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Protein

Tyrosine-protein phosphatase 14

Gene

STY-14

Organism
Styela plicata (Wrinkled sea squirt) (Ascidia plicata)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei84SubstrateBy similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Tyrosine-protein phosphatase 14 (EC:3.1.3.48)
Gene namesi
Name:STY-14
OrganismiStyela plicata (Wrinkled sea squirt) (Ascidia plicata)
Taxonomic identifieri7726 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataTunicataAscidiaceaStolidobranchiaStyelidaeStyela

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000094902‹1 – ›116Tyrosine-protein phosphatase 14Add BLAST›116

Structurei

3D structure databases

ProteinModelPortaliP28206.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini‹1 – ›116Tyrosine-protein phosphatasePROSITE-ProRule annotationAdd BLAST›116

Sequence similaritiesi

Contains 1 tyrosine-protein phosphatase domain.PROSITE-ProRule annotation

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR000242. PTPase_domain.
[Graphical view]
PfamiPF00102. Y_phosphatase. 1 hit.
[Graphical view]
SMARTiSM00194. PTPc. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

P28206-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
WRMITQEKAQ VIVMTTKEVE RGRNKCIRYW PPEGESKEYG AYTLLNAKEN
60 70 80 90 100
DFRDYTWRQF VITKESDPPY KQIIYHHHFK VWPDHGVPSD PGGVLNFLHE
110
INECQRSLKN PGPVIV
Length:116
Mass (Da):13,729
Last modified:December 1, 1992 - v1
Checksum:i4FE499C5432E3505
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11
Non-terminal residuei1161

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M37999 mRNA. Translation: AAA29832.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M37999 mRNA. Translation: AAA29832.1.

3D structure databases

ProteinModelPortaliP28206.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR000242. PTPase_domain.
[Graphical view]
PfamiPF00102. Y_phosphatase. 1 hit.
[Graphical view]
SMARTiSM00194. PTPc. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPTP14_STYPL
AccessioniPrimary (citable) accession number: P28206
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 1, 1992
Last modified: May 11, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.