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P27951

- BAG_STRAG

UniProt

P27951 - BAG_STRAG

Protein

IgA FC receptor

Gene

bag

Organism
Streptococcus agalactiae
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 1 (01 Aug 1992)
      Previous versions | rss
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    Functioni

    Keywords - Molecular functioni

    Receptor

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    IgA FC receptor
    Alternative name(s):
    Beta antigen
    Short name:
    B antigen
    Gene namesi
    Name:bag
    OrganismiStreptococcus agalactiae
    Taxonomic identifieri1311 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

    Subcellular locationi

    Secretedcell wall PROSITE-ProRule annotation; Peptidoglycan-anchor PROSITE-ProRule annotation

    GO - Cellular componenti

    1. cell wall Source: UniProtKB-SubCell
    2. extracellular region Source: UniProtKB-KW
    3. membrane Source: InterPro

    Keywords - Cellular componenti

    Cell wall, Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 37371 PublicationAdd
    BLAST
    Chaini38 – 11351098IgA FC receptorPRO_0000005595Add
    BLAST
    Propeptidei1136 – 116429Removed by sortasePROSITE-ProRule annotationPRO_0000005596Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei1135 – 11351Pentaglycyl murein peptidoglycan amidated threoninePROSITE-ProRule annotation

    Keywords - PTMi

    Peptidoglycan-anchor

    Structurei

    3D structure databases

    ProteinModelPortaliP27951.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini434 – 534101Ig-likeAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni199 – 438240IgA-bindingSequence AnalysisAdd
    BLAST
    Regioni439 – 826388IgA-bindingSequence AnalysisAdd
    BLAST

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi1132 – 11365LPXTG sorting signalPROSITE-ProRule annotation

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi827 – 944118Pro-richAdd
    BLAST

    Sequence similaritiesi

    Keywords - Domaini

    Immunoglobulin domain, Signal

    Phylogenomic databases

    eggNOGiCOG5523.

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    InterProiIPR019948. Gram-positive_anchor.
    IPR013783. Ig-like_fold.
    IPR003599. Ig_sub.
    IPR019931. LPXTG_anchor.
    IPR007756. RICH.
    IPR005877. YSIRK_signal_dom.
    [Graphical view]
    PfamiPF00746. Gram_pos_anchor. 1 hit.
    PF05062. RICH. 1 hit.
    PF04650. YSIRK_signal. 1 hit.
    [Graphical view]
    ProDomiPD008292. RICH. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SMARTiSM00409. IG. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
    TIGR01168. YSIRK_signal. 1 hit.
    PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P27951-1 [UniParc]FASTAAdd to Basket

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    MFKSNYERKM RYSIRKFSVG VASVAVASLF MGSVAHASEL VKDDSVKTTE     50
    VAAKPYPSMA QTDQGNNSSS SELETTKMEI PTTDIKKAVE PVEKTAGETS 100
    ATDTGKREKQ LQQWKNNLKN DVDNTILSHE QKNEFKTKID ETNDSDALLE 150
    LENQFNETNR LLHIKQHEEV EKDKKAKQQK TLKQSDTKVD LSNIDKELNH 200
    QKSQVEKMAE QKGITNEDKD SMLKKIEDIR KQAQQADKKE DAEVKVREEL 250
    GKLFSSTKAG LDQEIQEHVK KETSSEENTQ KVDEHYANSL QNLAQKSLEE 300
    LDKATTNEQA TQVKNQFLEN AQKLKEIQPL IKETNVKLYK AMSESLEQVE 350
    KELKHNSEAN LEDLVAKSKE IVREYEGKLN QSKNLPELKQ LEEEAHSKLK 400
    QVVEDFRKKF KTSEQVTPKK RVKRDLAANE NNQQKIELTV SPENITVYEG 450
    EDVKFTVTAK SDSKTTLDFS DLLTKYNPSV SDRISTNYKT NTDNHKIAEI 500
    TIKNLKLNES QTVTLKAKDD SGNVVEKTFT ITVQKKEEKQ VPKTPEQKDS 550
    KTEEKVPQEP KSNDKNQLQE LIKSAQQELE KLEKAIKELM EQPEIPSNPE 600
    YGIQKSIWES QKEPIQEAIT SFKKIIGDSS SKYYTEHYFN KYKSDFMNYQ 650
    LHAQMEMLTR KVVQYMNKYP DNAEIKKIFE SDMKRTKEDN YGSLENDALK 700
    GYFEKYFLTP FNKIKQIVDD LDKKVEQDQP APIPENSEMD QAKEKAKIAV 750
    SKYMSKVLDG VHQHLQKKNN SKIVDLFKEL EAIKQQTIFD IDNAKTEVEI 800
    DNLVHDAFSK MNATVAKFQK GLETNTPETP DTPKIPELPQ APDTPQAPDT 850
    PHVPESPKAP EAPRVPESPK TPEAPHVPES PKAPEAPRVP ESPKTPEAPH 900
    VPESPKTPEA PKIPEPPKTP DVPKLPDVPK LPDVPKLPDA PKLPDGLNKV 950
    GQAVFTSTDG NTKVTVVFDK PTDADKLHLK EVTTKELADK IAHKTGGGTV 1000
    RVFDLSLSKG GKETHVNGER TVRLALGQTG SDVHVYHVKE NGDLERIPSK 1050
    VENGQVVFKT NHFSLFAIKT LSKDQNVTPP KQTKPSTQGS QVEIAESQTG 1100
    KFQSKAANHK ALATGNETVA KGNPTSTTEK KLPYTGVASN LVLEIMGLLG 1150
    LIGTSFIAMK RRKS 1164
    Length:1,164
    Mass (Da):131,052
    Last modified:August 1, 1992 - v1
    Checksum:i65DE94AF720A5474
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X59771 Genomic DNA. Translation: CAA42442.1.
    PIRiS15330. FCSOAG.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X59771 Genomic DNA. Translation: CAA42442.1 .
    PIRi S15330. FCSOAG.

    3D structure databases

    ProteinModelPortali P27951.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    eggNOGi COG5523.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    InterProi IPR019948. Gram-positive_anchor.
    IPR013783. Ig-like_fold.
    IPR003599. Ig_sub.
    IPR019931. LPXTG_anchor.
    IPR007756. RICH.
    IPR005877. YSIRK_signal_dom.
    [Graphical view ]
    Pfami PF00746. Gram_pos_anchor. 1 hit.
    PF05062. RICH. 1 hit.
    PF04650. YSIRK_signal. 1 hit.
    [Graphical view ]
    ProDomi PD008292. RICH. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SMARTi SM00409. IG. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01167. LPXTG_anchor. 1 hit.
    TIGR01168. YSIRK_signal. 1 hit.
    PROSITEi PS50847. GRAM_POS_ANCHORING. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The IgA-binding beta antigen of the c protein complex of Group B streptococci: sequence determination of its gene and detection of two binding regions."
      Jerlstroem P.G., Chhatwal G.S., Timmis K.N.
      Mol. Microbiol. 5:843-849(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 38-48.
      Strain: LA239.
    2. "Members of the immunoglobulin superfamily in bacteria."
      Bateman A., Eddy S.R., Chothia C.
      Protein Sci. 5:1939-1942(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION OF IG-LIKE DOMAIN.

    Entry informationi

    Entry nameiBAG_STRAG
    AccessioniPrimary (citable) accession number: P27951
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 1, 1992
    Last sequence update: August 1, 1992
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3