Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P28270

- DHE3_ELEEL

UniProt

P28270 - DHE3_ELEEL

Protein

Glutamate dehydrogenase

Gene
N/A
Organism
Electrophorus electricus (Electric eel) (Gymnotus electricus)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Mitochondrial glutamate dehydrogenase that converts L-glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle By similarity.By similarity

    Catalytic activityi

    L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H.PROSITE-ProRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei31 – 311SubstrateBy similarity

    GO - Molecular functioni

    1. glutamate dehydrogenase [NAD(P)+] activity Source: UniProtKB

    GO - Biological processi

    1. glutamine metabolic process Source: UniProtKB
    2. tricarboxylic acid metabolic process Source: UniProtKB

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NADP

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate dehydrogenase (EC:1.4.1.3)
    Short name:
    GDH
    OrganismiElectrophorus electricus (Electric eel) (Gymnotus electricus)
    Taxonomic identifieri8005 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiGymnotiformesGymnotoideiGymnotidaeElectrophorus

    Subcellular locationi

    Mitochondrion matrix By similarity

    GO - Cellular componenti

    1. mitochondrial matrix Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Mitochondrion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – ›51›51Glutamate dehydrogenasePRO_0000182744Add
    BLAST

    Interactioni

    Subunit structurei

    Homohexamer.

    Structurei

    3D structure databases

    ProteinModelPortaliP28270.
    SMRiP28270. Positions 5-47.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Sequencei

    Sequence statusi: Fragments.

    P28270-1 [UniParc]FASTAAdd to Basket

    « Hide

    SEAVAEKEDD PNFFKMVEGF FDKGAAIVEN KLVEDLKTRG SPEVEGNLTF   50
    T 51
    Length:51
    Mass (Da):5,650
    Last modified:December 1, 1992 - v1
    Checksum:i499A36DF9A05B004
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-adjacent residuesi43 – 442Curated
    Non-terminal residuei51 – 511

    Cross-referencesi

    3D structure databases

    ProteinModelPortali P28270.
    SMRi P28270. Positions 5-47.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "The trypsin-catalyzed activation of glutamate dehydrogenase purified from eel liver."
      Tang M.-Q., Ando S., Yamada S., Hayashi S.
      J. Biochem. 111:655-661(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE.
      Tissue: Liver.

    Entry informationi

    Entry nameiDHE3_ELEEL
    AccessioniPrimary (citable) accession number: P28270
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 1992
    Last sequence update: December 1, 1992
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3