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Protein

DNA-damage-inducible protein F

Gene

dinF

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:DINF-MONOMER.
ECOL316407:JW4004-MONOMER.

Protein family/group databases

TCDBi2.A.66.1.4. the multidrug/oligosaccharidyl-lipid/polysaccharide (mop) flippase superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-damage-inducible protein F
Gene namesi
Name:dinF
Ordered Locus Names:b4044, JW4004
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11491. dinF.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei2 – 22HelicalSequence analysisAdd BLAST21
Transmembranei29 – 49HelicalSequence analysisAdd BLAST21
Transmembranei63 – 83HelicalSequence analysisAdd BLAST21
Transmembranei111 – 131HelicalSequence analysisAdd BLAST21
Transmembranei154 – 174HelicalSequence analysisAdd BLAST21
Transmembranei180 – 200HelicalSequence analysisAdd BLAST21
Transmembranei207 – 227HelicalSequence analysisAdd BLAST21
Transmembranei265 – 285HelicalSequence analysisAdd BLAST21
Transmembranei289 – 309HelicalSequence analysisAdd BLAST21
Transmembranei338 – 358HelicalSequence analysisAdd BLAST21
Transmembranei373 – 393HelicalSequence analysisAdd BLAST21
Transmembranei416 – 436HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001642581 – 459DNA-damage-inducible protein FAdd BLAST459

Proteomic databases

PaxDbiP28303.
PRIDEiP28303.

Expressioni

Inductioni

By DNA damage.

Interactioni

Protein-protein interaction databases

BioGridi4261722. 58 interactors.
STRINGi511145.b4044.

Structurei

3D structure databases

ProteinModelPortaliP28303.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107R73. Bacteria.
COG0534. LUCA.
HOGENOMiHOG000253154.
InParanoidiP28303.
KOiK03327.
OMAiQMVLGRD.
PhylomeDBiP28303.

Family and domain databases

InterProiIPR002528. MATE_fam.
[Graphical view]
PfamiPF01554. MatE. 2 hits.
[Graphical view]
TIGRFAMsiTIGR00797. matE. 1 hit.

Sequencei

Sequence statusi: Complete.

P28303-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPGVAVCFS SLFIRLVCMA FLTSSDKALW HLALPMIFSN ITVPLLGLVD
60 70 80 90 100
TAVIGHLDSP VYLGGVAVGA TATSFLFMLL LFLRMSTTGL TAQAYGAKNP
110 120 130 140 150
QALARTLVQP LLLALGAGAL IALLRTPIID LALHIVGGSE AVLEQARRFL
160 170 180 190 200
EIRWLSAPAS LANLVLLGWL LGVQYARAPV ILLVVGNILN IVLDVWLVMG
210 220 230 240 250
LHMNVQGAAL ATVIAEYATL LIGLLMVRKI LKLRGISGEM LKTAWRGNFR
260 270 280 290 300
RLLALNRDIM LRSLLLQLCF GAITVLGARL GSDIIAVNAV LMTLLTFTAY
310 320 330 340 350
ALDGFAYAVE AHSGQAYGAR DGSQLLDVWR AACRQSGIVA LLFSVVYLLA
360 370 380 390 400
GEHIIALLTS LTQIQQLADR YLIWQVILPV VGVWCYLLDG MFIGATRATE
410 420 430 440 450
MRNSMAVAAA GFALTLLTLP WLGNHALWLA LTVFLALRGL SLAAIWRRHW

RNGTWFAAT
Length:459
Mass (Da):49,646
Last modified:December 1, 1992 - v1
Checksum:i8F35355FE350079C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L02362 Genomic DNA. Translation: AAA24069.1.
U00006 Genomic DNA. Translation: AAC43138.1.
U00096 Genomic DNA. Translation: AAC77014.1.
AP009048 Genomic DNA. Translation: BAE78046.1.
PIRiC65212.
RefSeqiNP_418468.3. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAC77014; AAC77014; b4044.
BAE78046; BAE78046; BAE78046.
GeneIDi948554.
KEGGiecj:JW4004.
eco:b4044.
PATRICi32123625. VBIEscCol129921_4161.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L02362 Genomic DNA. Translation: AAA24069.1.
U00006 Genomic DNA. Translation: AAC43138.1.
U00096 Genomic DNA. Translation: AAC77014.1.
AP009048 Genomic DNA. Translation: BAE78046.1.
PIRiC65212.
RefSeqiNP_418468.3. NC_000913.3.

3D structure databases

ProteinModelPortaliP28303.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261722. 58 interactors.
STRINGi511145.b4044.

Protein family/group databases

TCDBi2.A.66.1.4. the multidrug/oligosaccharidyl-lipid/polysaccharide (mop) flippase superfamily.

Proteomic databases

PaxDbiP28303.
PRIDEiP28303.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC77014; AAC77014; b4044.
BAE78046; BAE78046; BAE78046.
GeneIDi948554.
KEGGiecj:JW4004.
eco:b4044.
PATRICi32123625. VBIEscCol129921_4161.

Organism-specific databases

EchoBASEiEB1454.
EcoGeneiEG11491. dinF.

Phylogenomic databases

eggNOGiENOG4107R73. Bacteria.
COG0534. LUCA.
HOGENOMiHOG000253154.
InParanoidiP28303.
KOiK03327.
OMAiQMVLGRD.
PhylomeDBiP28303.

Enzyme and pathway databases

BioCyciEcoCyc:DINF-MONOMER.
ECOL316407:JW4004-MONOMER.

Miscellaneous databases

PROiP28303.

Family and domain databases

InterProiIPR002528. MATE_fam.
[Graphical view]
PfamiPF01554. MatE. 2 hits.
[Graphical view]
TIGRFAMsiTIGR00797. matE. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiDINF_ECOLI
AccessioniPrimary (citable) accession number: P28303
Secondary accession number(s): Q2M6R0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 1, 1992
Last modified: November 2, 2016
This is version 130 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.