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P27951

- BAG_STRAG

UniProt

P27951 - BAG_STRAG

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Protein

IgA FC receptor

Gene

bag

Organism
Streptococcus agalactiae
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Keywords - Molecular functioni

Receptor

Names & Taxonomyi

Protein namesi
Recommended name:
IgA FC receptor
Alternative name(s):
Beta antigen
Short name:
B antigen
Gene namesi
Name:bag
OrganismiStreptococcus agalactiae
Taxonomic identifieri1311 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Subcellular locationi

Secretedcell wall PROSITE-ProRule annotation; Peptidoglycan-anchor PROSITE-ProRule annotation

GO - Cellular componenti

  1. cell wall Source: UniProtKB-KW
  2. extracellular region Source: UniProtKB-KW
  3. membrane Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cell wall, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 37371 PublicationAdd
BLAST
Chaini38 – 11351098IgA FC receptorPRO_0000005595Add
BLAST
Propeptidei1136 – 116429Removed by sortasePROSITE-ProRule annotationPRO_0000005596Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1135 – 11351Pentaglycyl murein peptidoglycan amidated threoninePROSITE-ProRule annotation

Keywords - PTMi

Peptidoglycan-anchor

Structurei

3D structure databases

ProteinModelPortaliP27951.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini434 – 534101Ig-likeAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni199 – 438240IgA-bindingSequence AnalysisAdd
BLAST
Regioni439 – 826388IgA-bindingSequence AnalysisAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi1132 – 11365LPXTG sorting signalPROSITE-ProRule annotation

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi827 – 944118Pro-richAdd
BLAST

Sequence similaritiesi

Keywords - Domaini

Immunoglobulin domain, Signal

Phylogenomic databases

eggNOGiCOG5523.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR019948. Gram-positive_anchor.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR019931. LPXTG_anchor.
IPR007756. RICH.
IPR005877. YSIRK_signal_dom.
[Graphical view]
PfamiPF00746. Gram_pos_anchor. 1 hit.
PF05062. RICH. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view]
ProDomiPD008292. RICH. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00409. IG. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P27951-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFKSNYERKM RYSIRKFSVG VASVAVASLF MGSVAHASEL VKDDSVKTTE
60 70 80 90 100
VAAKPYPSMA QTDQGNNSSS SELETTKMEI PTTDIKKAVE PVEKTAGETS
110 120 130 140 150
ATDTGKREKQ LQQWKNNLKN DVDNTILSHE QKNEFKTKID ETNDSDALLE
160 170 180 190 200
LENQFNETNR LLHIKQHEEV EKDKKAKQQK TLKQSDTKVD LSNIDKELNH
210 220 230 240 250
QKSQVEKMAE QKGITNEDKD SMLKKIEDIR KQAQQADKKE DAEVKVREEL
260 270 280 290 300
GKLFSSTKAG LDQEIQEHVK KETSSEENTQ KVDEHYANSL QNLAQKSLEE
310 320 330 340 350
LDKATTNEQA TQVKNQFLEN AQKLKEIQPL IKETNVKLYK AMSESLEQVE
360 370 380 390 400
KELKHNSEAN LEDLVAKSKE IVREYEGKLN QSKNLPELKQ LEEEAHSKLK
410 420 430 440 450
QVVEDFRKKF KTSEQVTPKK RVKRDLAANE NNQQKIELTV SPENITVYEG
460 470 480 490 500
EDVKFTVTAK SDSKTTLDFS DLLTKYNPSV SDRISTNYKT NTDNHKIAEI
510 520 530 540 550
TIKNLKLNES QTVTLKAKDD SGNVVEKTFT ITVQKKEEKQ VPKTPEQKDS
560 570 580 590 600
KTEEKVPQEP KSNDKNQLQE LIKSAQQELE KLEKAIKELM EQPEIPSNPE
610 620 630 640 650
YGIQKSIWES QKEPIQEAIT SFKKIIGDSS SKYYTEHYFN KYKSDFMNYQ
660 670 680 690 700
LHAQMEMLTR KVVQYMNKYP DNAEIKKIFE SDMKRTKEDN YGSLENDALK
710 720 730 740 750
GYFEKYFLTP FNKIKQIVDD LDKKVEQDQP APIPENSEMD QAKEKAKIAV
760 770 780 790 800
SKYMSKVLDG VHQHLQKKNN SKIVDLFKEL EAIKQQTIFD IDNAKTEVEI
810 820 830 840 850
DNLVHDAFSK MNATVAKFQK GLETNTPETP DTPKIPELPQ APDTPQAPDT
860 870 880 890 900
PHVPESPKAP EAPRVPESPK TPEAPHVPES PKAPEAPRVP ESPKTPEAPH
910 920 930 940 950
VPESPKTPEA PKIPEPPKTP DVPKLPDVPK LPDVPKLPDA PKLPDGLNKV
960 970 980 990 1000
GQAVFTSTDG NTKVTVVFDK PTDADKLHLK EVTTKELADK IAHKTGGGTV
1010 1020 1030 1040 1050
RVFDLSLSKG GKETHVNGER TVRLALGQTG SDVHVYHVKE NGDLERIPSK
1060 1070 1080 1090 1100
VENGQVVFKT NHFSLFAIKT LSKDQNVTPP KQTKPSTQGS QVEIAESQTG
1110 1120 1130 1140 1150
KFQSKAANHK ALATGNETVA KGNPTSTTEK KLPYTGVASN LVLEIMGLLG
1160
LIGTSFIAMK RRKS
Length:1,164
Mass (Da):131,052
Last modified:August 1, 1992 - v1
Checksum:i65DE94AF720A5474
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59771 Genomic DNA. Translation: CAA42442.1.
PIRiS15330. FCSOAG.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59771 Genomic DNA. Translation: CAA42442.1 .
PIRi S15330. FCSOAG.

3D structure databases

ProteinModelPortali P27951.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

eggNOGi COG5523.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
InterProi IPR019948. Gram-positive_anchor.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR019931. LPXTG_anchor.
IPR007756. RICH.
IPR005877. YSIRK_signal_dom.
[Graphical view ]
Pfami PF00746. Gram_pos_anchor. 1 hit.
PF05062. RICH. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view ]
ProDomi PD008292. RICH. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SMARTi SM00409. IG. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEi PS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The IgA-binding beta antigen of the c protein complex of Group B streptococci: sequence determination of its gene and detection of two binding regions."
    Jerlstroem P.G., Chhatwal G.S., Timmis K.N.
    Mol. Microbiol. 5:843-849(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 38-48.
    Strain: LA239.
  2. "Members of the immunoglobulin superfamily in bacteria."
    Bateman A., Eddy S.R., Chothia C.
    Protein Sci. 5:1939-1942(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION OF IG-LIKE DOMAIN.

Entry informationi

Entry nameiBAG_STRAG
AccessioniPrimary (citable) accession number: P27951
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: October 29, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3