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Protein

Tyrosine-protein phosphatase 12

Gene

STY-12

Organism
Styela plicata (Wrinkled sea squirt) (Ascidia plicata)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei84SubstrateBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Tyrosine-protein phosphatase 12 (EC:3.1.3.48)
Gene namesi
Name:STY-12
OrganismiStyela plicata (Wrinkled sea squirt) (Ascidia plicata)
Taxonomic identifieri7726 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataTunicataAscidiaceaStolidobranchiaStyelidaeStyela

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000094900‹1 – ›105Tyrosine-protein phosphatase 12Add BLAST›105

Structurei

3D structure databases

ProteinModelPortaliP28204.
SMRiP28204.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini‹1 – ›105Tyrosine-protein phosphatasePROSITE-ProRule annotationAdd BLAST›105

Sequence similaritiesi

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiView protein in InterPro
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000242. PTPase_domain.
IPR028855. R-PTP-H.
PANTHERiPTHR19134:SF297. PTHR19134:SF297. 1 hit.
PfamiView protein in Pfam
PF00102. Y_phosphatase. 1 hit.
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiView protein in PROSITE
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.

Sequencei

Sequence statusi: Fragment.

P28204-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
WRMIWEKRVE AIVMLTNVDE NGRRKCEKYW PGDTERGSHG EFEVSCIDNT
60 70 80 90 100
TLGQIIRRKF KISHQSYPNR TQVVVQYHYT AWPDHGVPQT TSELFNLRRI

VRTEF
Length:105
Mass (Da):12,569
Last modified:December 1, 1992 - v1
Checksum:i44B85DCA28BC2371
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11
Non-terminal residuei1051

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M37997 mRNA. Translation: AAA29830.1.

Entry informationi

Entry nameiPTP12_STYPL
AccessioniPrimary (citable) accession number: P28204
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 1, 1992
Last modified: October 25, 2017
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families