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P27951

- BAG_STRAG

UniProt

P27951 - BAG_STRAG

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Protein

IgA FC receptor

Gene
bag
Organism
Streptococcus agalactiae
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Keywords - Molecular functioni

Receptor

Names & Taxonomyi

Protein namesi
Recommended name:
IgA FC receptor
Alternative name(s):
Beta antigen
Short name:
B antigen
Gene namesi
Name:bag
OrganismiStreptococcus agalactiae
Taxonomic identifieri1311 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Subcellular locationi

Secretedcell wall; Peptidoglycan-anchor Reviewed prediction

GO - Cellular componenti

  1. cell wall Source: UniProtKB-SubCell
  2. extracellular region Source: UniProtKB-KW
  3. membrane Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cell wall, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 37371 PublicationAdd
BLAST
Chaini38 – 11351098IgA FC receptorPRO_0000005595Add
BLAST
Propeptidei1136 – 116429Removed by sortase Reviewed predictionPRO_0000005596Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1135 – 11351Pentaglycyl murein peptidoglycan amidated threonine Reviewed prediction

Keywords - PTMi

Peptidoglycan-anchor

Structurei

3D structure databases

ProteinModelPortaliP27951.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini434 – 534101Ig-likeAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni199 – 438240IgA-binding Reviewed predictionAdd
BLAST
Regioni439 – 826388IgA-binding Reviewed predictionAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi1132 – 11365LPXTG sorting signal Reviewed prediction

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi827 – 944118Pro-richAdd
BLAST

Sequence similaritiesi

Keywords - Domaini

Immunoglobulin domain, Signal

Phylogenomic databases

eggNOGiCOG5523.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR019948. Gram-positive_anchor.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR019931. LPXTG_anchor.
IPR007756. RICH.
IPR005877. YSIRK_signal_dom.
[Graphical view]
PfamiPF00746. Gram_pos_anchor. 1 hit.
PF05062. RICH. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view]
ProDomiPD008292. RICH. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00409. IG. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P27951-1 [UniParc]FASTAAdd to Basket

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MFKSNYERKM RYSIRKFSVG VASVAVASLF MGSVAHASEL VKDDSVKTTE     50
VAAKPYPSMA QTDQGNNSSS SELETTKMEI PTTDIKKAVE PVEKTAGETS 100
ATDTGKREKQ LQQWKNNLKN DVDNTILSHE QKNEFKTKID ETNDSDALLE 150
LENQFNETNR LLHIKQHEEV EKDKKAKQQK TLKQSDTKVD LSNIDKELNH 200
QKSQVEKMAE QKGITNEDKD SMLKKIEDIR KQAQQADKKE DAEVKVREEL 250
GKLFSSTKAG LDQEIQEHVK KETSSEENTQ KVDEHYANSL QNLAQKSLEE 300
LDKATTNEQA TQVKNQFLEN AQKLKEIQPL IKETNVKLYK AMSESLEQVE 350
KELKHNSEAN LEDLVAKSKE IVREYEGKLN QSKNLPELKQ LEEEAHSKLK 400
QVVEDFRKKF KTSEQVTPKK RVKRDLAANE NNQQKIELTV SPENITVYEG 450
EDVKFTVTAK SDSKTTLDFS DLLTKYNPSV SDRISTNYKT NTDNHKIAEI 500
TIKNLKLNES QTVTLKAKDD SGNVVEKTFT ITVQKKEEKQ VPKTPEQKDS 550
KTEEKVPQEP KSNDKNQLQE LIKSAQQELE KLEKAIKELM EQPEIPSNPE 600
YGIQKSIWES QKEPIQEAIT SFKKIIGDSS SKYYTEHYFN KYKSDFMNYQ 650
LHAQMEMLTR KVVQYMNKYP DNAEIKKIFE SDMKRTKEDN YGSLENDALK 700
GYFEKYFLTP FNKIKQIVDD LDKKVEQDQP APIPENSEMD QAKEKAKIAV 750
SKYMSKVLDG VHQHLQKKNN SKIVDLFKEL EAIKQQTIFD IDNAKTEVEI 800
DNLVHDAFSK MNATVAKFQK GLETNTPETP DTPKIPELPQ APDTPQAPDT 850
PHVPESPKAP EAPRVPESPK TPEAPHVPES PKAPEAPRVP ESPKTPEAPH 900
VPESPKTPEA PKIPEPPKTP DVPKLPDVPK LPDVPKLPDA PKLPDGLNKV 950
GQAVFTSTDG NTKVTVVFDK PTDADKLHLK EVTTKELADK IAHKTGGGTV 1000
RVFDLSLSKG GKETHVNGER TVRLALGQTG SDVHVYHVKE NGDLERIPSK 1050
VENGQVVFKT NHFSLFAIKT LSKDQNVTPP KQTKPSTQGS QVEIAESQTG 1100
KFQSKAANHK ALATGNETVA KGNPTSTTEK KLPYTGVASN LVLEIMGLLG 1150
LIGTSFIAMK RRKS 1164
Length:1,164
Mass (Da):131,052
Last modified:August 1, 1992 - v1
Checksum:i65DE94AF720A5474
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X59771 Genomic DNA. Translation: CAA42442.1.
PIRiS15330. FCSOAG.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X59771 Genomic DNA. Translation: CAA42442.1 .
PIRi S15330. FCSOAG.

3D structure databases

ProteinModelPortali P27951.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

eggNOGi COG5523.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
InterProi IPR019948. Gram-positive_anchor.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR019931. LPXTG_anchor.
IPR007756. RICH.
IPR005877. YSIRK_signal_dom.
[Graphical view ]
Pfami PF00746. Gram_pos_anchor. 1 hit.
PF05062. RICH. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view ]
ProDomi PD008292. RICH. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SMARTi SM00409. IG. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEi PS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The IgA-binding beta antigen of the c protein complex of Group B streptococci: sequence determination of its gene and detection of two binding regions."
    Jerlstroem P.G., Chhatwal G.S., Timmis K.N.
    Mol. Microbiol. 5:843-849(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 38-48.
    Strain: LA239.
  2. "Members of the immunoglobulin superfamily in bacteria."
    Bateman A., Eddy S.R., Chothia C.
    Protein Sci. 5:1939-1942(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION OF IG-LIKE DOMAIN.

Entry informationi

Entry nameiBAG_STRAG
AccessioniPrimary (citable) accession number: P27951
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: September 3, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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