAWALSE SWCGTIQWIC PSPYRPHHGR
60 70 80 90 100
KNWFLGIGRF TADEQEQSDA IRYETLRSSG PGGQHVNKTD SAVRATHLAS
110 120 130 140 150
GISVKVQSER SQHANKRLAR LLIAWKLEQQ QQENSAALKS QRRMFHHQIE
160
RGNPRRTFTG MAFIEG
Length:166
Mass (Da):18,834
Last modified:September 19, 2006 - v2
Checksum:i7555352297B51280
GO

Sequence cautioni

The sequence M34034 differs from that shown. Reason: Frameshift at position 32.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M34034 Unassigned DNA No translation available.
U70214 Genomic DNA Translation: AAB08656.1
U00096 Genomic DNA No translation available.
AP009048 Genomic DNA Translation: BAA77905.2
PIRiE64748

Genome annotation databases

EnsemblBacteriaiBAA77905; BAA77905; BAA77905
KEGGiecj:JW0226
PATRICifig|83333.103.peg.987

Similar proteinsi

Entry informationi

Entry nameiRFH_ECOLI
AccessioniPrimary (citable) accession number: P28369
Secondary accession number(s): P77246
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: September 19, 2006
Last modified: March 28, 2018
This is version 121 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health