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Protein

Ras-related protein RABE1c

Gene

RABE1C

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Involved in membrane trafficking from the Golgi to the plasma membrane.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi22 – 298GTPBy similarity
Nucleotide bindingi70 – 745GTPBy similarity
Nucleotide bindingi128 – 1314GTPBy similarity
Nucleotide bindingi159 – 1602GTPBy similarity

GO - Molecular functioni

  • GTP binding Source: TAIR

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-ATH-1445148. Translocation of GLUT4 to the plasma membrane.
R-ATH-5620916. VxPx cargo-targeting to cilium.

Names & Taxonomyi

Protein namesi
Recommended name:
Ras-related protein RABE1c
Short name:
AtRABE1c
Alternative name(s):
Ras-related protein Ara-3
Ras-related protein Rab8A
Short name:
AtRab8A
Gene namesi
Name:RABE1C
Synonyms:ARA-3, RAB8A
Ordered Locus Names:At3g46060
ORF Names:F12M12.30
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G46060.

Subcellular locationi

GO - Cellular componenti

  • Golgi membrane Source: UniProtKB-SubCell
  • plasma membrane Source: TAIR
  • vacuolar membrane Source: TAIR
  • vacuole Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 216216Ras-related protein RABE1cPRO_0000121289Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi213 – 2131S-geranylgeranyl cysteineBy similarity
Lipidationi214 – 2141S-geranylgeranyl cysteineBy similarity

Keywords - PTMi

Lipoprotein, Prenylation

Proteomic databases

PaxDbiP28186.
PRIDEiP28186.

PTM databases

iPTMnetiP28186.

Expressioni

Inductioni

By ethylene.1 Publication

Gene expression databases

GenevisibleiP28186. AT.

Interactioni

Subunit structurei

Interacts with PI5K2.1 Publication

Protein-protein interaction databases

BioGridi9069. 11 interactions.
IntActiP28186. 10 interactions.
STRINGi3702.AT3G46060.1.

Structurei

3D structure databases

ProteinModelPortaliP28186.
SMRiP28186. Positions 13-181.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi44 – 529Effector regionBy similarity

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rab family.Curated

Phylogenomic databases

eggNOGiKOG0078. Eukaryota.
ENOG410XPUI. LUCA.
HOGENOMiHOG000233968.
InParanoidiP28186.
KOiK07901.
OMAiIEEXLAL.
OrthoDBiEOG09360P8P.
PhylomeDBiP28186.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51419. RAB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P28186-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAPPARARA DYDYLIKLLL IGDSGVGKSC LLLRFSDGSF TTSFITTIGI
60 70 80 90 100
DFKIRTIELD GKRIKLQIWD TAGQERFRTI TTAYYRGAMG ILLVYDVTDE
110 120 130 140 150
SSFNNIRNWI RNIEQHASDN VNKILVGNKA DMDESKRAVP TAKGQALADE
160 170 180 190 200
YGIKFFETSA KTNLNVEEVF FSIGRDIKQR LSDTDSRAEP ATIKISQTDQ
210
AAGAGQATQK SACCGT
Length:216
Mass (Da):23,835
Last modified:December 1, 1992 - v1
Checksum:i09E9C19A7A44E705
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D01025 mRNA. Translation: BAA00830.1.
AL355775 Genomic DNA. Translation: CAB90933.1.
CP002686 Genomic DNA. Translation: AEE78106.1.
CP002686 Genomic DNA. Translation: AEE78107.1.
CP002686 Genomic DNA. Translation: AEE78108.1.
AY035132 mRNA. Translation: AAK59637.1.
AY042795 mRNA. Translation: AAK68735.1.
BT001952 mRNA. Translation: AAN71951.1.
BT002186 mRNA. Translation: AAN72197.1.
PIRiJS0640.
RefSeqiNP_001078248.1. NM_001084779.1.
NP_001118780.1. NM_001125308.1.
NP_190192.1. NM_114475.3.
UniGeneiAt.258.

Genome annotation databases

EnsemblPlantsiAT3G46060.1; AT3G46060.1; AT3G46060.
AT3G46060.2; AT3G46060.2; AT3G46060.
AT3G46060.3; AT3G46060.3; AT3G46060.
GeneIDi823749.
GrameneiAT3G46060.1; AT3G46060.1; AT3G46060.
AT3G46060.2; AT3G46060.2; AT3G46060.
AT3G46060.3; AT3G46060.3; AT3G46060.
KEGGiath:AT3G46060.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D01025 mRNA. Translation: BAA00830.1.
AL355775 Genomic DNA. Translation: CAB90933.1.
CP002686 Genomic DNA. Translation: AEE78106.1.
CP002686 Genomic DNA. Translation: AEE78107.1.
CP002686 Genomic DNA. Translation: AEE78108.1.
AY035132 mRNA. Translation: AAK59637.1.
AY042795 mRNA. Translation: AAK68735.1.
BT001952 mRNA. Translation: AAN71951.1.
BT002186 mRNA. Translation: AAN72197.1.
PIRiJS0640.
RefSeqiNP_001078248.1. NM_001084779.1.
NP_001118780.1. NM_001125308.1.
NP_190192.1. NM_114475.3.
UniGeneiAt.258.

3D structure databases

ProteinModelPortaliP28186.
SMRiP28186. Positions 13-181.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi9069. 11 interactions.
IntActiP28186. 10 interactions.
STRINGi3702.AT3G46060.1.

PTM databases

iPTMnetiP28186.

Proteomic databases

PaxDbiP28186.
PRIDEiP28186.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G46060.1; AT3G46060.1; AT3G46060.
AT3G46060.2; AT3G46060.2; AT3G46060.
AT3G46060.3; AT3G46060.3; AT3G46060.
GeneIDi823749.
GrameneiAT3G46060.1; AT3G46060.1; AT3G46060.
AT3G46060.2; AT3G46060.2; AT3G46060.
AT3G46060.3; AT3G46060.3; AT3G46060.
KEGGiath:AT3G46060.

Organism-specific databases

TAIRiAT3G46060.

Phylogenomic databases

eggNOGiKOG0078. Eukaryota.
ENOG410XPUI. LUCA.
HOGENOMiHOG000233968.
InParanoidiP28186.
KOiK07901.
OMAiIEEXLAL.
OrthoDBiEOG09360P8P.
PhylomeDBiP28186.

Enzyme and pathway databases

ReactomeiR-ATH-1445148. Translocation of GLUT4 to the plasma membrane.
R-ATH-5620916. VxPx cargo-targeting to cilium.

Miscellaneous databases

PROiP28186.

Gene expression databases

GenevisibleiP28186. AT.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51419. RAB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRAE1C_ARATH
AccessioniPrimary (citable) accession number: P28186
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 1, 1992
Last modified: September 7, 2016
This is version 136 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.