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P28303 (DINF_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 106. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
DNA-damage-inducible protein F
Gene names
Name:dinF
Ordered Locus Names:b4044, JW4004
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length459 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Cell inner membrane; Multi-pass membrane protein Ref.5.

Induction

By DNA damage.

Sequence similarities

Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. [View classification]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 459459DNA-damage-inducible protein F
PRO_0000164258

Regions

Transmembrane2 – 2221Helical; Potential
Transmembrane29 – 4921Helical; Potential
Transmembrane63 – 8321Helical; Potential
Transmembrane111 – 13121Helical; Potential
Transmembrane154 – 17421Helical; Potential
Transmembrane180 – 20021Helical; Potential
Transmembrane207 – 22721Helical; Potential
Transmembrane265 – 28521Helical; Potential
Transmembrane289 – 30921Helical; Potential
Transmembrane338 – 35821Helical; Potential
Transmembrane373 – 39321Helical; Potential
Transmembrane416 – 43621Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P28303 [UniParc].

Last modified December 1, 1992. Version 1.
Checksum: 8F35355FE350079C

FASTA45949,646
        10         20         30         40         50         60 
MPPGVAVCFS SLFIRLVCMA FLTSSDKALW HLALPMIFSN ITVPLLGLVD TAVIGHLDSP 

        70         80         90        100        110        120 
VYLGGVAVGA TATSFLFMLL LFLRMSTTGL TAQAYGAKNP QALARTLVQP LLLALGAGAL 

       130        140        150        160        170        180 
IALLRTPIID LALHIVGGSE AVLEQARRFL EIRWLSAPAS LANLVLLGWL LGVQYARAPV 

       190        200        210        220        230        240 
ILLVVGNILN IVLDVWLVMG LHMNVQGAAL ATVIAEYATL LIGLLMVRKI LKLRGISGEM 

       250        260        270        280        290        300 
LKTAWRGNFR RLLALNRDIM LRSLLLQLCF GAITVLGARL GSDIIAVNAV LMTLLTFTAY 

       310        320        330        340        350        360 
ALDGFAYAVE AHSGQAYGAR DGSQLLDVWR AACRQSGIVA LLFSVVYLLA GEHIIALLTS 

       370        380        390        400        410        420 
LTQIQQLADR YLIWQVILPV VGVWCYLLDG MFIGATRATE MRNSMAVAAA GFALTLLTLP 

       430        440        450 
WLGNHALWLA LTVFLALRGL SLAAIWRRHW RNGTWFAAT

« Hide

References

« Hide 'large scale' references
[1]"E. coli dinF gene."
Lilley P.E., Dixon N.E.
Submitted (SEP-1992) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: K12.
[2]"Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes."
Blattner F.R., Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L.
Nucleic Acids Res. 21:5408-5417(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[3]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[4]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[5]"Global topology analysis of the Escherichia coli inner membrane proteome."
Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION.
Strain: K12 / MG1655 / ATCC 47076.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L02362 Genomic DNA. Translation: AAA24069.1.
U00006 Genomic DNA. Translation: AAC43138.1.
U00096 Genomic DNA. Translation: AAC77014.1.
AP009048 Genomic DNA. Translation: BAE78046.1.
PIRC65212.
RefSeqNP_418468.3. NC_000913.2.
YP_492187.1. NC_007779.1.

3D structure databases

ProteinModelPortalP28303.
ModBaseSearch...

Protein-protein interaction databases

STRING511145.b4044.

Protein family/group databases

TCDB2.A.66.1.4. multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) flippase superfamily.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC77014; AAC77014; b4044.
BAE78046; BAE78046; BAE78046.
GeneID12932728.
948554.
KEGGecj:Y75_p3931.
eco:b4044.
PATRIC32123625. VBIEscCol129921_4161.

Organism-specific databases

EchoBASEEB1454.
EcoGeneEG11491. dinF.

Phylogenomic databases

eggNOGCOG0534.
HOGENOMHOG000253154.
KOK03327.
OMAGAEMRNS.
ProtClustDBPRK10367.

Enzyme and pathway databases

BioCycEcoCyc:DINF-MONOMER.
ECOL316407:JW4004-MONOMER.

Gene expression databases

GenevestigatorP28303.

Family and domain databases

InterProIPR002528. MATE.
[Graphical view]
PfamPF01554. MatE. 2 hits.
[Graphical view]
TIGRFAMsTIGR00797. matE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDINF_ECOLI
AccessionPrimary (citable) accession number: P28303
Secondary accession number(s): Q2M6R0
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 1, 1992
Last modified: May 1, 2013
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene

SIMILARITY comments

Index of protein domains and families

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