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P28204 (PTP12_STYPL) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Tyrosine-protein phosphatase 12

EC=3.1.3.48
Gene names
Name:STY-12
OrganismStyela plicata (Wrinkled sea squirt) (Ascidia plicata)
Taxonomic identifier7726 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataTunicataAscidiaceaStolidobranchiaStyelidaeStyela

Protein attributes

Sequence length105 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sequence similarities

Belongs to the protein-tyrosine phosphatase family.

Contains 1 tyrosine-protein phosphatase domain.

Ontologies

Keywords
   Molecular functionHydrolase
Protein phosphatase
Gene Ontology (GO)
   Molecular_functionprotein tyrosine phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – ›105›105Tyrosine-protein phosphatase 12
PRO_0000094900

Regions

Domain‹1 – ›105›105Tyrosine-protein phosphatase

Sites

Binding site841Substrate By similarity

Experimental info

Non-terminal residue11
Non-terminal residue1051

Sequences

Sequence LengthMass (Da)Tools
P28204 [UniParc].

Last modified December 1, 1992. Version 1.
Checksum: 44B85DCA28BC2371

FASTA10512,569
        10         20         30         40         50         60 
WRMIWEKRVE AIVMLTNVDE NGRRKCEKYW PGDTERGSHG EFEVSCIDNT TLGQIIRRKF 

        70         80         90        100 
KISHQSYPNR TQVVVQYHYT AWPDHGVPQT TSELFNLRRI VRTEF 

« Hide

References

[1]"Protein tyrosine phosphatase domains from the protochordate Styela plicata."
Matthews R.J., Flores E., Thomas M.L.
Immunogenetics 33:33-41(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M37997 mRNA. Translation: AAA29830.1.

3D structure databases

ProteinModelPortalP28204.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR000242. Tyr_Pase_rcpt/non-rcpt.
[Graphical view]
PfamPF00102. Y_phosphatase. 1 hit.
[Graphical view]
PROSITEPS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePTP12_STYPL
AccessionPrimary (citable) accession number: P28204
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 1, 1992
Last modified: April 16, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families