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P28006 (GAC1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 104. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein phosphatase 1 regulatory subunit GAC1
Gene names
Name:GAC1
Ordered Locus Names:YOR178C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length793 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Regulates the activity of glycogen synthase. It is most probably a regulatory subunit for protein phosphatase type 1.

Sequence similarities

Contains 1 CBM21 (carbohydrate binding type-21) domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 793793Serine/threonine-protein phosphatase 1 regulatory subunit GAC1
PRO_0000071518

Regions

Domain235 – 360126CBM21
Compositional bias500 – 52324Ser-rich

Amino acid modifications

Modified residue4151Phosphoserine Ref.4
Modified residue4241Phosphoserine Ref.4

Experimental info

Sequence conflict2281S → SS in CAA45371. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P28006 [UniParc].

Last modified November 1, 1997. Version 2.
Checksum: 1880E966A6480D80

FASTA79388,533
        10         20         30         40         50         60 
MVIQTATTLS PAKARPSFPH NDLIKSMSDS LISRPTHPPI RKLKSSLKIS HPEPISRSKS 

        70         80         90        100        110        120 
EIFCTSPEKN VRFAIELTTV KRFDKNAEPS SISNENSPTL SPVDSNTAAD DVQLFNNEDC 

       130        140        150        160        170        180 
WFNDSSLVTN LLKNEKKFRY MNSLNNMFKL DLYDSEDEDD IDEHINSQAE YGYTYNSLST 

       190        200        210        220        230        240 
RGKTSENKSA TSSLATQATN ICDWKLHCTD LVPFKIAPPL FTKTLSASDL QGQLTKYLNG 

       250        260        270        280        290        300 
QNVKLHSLTQ LGDDSSKITG LVYVKNLSFE KYLEIKFTFN SWRDIHYVTA NFNRTINSNV 

       310        320        330        340        350        360 
DEFKFTIDLN SLKYILLIKR IITMEKNTSS CPLNIELCCR YDVNNETYYD NNNGKNYHLF 

       370        380        390        400        410        420 
MTTFKKGGET KEKIPVVVEP ASQTDAAMSP KEMKARFVSS NPTLSRFLPQ SRKFSEDTDY 

       430        440        450        460        470        480 
YNTSPLKHLY HNDTTSWVKP KRLNVVLDKL ENATPPPPSS ALANDTARTG KITKDKNNVL 

       490        500        510        520        530        540 
APPTASNSID LPILGSQHQS LYSGSSSYSS SSSSISSSLS FASSNNSSTN SSSASCSFPL 

       550        560        570        580        590        600 
TELDNFDYAN LYEPNDTFTT ANLFNHSLNS LMPEISTPSF FGGFRNENTI NNNDSKNLVT 

       610        620        630        640        650        660 
SLEDSYEDKQ SVITDTTMDE NNKTSTINNS TDTLIKPSKE NGTVKENKSS ANSTSAPSSS 

       670        680        690        700        710        720 
QNRASTILND HSNGKSDLKY VNYQSLLDSH CFYNHPSSPN LQSTSFSSAA PFSGISQASD 

       730        740        750        760        770        780 
IFDYENEDSD SNQIAGEIDN NSFPPHFYLD EDDKSACLSD DALIDHHRNT NPFINTFSSS 

       790 
PPILSQEVDR WRL 

« Hide

References

« Hide 'large scale' references
[1]"GAC1 may encode a regulatory subunit for protein phosphatase type 1 in Saccharomyces cerevisiae."
Francois J.M., Thompson-Jaeger S., Skroch J., Zellenka U., Spevak W., Tatchell K.
EMBO J. 11:87-96(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XV."
Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A., Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B., Dang V.-D. expand/collapse author list , de Haan M., Delius H., Durand P., Fairhead C., Feldmann H., Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E., Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U., Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B., Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A., Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C., Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G., Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B., Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F., Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E., Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I., Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H., Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.
Nature 387:98-102(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-415 AND SER-424, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[5]"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.
Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X63941 Genomic DNA. Translation: CAA45371.1.
Z75086 Genomic DNA. Translation: CAA99387.1.
BK006948 Genomic DNA. Translation: DAA10950.1.
PIRS67070.
RefSeqNP_014821.3. NM_001183597.3.

3D structure databases

ProteinModelPortalP28006.
SMRP28006. Positions 258-365.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid34573. 27 interactions.
DIPDIP-2375N.
IntActP28006. 9 interactions.
MINTMINT-554233.
STRING4932.YOR178C.

Protein family/group databases

CAZyCBM21. Carbohydrate-Binding Module Family 21.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYOR178C; YOR178C; YOR178C.
GeneID854350.
KEGGsce:YOR178C.

Organism-specific databases

CYGDYOR178c.
SGDS000005704. GAC1.

Phylogenomic databases

eggNOGNOG257148.
GeneTreeENSGT00530000068231.
OrthoDBEOG7G7M21.

Enzyme and pathway databases

BioCycYEAST:G3O-33690-MONOMER.

Gene expression databases

GenevestigatorP28006.

Family and domain databases

InterProIPR005036. CBM_21.
[Graphical view]
PfamPF03370. CBM_21. 1 hit.
[Graphical view]
PROSITEPS51159. CBM21. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio976437.

Entry information

Entry nameGAC1_YEAST
AccessionPrimary (citable) accession number: P28006
Secondary accession number(s): D6W2N4, Q08551
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: November 1, 1997
Last modified: July 9, 2014
This is version 104 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XV

Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families