Cell division protein FtsA - Bacillus subtilis (strain 168)

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P28264 (FTSA_BACSU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 88. History...

Clusters with 100%, 90%, 50% identity |

Documents (2) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Cell division protein FtsA

Gene names

Name:	ftsA
Ordered Locus Names:	BSU15280

Organism

Bacillus subtilis (strain 168) [Reference proteome] [HAMAP]

Taxonomic identifier

224308 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus ›

Protein attributes

Sequence length	440 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	This protein may be involved in anomalous filament growth. May be a component of the septum By similarity.
Subunit structure	Interacts with FtsZ By similarity.
Sequence similarities	Belongs to the FtsA/MreB family.

Ontologies

Keywords
Biological process	Cell cycle Cell division Cell shape
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell cycle Inferred from electronic annotation. Source: UniProtKB-KW cell division Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
ezrA	O34894	5	EBI-2122615,EBI-1567579
ftsZ	P17865	7	EBI-2122615,EBI-1569853

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 440

440

Cell division protein FtsA

PRO_0000062729

Experimental info

Sequence conflict

I → L in AAA22456. Ref.1

Sequence conflict

D → G in AAA22456. Ref.1

Sequence conflict

112

E → A in AAA22456. Ref.1

Sequence conflict

349 – 350

AS → QG in AAA22456. Ref.1

Sequences

Sequence

Length

Mass (Da)

Tools

P28264 [UniParc].

Last modified June 16, 2009. Version 2.
Checksum: 4BF656A8C71BF15A
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FASTA

440

48,192

        10         20         30         40         50         60 
MNNNELYVSL DIGTSNTKVI VGEMTDDSLN IIGVGNVPSE GLKKGSIVDI DETVHSIRKA 

        70         80         90        100        110        120 
FDQAERMVGF PLRKAIVGVN GNYINIQDTN GVVAVSSENK EIQVEDVRRV MEAAQVVSVP 

       130        140        150        160        170        180 
HEQLIVDVIP KQFIVDGRDE ITDPKKMLGV RLEVEGTLIT GSKTILHNLL RCVERAGIEI 

       190        200        210        220        230        240 
TDICLQPLAA GSAALSKDEK NLGVALIDIG GGSTTIAVFQ NGHLTSTRVI PLGGENITKD 

       250        260        270        280        290        300 
ISIGLRTSTE EAERVKKQLG HAYYDEASED EIFEVTVIGT NQKQTFTQQE AANIIEARVE 

       310        320        330        340        350        360 
EILEIVSEEL RSMGITDLPG GFVLTGGQAA MPGVMSLAQD VLQNNVRVAS PNYIGVRDPQ 

       370        380        390        400        410        420 
YMTGVGLIQF ACRNARIQGR KIGFKMPEEA IQEIAVSSSE EQEQHHHQNE VQQRPKGKQK 

       430        440 
TQAEHNKQSK MKKLLSMFWE

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning and characterization of Bacillus subtilis homologs of Escherichia coli cell division genes ftsZ and ftsA." Beall B., Lowe M., Lutkenhaus J. J. Bacteriol. 170:4855-4864(1988) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. Danchin A. Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168.
[3]	"From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later." Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A., Vallenet D., Wang T., Moszer I., Medigue C., Danchin A. Microbiology 155:1758-1775(2009) [PubMed] [Europe PMC] [Abstract] Cited for: SEQUENCE REVISION TO 12; 26; 112 AND 349-350.
[4]	"Developmental regulation of transcription of the Bacillus subtilis ftsAZ operon." Gonzy-Treboul G., Karmazyn-Campelli C., Stragier P. J. Mol. Biol. 224:967-979(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-14. Strain: 168 / JH642.
[5]	"Regulation of transcription of the cell division gene ftsA during sporulation of Bacillus subtilis." Gholamhoseinian A., Shen Z., Wu J.J., Piggot P. J. Bacteriol. 174:4647-4656(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-8.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M22630 Genomic DNA. Translation: AAA22456.1. AL009126 Genomic DNA. Translation: CAB13401.2. X66239 Genomic DNA. Translation: CAA46968.1. S39431 Genomic DNA. Translation: AAD13818.1.
PIR	I39847.
RefSeq	NP_389411.2. NC_000964.3.
3D structure databases
ProteinModelPortal	P28264.
SMR	P28264. Positions 3-371.
ModBase	Search...
Protein-protein interaction databases
IntAct	P28264. 25 interactions.
STRING	224308.BSU15280.
Proteomic databases
PaxDb	P28264.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAB13401; CAB13401; BSU15280.
GeneID	936145.
KEGG	bsu:BSU15280.
PATRIC	18974861. VBIBacSub10457_1622.
Organism-specific databases
GenoList	BSU15280. [Micado]
Phylogenomic databases
eggNOG	COG0849.
HOGENOM	HOG000049205.
KO	K03590.
ProtClustDB	CLSK2460919.
Enzyme and pathway databases
BioCyc	BSUB:BSU15280-MONOMER.
Family and domain databases
InterPro	IPR020823. Cell_div_FtsA. IPR003494. SHS2_FtsA. [Graphical view]
Pfam	PF02491. SHS2_FTSA. 1 hit. [Graphical view]
PIRSF	PIRSF003101. FtsA. 1 hit.
SMART	SM00842. FtsA. 1 hit. [Graphical view]
TIGRFAMs	TIGR01174. ftsA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FTSA_BACSU

Accession

Primary (citable) accession number: P28264
Secondary accession number(s): Q45573

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 1992
Last sequence update:	June 16, 2009
Last modified:	May 1, 2013
This is version 88 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

Bacillus subtilis

Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Binary interactions

With

Entry

#Exp.

IntAct

Notes

Sequence annotation (Features)

Molecule processing

Experimental info

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry information

Relevant documents