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P28198

- PTP6_STYPL

UniProt

P28198 - PTP6_STYPL

Protein

Tyrosine-protein phosphatase 6

Gene

STY-6

Organism
Styela plicata (Wrinkled sea squirt) (Ascidia plicata)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    Catalytic activityi

    Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.PROSITE-ProRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei76 – 761SubstrateBy similarity

    GO - Molecular functioni

    1. protein tyrosine phosphatase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Tyrosine-protein phosphatase 6 (EC:3.1.3.48)
    Gene namesi
    Name:STY-6
    OrganismiStyela plicata (Wrinkled sea squirt) (Ascidia plicata)
    Taxonomic identifieri7726 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataTunicataAscidiaceaStolidobranchiaStyelidaeStyela

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – ›109›109Tyrosine-protein phosphatase 6PRO_0000094894Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP28198.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini‹1 – ›109›109Tyrosine-protein phosphatasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 tyrosine-protein phosphatase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    HOVERGENiHBG096909.

    Family and domain databases

    Gene3Di3.90.190.10. 1 hit.
    InterProiIPR029021. Prot-tyrosine_phosphatase-like.
    IPR000242. Tyr_Pase_rcpt/non-rcpt.
    [Graphical view]
    PfamiPF00102. Y_phosphatase. 1 hit.
    [Graphical view]
    SUPFAMiSSF52799. SSF52799. 1 hit.
    PROSITEiPS50055. TYR_PHOSPHATASE_PTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    P28198-1 [UniParc]FASTAAdd to Basket

    « Hide

    YNINVIVMVC REIELGKKKC ERYWADRGDS KRFGDITVTL SKKEDLKDGY    50
    CLRTIKAEKG NEIRYIKQFH YTSWPDHGVP KTCLEILSLI NHVRDVQSYS 100
    EDETTPLCV 109
    Length:109
    Mass (Da):12,744
    Last modified:December 1, 1992 - v1
    Checksum:iBED2D6F524AE88EB
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11
    Non-terminal residuei109 – 1091

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M37991 mRNA. Translation: AAA29824.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M37991 mRNA. Translation: AAA29824.1 .

    3D structure databases

    ProteinModelPortali P28198.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG096909.

    Family and domain databases

    Gene3Di 3.90.190.10. 1 hit.
    InterProi IPR029021. Prot-tyrosine_phosphatase-like.
    IPR000242. Tyr_Pase_rcpt/non-rcpt.
    [Graphical view ]
    Pfami PF00102. Y_phosphatase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52799. SSF52799. 1 hit.
    PROSITEi PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Protein tyrosine phosphatase domains from the protochordate Styela plicata."
      Matthews R.J., Flores E., Thomas M.L.
      Immunogenetics 33:33-41(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiPTP6_STYPL
    AccessioniPrimary (citable) accession number: P28198
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 1992
    Last sequence update: December 1, 1992
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    STY 3 and STY 6 may represent a double domain transmembrane protein tyrosine phosphatase.

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3