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Protein

Protein AsmA

Gene

asmA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in the inhibition of assembly of mutant ompF proteins. In general, could be involved in the assembly of outer membrane proteins.

GO - Biological processi

  • regulation of protein targeting to membrane Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG11361-MONOMER.
ECOL316407:JW2049-MONOMER.

Protein family/group databases

TCDBi9.B.22.2.1. the leukotoxin secretion morphogenesis protein c (morc) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein AsmA
Gene namesi
Name:asmA
Synonyms:yegA
Ordered Locus Names:b2064, JW2049
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11361. asmA.

Subcellular locationi

GO - Cellular componenti

  • periplasmic space Source: UniProtKB-SubCell
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence analysisAdd
BLAST
Chaini23 – 617595Protein AsmAPRO_0000020759Add
BLAST

Proteomic databases

PaxDbiP28249.

Interactioni

Protein-protein interaction databases

BioGridi4259685. 258 interactions.
DIPiDIP-9175N.
IntActiP28249. 9 interactions.
STRINGi511145.b2064.

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4108GAE. Bacteria.
COG2982. LUCA.
HOGENOMiHOG000121998.
InParanoidiP28249.
KOiK07289.
OMAiDIRLQME.

Family and domain databases

InterProiIPR007844. AsmA.
[Graphical view]
PfamiPF05170. AsmA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P28249-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRFLTTLMI LLVVLVAGLS ALVLLVNPND FRDYMVKQVA ARSGYQLQLD
60 70 80 90 100
GPLRWHVWPQ LSILSGRMSL TAQGASQPLV RADNMRLDVA LLPLLSHQLS
110 120 130 140 150
VKQVMLKGAV IQLTPQTEAV RSEDAPVAPR DNTLPDLSDD RGWSFDISSL
160 170 180 190 200
KVADSVLVFQ HEDDEQVTIR NIRLQMEQDP QHRGSFEFSG RVNRDQRDLT
210 220 230 240 250
ISLNGTVDAS DYPHDLTAAI EQINWQLQGA DLPKQGIQGQ GSFQAQWQES
260 270 280 290 300
HKRLSFNQIS LTANDSTLSG QAQVTLTEKP EWQLRLQFPQ LNLDNLIPLN
310 320 330 340 350
ETANGENGAA QQGQSQSTLP RPVISSRIDE PAYQGLQGFT ADILLQASNV
360 370 380 390 400
RWRGMNFTDV ATQMTNKSGL LEITQLQGKL NGGQVSLPGT LDATSINPRI
410 420 430 440 450
NFQPRLENVE IGTILKAFNY PISLTGKMSL AGDFSGADID ADAFRHNWQG
460 470 480 490 500
QAHVEMTDTR MEGMNFQQMI QQAVERNGGD VKAAENFDNV TRLDRFTTDL
510 520 530 540 550
TLKDGVVTLN DMQGQSPVLA LTGEGMLNLA DQTCDTQFDI RVVGGWNGES
560 570 580 590 600
KLIDFLKETP VPLRVYGNWQ QLNYSLQVDQ LLRKHLQDEA KRRLNDWAER
610
NKDSRNGKDV KKLLEKM
Length:617
Mass (Da):68,963
Last modified:November 1, 1997 - v2
Checksum:i23AD060D864BC680
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti354 – 37926GMNFT…QLQGK → NEFYRCCHANDQQVGFAGNY STAGQT (PubMed:7476172).CuratedAdd
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U11035 Genomic DNA. Translation: AAD14778.1.
U00096 Genomic DNA. Translation: AAC75125.1.
AP009048 Genomic DNA. Translation: BAA15917.1.
M90069 Genomic DNA. Translation: AAA23670.1.
PIRiG64972.
RefSeqiNP_416568.1. NC_000913.3.
WP_001252331.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75125; AAC75125; b2064.
BAA15917; BAA15917; BAA15917.
GeneIDi946582.
KEGGiecj:JW2049.
eco:b2064.
PATRICi32119461. VBIEscCol129921_2141.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U11035 Genomic DNA. Translation: AAD14778.1.
U00096 Genomic DNA. Translation: AAC75125.1.
AP009048 Genomic DNA. Translation: BAA15917.1.
M90069 Genomic DNA. Translation: AAA23670.1.
PIRiG64972.
RefSeqiNP_416568.1. NC_000913.3.
WP_001252331.1. NZ_LN832404.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259685. 258 interactions.
DIPiDIP-9175N.
IntActiP28249. 9 interactions.
STRINGi511145.b2064.

Protein family/group databases

TCDBi9.B.22.2.1. the leukotoxin secretion morphogenesis protein c (morc) family.

Proteomic databases

PaxDbiP28249.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75125; AAC75125; b2064.
BAA15917; BAA15917; BAA15917.
GeneIDi946582.
KEGGiecj:JW2049.
eco:b2064.
PATRICi32119461. VBIEscCol129921_2141.

Organism-specific databases

EchoBASEiEB1336.
EcoGeneiEG11361. asmA.

Phylogenomic databases

eggNOGiENOG4108GAE. Bacteria.
COG2982. LUCA.
HOGENOMiHOG000121998.
InParanoidiP28249.
KOiK07289.
OMAiDIRLQME.

Enzyme and pathway databases

BioCyciEcoCyc:EG11361-MONOMER.
ECOL316407:JW2049-MONOMER.

Miscellaneous databases

PROiP28249.

Family and domain databases

InterProiIPR007844. AsmA.
[Graphical view]
PfamiPF05170. AsmA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiASMA_ECOLI
AccessioniPrimary (citable) accession number: P28249
Secondary accession number(s): P76390
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: November 1, 1997
Last modified: September 7, 2016
This is version 101 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.