Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P28342

- GSTZ1_DIACA

UniProt

P28342 - GSTZ1_DIACA

Protein

Glutathione S-transferase 1

Gene

GST1

Organism
Dianthus caryophyllus (Carnation) (Clove pink)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 Dec 1992)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

    Catalytic activityi

    RX + glutathione = HX + R-S-glutathione.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei60 – 601Glutathione; via amide nitrogen and carbonyl oxygenBy similarity
    Binding sitei112 – 1121GlutathioneBy similarity

    GO - Molecular functioni

    1. glutathione transferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. aromatic amino acid family metabolic process Source: InterPro

    Keywords - Molecular functioni

    Transferase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutathione S-transferase 1 (EC:2.5.1.18)
    Alternative name(s):
    GST class-zeta
    SR8
    Gene namesi
    Name:GST1
    Synonyms:CARSR8
    OrganismiDianthus caryophyllus (Carnation) (Clove pink)
    Taxonomic identifieri3570 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeCaryophyllalesCaryophyllaceaeDianthus

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 221221Glutathione S-transferase 1PRO_0000186031Add
    BLAST

    Expressioni

    Developmental stagei

    Senescing flowers.

    Inductioni

    Accumulates in response to the phytohormone ethylene.

    Structurei

    3D structure databases

    ProteinModelPortaliP28342.
    SMRiP28342. Positions 8-205.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini7 – 8882GST N-terminalAdd
    BLAST
    Domaini93 – 221129GST C-terminalAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni17 – 226Glutathione bindingBy similarity
    Regioni72 – 732Glutathione bindingBy similarity
    Regioni116 – 1183Glutathione bindingBy similarity

    Sequence similaritiesi

    Belongs to the GST superfamily. Zeta family.Curated
    Contains 1 GST C-terminal domain.Curated
    Contains 1 GST N-terminal domain.Curated

    Family and domain databases

    Gene3Di1.20.1050.10. 1 hit.
    3.40.30.10. 1 hit.
    InterProiIPR010987. Glutathione-S-Trfase_C-like.
    IPR004045. Glutathione_S-Trfase_N.
    IPR004046. GST_C.
    IPR005955. Mal_ac_isom.
    IPR012336. Thioredoxin-like_fold.
    [Graphical view]
    PfamiPF00043. GST_C. 1 hit.
    PF02798. GST_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF47616. SSF47616. 1 hit.
    SSF52833. SSF52833. 1 hit.
    TIGRFAMsiTIGR01262. maiA. 1 hit.
    PROSITEiPS50405. GST_CTER. 1 hit.
    PS50404. GST_NTER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P28342-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSSSETQKMQ LYSFSLSSCA WRVRIALHLK GLDFEYKAVD LFKGEHLTPE    50
    FLKLNPLGYV PVLVHGDIVI ADSLAIIMYL EEKFPENPLL PQDLQKRALN 100
    YQAANIVTSN IQPLQNLAVL NYIEEKLGSD EKLSWAKHHI KKGFSALEKL 150
    LKGHAGKYAT GDEVGLADLF LAPQIIASIT GFGMDMAEFP LLKSLNDAYL 200
    KYQHFRMRCQ RISPMLDEAK S 221
    Length:221
    Mass (Da):24,930
    Last modified:December 1, 1992 - v1
    Checksum:i13D03D0D4C8B3072
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti187 – 1871Missing in AAA72320. (PubMed:8499618)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M64268 mRNA. Translation: AAA33277.1.
    X58390 mRNA. Translation: CAA41279.1.
    L05915 Genomic DNA. Translation: AAA72320.1.
    PIRiS16604.
    S33628.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M64268 mRNA. Translation: AAA33277.1 .
    X58390 mRNA. Translation: CAA41279.1 .
    L05915 Genomic DNA. Translation: AAA72320.1 .
    PIRi S16604.
    S33628.

    3D structure databases

    ProteinModelPortali P28342.
    SMRi P28342. Positions 8-205.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 1.20.1050.10. 1 hit.
    3.40.30.10. 1 hit.
    InterProi IPR010987. Glutathione-S-Trfase_C-like.
    IPR004045. Glutathione_S-Trfase_N.
    IPR004046. GST_C.
    IPR005955. Mal_ac_isom.
    IPR012336. Thioredoxin-like_fold.
    [Graphical view ]
    Pfami PF00043. GST_C. 1 hit.
    PF02798. GST_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47616. SSF47616. 1 hit.
    SSF52833. SSF52833. 1 hit.
    TIGRFAMsi TIGR01262. maiA. 1 hit.
    PROSITEi PS50405. GST_CTER. 1 hit.
    PS50404. GST_NTER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "An ethylene-responsive flower senescence-related gene from carnation encodes a protein homologous to glutathione S-transferases."
      Meyer R.C. Jr., Goldsbrough P.B., Woodson W.R.
      Plant Mol. Biol. 17:277-281(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. White Sim.
      Tissue: Petal.
    2. "Characterization of an ethylene-responsive glutathione S-transferase gene cluster in carnation."
      Itzhaki H., Woodson W.R.
      Plant Mol. Biol. 22:43-58(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: cv. White Sim.
      Tissue: Petal.

    Entry informationi

    Entry nameiGSTZ1_DIACA
    AccessioniPrimary (citable) accession number: P28342
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 1992
    Last sequence update: December 1, 1992
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3