Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P28204

- PTP12_STYPL

UniProt

P28204 - PTP12_STYPL

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Tyrosine-protein phosphatase 12

Gene

STY-12

Organism
Styela plicata (Wrinkled sea squirt) (Ascidia plicata)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei84 – 841SubstrateBy similarity

GO - Molecular functioni

  1. protein tyrosine phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Tyrosine-protein phosphatase 12 (EC:3.1.3.48)
Gene namesi
Name:STY-12
OrganismiStyela plicata (Wrinkled sea squirt) (Ascidia plicata)
Taxonomic identifieri7726 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataTunicataAscidiaceaStolidobranchiaStyelidaeStyela

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – ›105›105Tyrosine-protein phosphatase 12PRO_0000094900Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP28204.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini‹1 – ›105›105Tyrosine-protein phosphatasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 tyrosine-protein phosphatase domain.PROSITE-ProRule annotation

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR000242. Tyr_Pase_rcpt/non-rcpt.
[Graphical view]
PfamiPF00102. Y_phosphatase. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

P28204-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
WRMIWEKRVE AIVMLTNVDE NGRRKCEKYW PGDTERGSHG EFEVSCIDNT
60 70 80 90 100
TLGQIIRRKF KISHQSYPNR TQVVVQYHYT AWPDHGVPQT TSELFNLRRI

VRTEF
Length:105
Mass (Da):12,569
Last modified:December 1, 1992 - v1
Checksum:i44B85DCA28BC2371
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11
Non-terminal residuei105 – 1051

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M37997 mRNA. Translation: AAA29830.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M37997 mRNA. Translation: AAA29830.1 .

3D structure databases

ProteinModelPortali P28204.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.90.190.10. 1 hit.
InterProi IPR029021. Prot-tyrosine_phosphatase-like.
IPR000242. Tyr_Pase_rcpt/non-rcpt.
[Graphical view ]
Pfami PF00102. Y_phosphatase. 1 hit.
[Graphical view ]
SUPFAMi SSF52799. SSF52799. 1 hit.
PROSITEi PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Protein tyrosine phosphatase domains from the protochordate Styela plicata."
    Matthews R.J., Flores E., Thomas M.L.
    Immunogenetics 33:33-41(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiPTP12_STYPL
AccessioniPrimary (citable) accession number: P28204
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 1, 1992
Last modified: October 1, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3