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P27999

- RPB9_YEAST

UniProt

P27999 - RPB9_YEAST

Protein

DNA-directed RNA polymerase II subunit RPB9

Gene

RPB9

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 159 (01 Oct 2014)
      Sequence version 1 (01 Aug 1992)
      Previous versions | rss
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    Functioni

    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template. Involved in the regulation of transcription elongation. Involved in DNA repair of damage in the transcribed strand. Mediates a transcription-coupled repair (TCR) subpathway of nucleotide excision repair (NER).1 Publication

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi7 – 71Zinc 1
    Metal bindingi10 – 101Zinc 1
    Metal bindingi29 – 291Zinc 1
    Metal bindingi32 – 321Zinc 1
    Metal bindingi75 – 751Zinc 2
    Metal bindingi78 – 781Zinc 2
    Metal bindingi103 – 1031Zinc 2
    Metal bindingi106 – 1061Zinc 2

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri7 – 3226C4-typeSequence AnalysisAdd
    BLAST
    Zinc fingeri71 – 11141TFIIS-typePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: InterPro
    2. DNA-directed RNA polymerase activity Source: UniProtKB-KW
    3. zinc ion binding Source: InterPro

    GO - Biological processi

    1. maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter Source: SGD
    2. transcription, RNA-templated Source: GOC
    3. transcription-coupled nucleotide-excision repair Source: SGD
    4. transcription from RNA polymerase II promoter Source: SGD
    5. transcription initiation from RNA polymerase II promoter Source: SGD

    Keywords - Biological processi

    DNA damage, DNA repair, Transcription

    Keywords - Ligandi

    Metal-binding, Zinc

    Enzyme and pathway databases

    BioCyciYEAST:G3O-30573-MONOMER.
    ReactomeiREACT_191540. mRNA Splicing - Minor Pathway.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA-directed RNA polymerase II subunit RPB9
    Short name:
    RNA polymerase II subunit B9
    Alternative name(s):
    B12.6
    DNA-directed RNA polymerase II 14.2 kDa polypeptide
    DNA-directed RNA polymerase II subunit 9
    Gene namesi
    Name:RPB9
    Ordered Locus Names:YGL070C
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome VII

    Organism-specific databases

    CYGDiYGL070c.
    SGDiS000003038. RPB9.

    Subcellular locationi

    GO - Cellular componenti

    1. DNA-directed RNA polymerase II, core complex Source: SGD

    Keywords - Cellular componenti

    DNA-directed RNA polymerase, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 122122DNA-directed RNA polymerase II subunit RPB9PRO_0000121474Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei40 – 401Phosphoserine1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    PaxDbiP27999.
    PeptideAtlasiP27999.

    Expressioni

    Gene expression databases

    GenevestigatoriP27999.

    Interactioni

    Subunit structurei

    Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.3 Publications

    Protein-protein interaction databases

    BioGridi33178. 77 interactions.
    DIPiDIP-610N.
    IntActiP27999. 17 interactions.
    MINTiMINT-474033.
    STRINGi4932.YGL070C.

    Structurei

    Secondary structure

    1
    122
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi8 – 103
    Beta strandi15 – 195
    Turni20 – 234
    Beta strandi24 – 285
    Beta strandi30 – 334
    Beta strandi35 – 373
    Beta strandi41 – 499
    Turni52 – 576
    Helixi62 – 643
    Beta strandi66 – 683
    Turni76 – 783
    Beta strandi83 – 875
    Beta strandi92 – 943
    Beta strandi99 – 1035
    Turni104 – 1063
    Beta strandi109 – 1113
    Beta strandi114 – 1163

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1I3QX-ray3.10I1-122[»]
    1I50X-ray2.80I1-122[»]
    1I6HX-ray3.30I1-122[»]
    1K83X-ray2.80I1-122[»]
    1NIKX-ray4.10I1-122[»]
    1NT9X-ray4.20I1-122[»]
    1PQVX-ray3.80I1-122[»]
    1R5UX-ray4.50I1-122[»]
    1R9SX-ray4.25I1-122[»]
    1R9TX-ray3.50I1-122[»]
    1SFOX-ray3.61I1-122[»]
    1TWAX-ray3.20I1-122[»]
    1TWCX-ray3.00I1-122[»]
    1TWFX-ray2.30I1-122[»]
    1TWGX-ray3.30I1-122[»]
    1TWHX-ray3.40I1-122[»]
    1WCMX-ray3.80I1-122[»]
    1Y1VX-ray3.80I1-122[»]
    1Y1WX-ray4.00I1-122[»]
    1Y1YX-ray4.00I1-122[»]
    1Y77X-ray4.50I1-122[»]
    2B63X-ray3.80I1-122[»]
    2B8KX-ray4.15I1-122[»]
    2E2HX-ray3.95I1-122[»]
    2E2IX-ray3.41I1-122[»]
    2E2JX-ray3.50I1-122[»]
    2JA5X-ray3.80I1-122[»]
    2JA6X-ray4.00I1-122[»]
    2JA7X-ray3.80I/U1-122[»]
    2JA8X-ray3.80I1-122[»]
    2NVQX-ray2.90I1-122[»]
    2NVTX-ray3.36I1-122[»]
    2NVXX-ray3.60I1-122[»]
    2NVYX-ray3.40I1-122[»]
    2NVZX-ray4.30I1-122[»]
    2R7ZX-ray3.80I1-122[»]
    2R92X-ray3.80I1-122[»]
    2R93X-ray4.00I1-122[»]
    2VUMX-ray3.40I1-122[»]
    2YU9X-ray3.40I1-122[»]
    3CQZX-ray2.80I1-122[»]
    3FKIX-ray3.88I1-122[»]
    3GTGX-ray3.78I1-122[»]
    3GTJX-ray3.42I1-122[»]
    3GTKX-ray3.80I1-122[»]
    3GTLX-ray3.38I1-122[»]
    3GTMX-ray3.80I1-122[»]
    3GTOX-ray4.00I1-122[»]
    3GTPX-ray3.90I1-122[»]
    3GTQX-ray3.80I1-122[»]
    3H3VX-ray4.00J1-122[»]
    3HOUX-ray3.20I/U1-122[»]
    3HOVX-ray3.50I1-122[»]
    3HOWX-ray3.60I1-122[»]
    3HOXX-ray3.65I1-122[»]
    3HOYX-ray3.40I1-122[»]
    3HOZX-ray3.65I1-122[»]
    3I4MX-ray3.70I1-122[»]
    3I4NX-ray3.90I1-122[»]
    3J0Kelectron microscopy36.00I1-122[»]
    3J1Nelectron microscopy16.00I1-122[»]
    3K1FX-ray4.30I1-122[»]
    3K7AX-ray3.80I1-122[»]
    3M3YX-ray3.18I1-122[»]
    3M4OX-ray3.57I1-122[»]
    3PO2X-ray3.30I1-122[»]
    3PO3X-ray3.30I1-122[»]
    3QT1X-ray4.30I1-87[»]
    3RZDX-ray3.30I1-122[»]
    3RZOX-ray3.00I1-122[»]
    3S14X-ray2.85I1-122[»]
    3S15X-ray3.30I1-122[»]
    3S16X-ray3.24I1-122[»]
    3S17X-ray3.20I1-122[»]
    3S1MX-ray3.13I1-122[»]
    3S1NX-ray3.10I1-122[»]
    3S1QX-ray3.30I1-122[»]
    3S1RX-ray3.20I1-122[»]
    3S2DX-ray3.20I1-122[»]
    3S2HX-ray3.30I1-122[»]
    4A3BX-ray3.50I1-122[»]
    4A3CX-ray3.50I1-122[»]
    4A3DX-ray3.40I1-122[»]
    4A3EX-ray3.40I1-122[»]
    4A3FX-ray3.50I1-122[»]
    4A3GX-ray3.50I1-122[»]
    4A3IX-ray3.80I1-122[»]
    4A3JX-ray3.70I1-122[»]
    4A3KX-ray3.50I1-122[»]
    4A3LX-ray3.50I1-122[»]
    4A3MX-ray3.90I1-122[»]
    4A93X-ray3.40I1-122[»]
    4BBRX-ray3.40I1-122[»]
    4BBSX-ray3.60I1-122[»]
    4BXXX-ray3.28I1-122[»]
    4BXZX-ray4.80I1-122[»]
    4BY1X-ray3.60I1-122[»]
    4BY7X-ray3.15I1-122[»]
    ProteinModelPortaliP27999.
    SMRiP27999. Positions 1-122.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP27999.

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 TFIIS-type zinc finger.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri7 – 3226C4-typeSequence AnalysisAdd
    BLAST
    Zinc fingeri71 – 11141TFIIS-typePROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Zinc-finger

    Phylogenomic databases

    eggNOGiCOG1594.
    GeneTreeiENSGT00550000075063.
    HOGENOMiHOG000228134.
    KOiK03017.
    OMAiMHEIDEL.
    OrthoDBiEOG7B05RW.

    Family and domain databases

    InterProiIPR019761. DNA-dir_RNA_pol-M_15_CS.
    IPR001529. DNA-dir_RNA_pol_M/15kDasu.
    IPR012164. DNA-dir_RNApol_C11.
    IPR001222. Znf_TFIIS.
    [Graphical view]
    PfamiPF02150. RNA_POL_M_15KD. 1 hit.
    PF01096. TFIIS_C. 1 hit.
    [Graphical view]
    PIRSFiPIRSF005586. RNApol_RpoM. 1 hit.
    SMARTiSM00661. RPOL9. 1 hit.
    SM00440. ZnF_C2C2. 1 hit.
    [Graphical view]
    PROSITEiPS01030. RNA_POL_M_15KD. 1 hit.
    PS00466. ZF_TFIIS_1. 1 hit.
    PS51133. ZF_TFIIS_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P27999-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTTFRFCRDC NNMLYPREDK ENNRLLFECR TCSYVEEAGS PLVYRHELIT    50
    NIGETAGVVQ DIGSDPTLPR SDRECPKCHS RENVFFQSQQ RRKDTSMVLF 100
    FVCLSCSHIF TSDQKNKRTQ FS 122
    Length:122
    Mass (Da):14,288
    Last modified:August 1, 1992 - v1
    Checksum:iA80D69678A722881
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M73060 Genomic DNA. Translation: AAA34997.1.
    Z72592 Genomic DNA. Translation: CAA96774.1.
    AY557799 Genomic DNA. Translation: AAS56125.1.
    BK006941 Genomic DNA. Translation: DAA08033.1.
    PIRiA41016. RNBY29.
    RefSeqiNP_011445.1. NM_001180935.1.

    Genome annotation databases

    EnsemblFungiiYGL070C; YGL070C; YGL070C.
    GeneIDi852810.
    KEGGisce:YGL070C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M73060 Genomic DNA. Translation: AAA34997.1 .
    Z72592 Genomic DNA. Translation: CAA96774.1 .
    AY557799 Genomic DNA. Translation: AAS56125.1 .
    BK006941 Genomic DNA. Translation: DAA08033.1 .
    PIRi A41016. RNBY29.
    RefSeqi NP_011445.1. NM_001180935.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1I3Q X-ray 3.10 I 1-122 [» ]
    1I50 X-ray 2.80 I 1-122 [» ]
    1I6H X-ray 3.30 I 1-122 [» ]
    1K83 X-ray 2.80 I 1-122 [» ]
    1NIK X-ray 4.10 I 1-122 [» ]
    1NT9 X-ray 4.20 I 1-122 [» ]
    1PQV X-ray 3.80 I 1-122 [» ]
    1R5U X-ray 4.50 I 1-122 [» ]
    1R9S X-ray 4.25 I 1-122 [» ]
    1R9T X-ray 3.50 I 1-122 [» ]
    1SFO X-ray 3.61 I 1-122 [» ]
    1TWA X-ray 3.20 I 1-122 [» ]
    1TWC X-ray 3.00 I 1-122 [» ]
    1TWF X-ray 2.30 I 1-122 [» ]
    1TWG X-ray 3.30 I 1-122 [» ]
    1TWH X-ray 3.40 I 1-122 [» ]
    1WCM X-ray 3.80 I 1-122 [» ]
    1Y1V X-ray 3.80 I 1-122 [» ]
    1Y1W X-ray 4.00 I 1-122 [» ]
    1Y1Y X-ray 4.00 I 1-122 [» ]
    1Y77 X-ray 4.50 I 1-122 [» ]
    2B63 X-ray 3.80 I 1-122 [» ]
    2B8K X-ray 4.15 I 1-122 [» ]
    2E2H X-ray 3.95 I 1-122 [» ]
    2E2I X-ray 3.41 I 1-122 [» ]
    2E2J X-ray 3.50 I 1-122 [» ]
    2JA5 X-ray 3.80 I 1-122 [» ]
    2JA6 X-ray 4.00 I 1-122 [» ]
    2JA7 X-ray 3.80 I/U 1-122 [» ]
    2JA8 X-ray 3.80 I 1-122 [» ]
    2NVQ X-ray 2.90 I 1-122 [» ]
    2NVT X-ray 3.36 I 1-122 [» ]
    2NVX X-ray 3.60 I 1-122 [» ]
    2NVY X-ray 3.40 I 1-122 [» ]
    2NVZ X-ray 4.30 I 1-122 [» ]
    2R7Z X-ray 3.80 I 1-122 [» ]
    2R92 X-ray 3.80 I 1-122 [» ]
    2R93 X-ray 4.00 I 1-122 [» ]
    2VUM X-ray 3.40 I 1-122 [» ]
    2YU9 X-ray 3.40 I 1-122 [» ]
    3CQZ X-ray 2.80 I 1-122 [» ]
    3FKI X-ray 3.88 I 1-122 [» ]
    3GTG X-ray 3.78 I 1-122 [» ]
    3GTJ X-ray 3.42 I 1-122 [» ]
    3GTK X-ray 3.80 I 1-122 [» ]
    3GTL X-ray 3.38 I 1-122 [» ]
    3GTM X-ray 3.80 I 1-122 [» ]
    3GTO X-ray 4.00 I 1-122 [» ]
    3GTP X-ray 3.90 I 1-122 [» ]
    3GTQ X-ray 3.80 I 1-122 [» ]
    3H3V X-ray 4.00 J 1-122 [» ]
    3HOU X-ray 3.20 I/U 1-122 [» ]
    3HOV X-ray 3.50 I 1-122 [» ]
    3HOW X-ray 3.60 I 1-122 [» ]
    3HOX X-ray 3.65 I 1-122 [» ]
    3HOY X-ray 3.40 I 1-122 [» ]
    3HOZ X-ray 3.65 I 1-122 [» ]
    3I4M X-ray 3.70 I 1-122 [» ]
    3I4N X-ray 3.90 I 1-122 [» ]
    3J0K electron microscopy 36.00 I 1-122 [» ]
    3J1N electron microscopy 16.00 I 1-122 [» ]
    3K1F X-ray 4.30 I 1-122 [» ]
    3K7A X-ray 3.80 I 1-122 [» ]
    3M3Y X-ray 3.18 I 1-122 [» ]
    3M4O X-ray 3.57 I 1-122 [» ]
    3PO2 X-ray 3.30 I 1-122 [» ]
    3PO3 X-ray 3.30 I 1-122 [» ]
    3QT1 X-ray 4.30 I 1-87 [» ]
    3RZD X-ray 3.30 I 1-122 [» ]
    3RZO X-ray 3.00 I 1-122 [» ]
    3S14 X-ray 2.85 I 1-122 [» ]
    3S15 X-ray 3.30 I 1-122 [» ]
    3S16 X-ray 3.24 I 1-122 [» ]
    3S17 X-ray 3.20 I 1-122 [» ]
    3S1M X-ray 3.13 I 1-122 [» ]
    3S1N X-ray 3.10 I 1-122 [» ]
    3S1Q X-ray 3.30 I 1-122 [» ]
    3S1R X-ray 3.20 I 1-122 [» ]
    3S2D X-ray 3.20 I 1-122 [» ]
    3S2H X-ray 3.30 I 1-122 [» ]
    4A3B X-ray 3.50 I 1-122 [» ]
    4A3C X-ray 3.50 I 1-122 [» ]
    4A3D X-ray 3.40 I 1-122 [» ]
    4A3E X-ray 3.40 I 1-122 [» ]
    4A3F X-ray 3.50 I 1-122 [» ]
    4A3G X-ray 3.50 I 1-122 [» ]
    4A3I X-ray 3.80 I 1-122 [» ]
    4A3J X-ray 3.70 I 1-122 [» ]
    4A3K X-ray 3.50 I 1-122 [» ]
    4A3L X-ray 3.50 I 1-122 [» ]
    4A3M X-ray 3.90 I 1-122 [» ]
    4A93 X-ray 3.40 I 1-122 [» ]
    4BBR X-ray 3.40 I 1-122 [» ]
    4BBS X-ray 3.60 I 1-122 [» ]
    4BXX X-ray 3.28 I 1-122 [» ]
    4BXZ X-ray 4.80 I 1-122 [» ]
    4BY1 X-ray 3.60 I 1-122 [» ]
    4BY7 X-ray 3.15 I 1-122 [» ]
    ProteinModelPortali P27999.
    SMRi P27999. Positions 1-122.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 33178. 77 interactions.
    DIPi DIP-610N.
    IntActi P27999. 17 interactions.
    MINTi MINT-474033.
    STRINGi 4932.YGL070C.

    Proteomic databases

    PaxDbi P27999.
    PeptideAtlasi P27999.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YGL070C ; YGL070C ; YGL070C .
    GeneIDi 852810.
    KEGGi sce:YGL070C.

    Organism-specific databases

    CYGDi YGL070c.
    SGDi S000003038. RPB9.

    Phylogenomic databases

    eggNOGi COG1594.
    GeneTreei ENSGT00550000075063.
    HOGENOMi HOG000228134.
    KOi K03017.
    OMAi MHEIDEL.
    OrthoDBi EOG7B05RW.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-30573-MONOMER.
    Reactomei REACT_191540. mRNA Splicing - Minor Pathway.

    Miscellaneous databases

    EvolutionaryTracei P27999.
    NextBioi 972339.
    PROi P27999.

    Gene expression databases

    Genevestigatori P27999.

    Family and domain databases

    InterProi IPR019761. DNA-dir_RNA_pol-M_15_CS.
    IPR001529. DNA-dir_RNA_pol_M/15kDasu.
    IPR012164. DNA-dir_RNApol_C11.
    IPR001222. Znf_TFIIS.
    [Graphical view ]
    Pfami PF02150. RNA_POL_M_15KD. 1 hit.
    PF01096. TFIIS_C. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF005586. RNApol_RpoM. 1 hit.
    SMARTi SM00661. RPOL9. 1 hit.
    SM00440. ZnF_C2C2. 1 hit.
    [Graphical view ]
    PROSITEi PS01030. RNA_POL_M_15KD. 1 hit.
    PS00466. ZF_TFIIS_1. 1 hit.
    PS51133. ZF_TFIIS_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Yeast RNA polymerase II subunit RPB9 is essential for growth at temperature extremes."
      Woychik N.A., Lane W.S., Young R.A.
      J. Biol. Chem. 266:19053-19055(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 46-62.
    2. "Sequence analysis of 203 kilobases from Saccharomyces cerevisiae chromosome VII."
      Rieger M., Brueckner M., Schaefer M., Mueller-Auer S.
      Yeast 13:1077-1090(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
      Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E.
      , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
      Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    5. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    6. "RNA polymerase II subunit Rpb9 regulates transcription elongation in vivo."
      Hemming S.A., Jansma D.B., Macgregor P.F., Goryachev A., Friesen J.D., Edwards A.M.
      J. Biol. Chem. 275:35506-35511(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: INVOLVEMENT IN TRANSCRIPTION ELONGATION.
    7. "Rpb4 and Rpb9 mediate subpathways of transcription-coupled DNA repair in Saccharomyces cerevisiae."
      Li S., Smerdon M.J.
      EMBO J. 21:5921-5929(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION IN DNA REPAIR.
    8. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    9. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
      Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
      Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-40, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    10. "RNA polymerase II/TFIIF structure and conserved organization of the initiation complex."
      Chung W.H., Craighead J.L., Chang W.H., Ezeokonkwo C., Bareket-Samish A., Kornberg R.D., Asturias F.J.
      Mol. Cell 12:1003-1013(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: ELECTRON MICROSCOPY OF THE RNA POL II/TFIIF COMPLEX.
    11. "Structural basis of transcription: RNA polymerase II at 2.8 A resolution."
      Cramer P., Bushnell D.A., Kornberg R.D.
      Science 292:1863-1876(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF THE RNA POL II CORE COMPLEX.
    12. "Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution."
      Gnatt A.L., Cramer P., Fu J., Bushnell D.A., Kornberg R.D.
      Science 292:1876-1882(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (3.3 ANGSTROMS) OF THE RNA POL II CORE COMPLEX.
    13. "Structural basis of transcription: alpha-amanitin-RNA polymerase II cocrystal at 2.8 A resolution."
      Bushnell D.A., Cramer P., Kornberg R.D.
      Proc. Natl. Acad. Sci. U.S.A. 99:1218-1222(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF THE RNA POL II CORE COMPLEX IN COMPLEX WITH ALPHA-AMANITIN.
    14. "Architecture of the RNA polymerase II-TFIIS complex and implications for mRNA cleavage."
      Kettenberger H., Armache K.J., Cramer P.
      Cell 114:347-357(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (3.8 ANGSTROMS) OF THE RNA POL II COMPLEX IN COMPLEX WITH DST1.
    15. "Architecture of initiation-competent 12-subunit RNA polymerase II."
      Armache K.J., Kettenberger H., Cramer P.
      Proc. Natl. Acad. Sci. U.S.A. 100:6964-6968(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (4.2 ANGSTROMS) OF THE RNA POL II COMPLEX.
    16. "Complete, 12-subunit RNA polymerase II at 4.1-A resolution: implications for the initiation of transcription."
      Bushnell D.A., Kornberg R.D.
      Proc. Natl. Acad. Sci. U.S.A. 100:6969-6973(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (4.1 ANGSTROMS) OF THE RNA POL II CORE COMPLEX.
    17. "Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center."
      Westover K.D., Bushnell D.A., Kornberg R.D.
      Cell 119:481-489(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF THE RNA POL II CORE COMPLEX.
    18. "Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS."
      Kettenberger H., Armache K.J., Cramer P.
      Mol. Cell 16:955-965(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (4.5 ANGSTROMS).
    19. "Structural basis of transcription: an RNA polymerase II-TFIIB cocrystal at 4.5 Angstroms."
      Bushnell D.A., Westover K.D., Davis R.E., Kornberg R.D.
      Science 303:983-988(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (4.5 ANGSTROMS) OF THE RNA POL II CORE COMPLEX.
    20. "Structures of complete RNA polymerase II and its subcomplex, Rpb4/7."
      Armache K.J., Mitterweger S., Meinhart A., Cramer P.
      J. Biol. Chem. 280:7131-7134(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (3.8 ANGSTROMS) OF THE RNA POL II COMPLEX.
    21. "Structure of an RNA polymerase II-RNA inhibitor complex elucidates transcription regulation by noncoding RNAs."
      Kettenberger H., Eisenfuhr A., Brueckner F., Theis M., Famulok M., Cramer P.
      Nat. Struct. Mol. Biol. 13:44-48(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (3.8 ANGSTROMS) OF THE RNA POL II COMPLEX IN COMPLEX WITH INHIBITING NON-CODING RNA.
    22. "Phasing RNA polymerase II using intrinsically bound Zn atoms: an updated structural model."
      Meyer P.A., Ye P., Zhang M., Suh M.H., Fu J.
      Structure 14:973-982(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (4.15 ANGSTROMS) OF THE RNA POL II COMPLEX.

    Entry informationi

    Entry nameiRPB9_YEAST
    AccessioniPrimary (citable) accession number: P27999
    Secondary accession number(s): D6VU72
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 1, 1992
    Last sequence update: August 1, 1992
    Last modified: October 1, 2014
    This is version 159 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 2440 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. SIMILARITY comments
      Index of protein domains and families
    3. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    4. Yeast chromosome VII
      Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

    External Data

    Dasty 3