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P28342 (GSTZ1_DIACA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutathione S-transferase 1
EC=2.5.1.18
Alternative name(s):
GST class-zeta
SR8
Gene names
Name:GST1
Synonyms:CARSR8
OrganismDianthus caryophyllus (Carnation) (Clove pink)
Taxonomic identifier3570 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › Caryophyllales › Caryophyllaceae › Dianthus

Protein attributes

Sequence length221 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Catalytic activity

RX + glutathione = HX + R-S-glutathione.

Developmental stage

Senescing flowers.

Induction

Accumulates in response to the phytohormone ethylene.

Sequence similarities

Belongs to the GST superfamily. Zeta family.

Contains 1 GST C-terminal domain.

Contains 1 GST N-terminal domain.

Ontologies

Keywords
   Molecular functionTransferase
Gene Ontology (GO)
   Biological_processaromatic amino acid family metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutathione transferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 221221Glutathione S-transferase 1
PRO_0000186031

Regions

Domain7 – 8882GST N-terminal
Domain93 – 221129GST C-terminal
Region17 – 226Glutathione binding By similarity
Region72 – 732Glutathione binding By similarity
Region116 – 1183Glutathione binding By similarity

Sites

Binding site601Glutathione; via amide nitrogen and carbonyl oxygen By similarity
Binding site1121Glutathione By similarity

Experimental info

Sequence conflict1871Missing in AAA72320. Ref.2

Sequences

Sequence LengthMass (Da)Tools
P28342 [UniParc].

Last modified December 1, 1992. Version 1.
Checksum: 13D03D0D4C8B3072

FASTA22124,930
        10         20         30         40         50         60 
MSSSETQKMQ LYSFSLSSCA WRVRIALHLK GLDFEYKAVD LFKGEHLTPE FLKLNPLGYV 

        70         80         90        100        110        120 
PVLVHGDIVI ADSLAIIMYL EEKFPENPLL PQDLQKRALN YQAANIVTSN IQPLQNLAVL 

       130        140        150        160        170        180 
NYIEEKLGSD EKLSWAKHHI KKGFSALEKL LKGHAGKYAT GDEVGLADLF LAPQIIASIT 

       190        200        210        220 
GFGMDMAEFP LLKSLNDAYL KYQHFRMRCQ RISPMLDEAK S

« Hide

References

[1]"An ethylene-responsive flower senescence-related gene from carnation encodes a protein homologous to glutathione S-transferases."
Meyer R.C. Jr., Goldsbrough P.B., Woodson W.R.
Plant Mol. Biol. 17:277-281(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. White Sim.
Tissue: Petal.
[2]"Characterization of an ethylene-responsive glutathione S-transferase gene cluster in carnation."
Itzhaki H., Woodson W.R.
Plant Mol. Biol. 22:43-58(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: cv. White Sim.
Tissue: Petal.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		M64268 mRNA. Translation: AAA33277.1.
X58390 mRNA. Translation: CAA41279.1.
L05915 Genomic DNA. Translation: AAA72320.1.
PIRS16604.
S33628.

3D structure databases

ProteinModelPortalP28342.
SMRP28342. Positions 8-205.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR017933. Glutathione_S_Trfase/Cl_chnl_C.
IPR004046. GST_C.
IPR005955. Mal_ac_isom.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMSSF47616. GST_C_like. 1 hit.
SSF52833. Thiordxn-like_fd. 1 hit.
TIGRFAMsTIGR01262. maiA. 1 hit.
PROSITEPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSTZ1_DIACA
AccessionPrimary (citable) accession number: P28342
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 1, 1992
Last modified: April 3, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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