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Protein

Trichome differentiation protein GL1

Gene

GL1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Transcription activator, when associated with BHLH2/EGL3/MYC146 or BHLH12/MYC1. Involved in epidermal cell fate specification in leaves. Together with TTG1 and GL3, promotes trichome formation and endoreplication. Regulates the production of a signal that induces hair (trichome) precursor cells on leaf primordia to differentiate. Binds to the WER-binding sites (WBS) promoter regions and activates the transcription of target genes (By similarity).By similarity5 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi39 – 63H-T-H motifPROSITE-ProRule annotationAdd BLAST25
DNA bindingi91 – 114H-T-H motifPROSITE-ProRule annotationAdd BLAST24

GO - Molecular functioni

GO - Biological processi

  • cell fate specification Source: TAIR
  • gibberellic acid mediated signaling pathway Source: TAIR
  • jasmonic acid mediated signaling pathway Source: TAIR
  • regulation of protein localization Source: TAIR
  • regulation of transcription by RNA polymerase II Source: GO_Central
  • regulation of trichome morphogenesis Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW
  • trichome differentiation Source: TAIR
  • trichome patterning Source: TAIR

Keywordsi

Molecular functionActivator, Developmental protein, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Trichome differentiation protein GL11 Publication
Alternative name(s):
Myb-related protein 0
Short name:
AtMYB0
Protein GLABRA 11 Publication
Protein GLABROUS 11 Publication
R2R3-MYB transcription factor GL11 Publication
Gene namesi
Name:GL11 Publication
Synonyms:MYB0
Ordered Locus Names:At3g27920Imported
ORF Names:K16N12.17Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G27920
TAIRilocus:2086475 AT3G27920

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi100G → R in gl1-65; few trichomes on leaf margins, cauline leaves, and stems. 1 Publication1
Mutagenesisi182 – 228Missing in gl1-323; few trichomes on leaf margins, cauline leaves. 1 PublicationAdd BLAST47
Mutagenesisi202 – 228Missing in gl1-2; reduced trichome density, truncated trichomes. 1 PublicationAdd BLAST27

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001970711 – 228Trichome differentiation protein GL1Add BLAST228

Proteomic databases

PaxDbiP27900

Expressioni

Tissue specificityi

Expressed in leaves, stems and flowers (PubMed:11437443). Expressed in trichome cells and in leaf primordia (PubMed:9625690).2 Publications

Developmental stagei

Ubiquitous in young leaves primordia. Becomes more prominent in developing trichome cells but disappears progressively when trichomes begin to initiate branches.1 Publication

Inductioni

Up-regulated by gibberellins (PubMed:9625690). May be regulated by GEBP and GEBP-like proteins (PubMed:12535344).2 Publications

Gene expression databases

ExpressionAtlasiP27900 baseline and differential
GenevisibleiP27900 AT

Interactioni

Subunit structurei

Homodimer and heterodimer with MYB82 (PubMed:24803498). Interacts directly with GL3 and BHLH2. Part of a complex made of GL1, GL3 or BHLH2, and TTG1. Interacts also with BHLH2/EGL3/MYC146 and BHLH12/MYC1. Interacts with MYB82 (PubMed:24803498).6 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
GL3Q9FN695EBI-1543742,EBI-533348

Protein-protein interaction databases

BioGridi7745, 10 interactors
DIPiDIP-38476N
IntActiP27900, 5 interactors
STRINGi3702.AT3G27920.1

Structurei

3D structure databases

ProteinModelPortaliP27900
SMRiP27900
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 63HTH myb-type 1PROSITE-ProRule annotationAdd BLAST53
Domaini64 – 118HTH myb-type 2PROSITE-ProRule annotationAdd BLAST55

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0048 Eukaryota
COG5147 LUCA
InParanoidiP27900
KOiK09422
OMAiEEDNILM
OrthoDBiEOG09360LV2
PhylomeDBiP27900

Family and domain databases

CDDicd00167 SANT, 2 hits
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017930 Myb_dom
IPR001005 SANT/Myb
PfamiView protein in Pfam
PF00249 Myb_DNA-binding, 2 hits
SMARTiView protein in SMART
SM00717 SANT, 2 hits
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS51294 HTH_MYB, 2 hits

Sequencei

Sequence statusi: Complete.

P27900-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIRRRDEKE NQEYKKGLWT VEEDNILMDY VLNHGTGQWN RIVRKTGLKR
60 70 80 90 100
CGKSCRLRWM NYLSPNVNKG NFTEQEEDLI IRLHKLLGNR WSLIAKRVPG
110 120 130 140 150
RTDNQVKNYW NTHLSKKLVG DYSSAVKTTG EDDDSPPSLF ITAATPSSCH
160 170 180 190 200
HQQENIYENI AKSFNGVVSA SYEDKPKQEL AQKDVLMATT NDPSHYYGNN
210 220
ALWVHDDDFE LSSLVMMNFA SGDVEYCL
Length:228
Mass (Da):26,339
Last modified:October 18, 2001 - v2
Checksum:i822A8646F446F6B9
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti130 – 132GED → VEE in strain: cv. Can-0. 3
Natural varianti148Missing in strain: cv. Kas-1, cv. Ms-0. 1 Publication1
Natural varianti149C → R in strain: cv. Aa-0, cv. An-1, cv. Bur-0, cv. Can-0, cv. Es-0, cv. Gr-1, cv. Hi-0, cv. Ita-0, cv. Kas-1, cv. Ms-0, cv. Mt-0, cv. Nd-0, cv. No-0, cv. Oy-0, cv. RLD, cv. Tsu-0, cv. Wassilewskija and cv. Yo-0. 1 Publication1
Natural varianti176P → R in strain: cv. Di-0 and cv. Landsberg erecta. 1 Publication1
Natural varianti222 – 224GDV → SDI in strain: cv. Aa-0, cv. An-1, cv. Bur-0, cv. Can-0, cv. Es-0, cv. Gr-1, cv. Hi-0, cv. Ita-0, cv. Kas-1, cv. Ms-0, cv. Mt-0, cv. Nd-0, cv. No-0, cv. Oy-0, cv. RLD, cv. Tsu-0, cv. Wassilewskija and cv. Yo-0. 3

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M79448 Genomic DNA Translation: AAC97387.1
L22786 Genomic DNA Translation: AAC97388.1
AB006078 Genomic DNA Translation: BAA86879.1
AJ243899 Genomic DNA Translation: CAB97484.1
AJ243900 Genomic DNA Translation: CAB97485.1
AF263690 Genomic DNA Translation: AAL01215.1
AF263691 Genomic DNA Translation: AAL01216.1
AF263692 Genomic DNA Translation: AAL01217.1
AF263693 Genomic DNA Translation: AAL01218.1
AF263694 Genomic DNA Translation: AAL01219.1
AF263695 Genomic DNA Translation: AAL01220.1
AF263696 Genomic DNA Translation: AAL01221.1
AF263697 Genomic DNA Translation: AAL01222.1
AF263698 Genomic DNA Translation: AAL01223.1
AF263699 Genomic DNA Translation: AAL01224.1
AF263700 Genomic DNA Translation: AAL01225.1
AF263701 Genomic DNA Translation: AAL01226.1
AF263702 Genomic DNA Translation: AAL01227.1
AF263703 Genomic DNA Translation: AAL01228.1
AF263704 Genomic DNA Translation: AAL01229.1
AF263705 Genomic DNA Translation: AAL01230.1
AF263706 Genomic DNA Translation: AAL01231.1
AF263707 Genomic DNA Translation: AAL01232.1
AF263708 Genomic DNA Translation: AAL01233.1
AF263709 Genomic DNA Translation: AAL01234.1
AF263710 Genomic DNA Translation: AAL01235.1
AF263711 Genomic DNA Translation: AAL01236.1
AF263712 Genomic DNA Translation: AAL01237.1
AF263713 Genomic DNA Translation: AAL01238.1
AF263714 Genomic DNA Translation: AAL01239.1
AF263715 Genomic DNA Translation: AAL01240.1
AF263718 Genomic DNA Translation: AAL01243.1
AF263719 Genomic DNA Translation: AAL01244.1
AF495524 mRNA Translation: AAM14620.1
AY519590 mRNA Translation: AAS10060.1
AP000371 Genomic DNA Translation: BAB02538.1
CP002686 Genomic DNA Translation: AEE77380.1
PIRiA39289 TVMUG1
RefSeqiNP_189430.1, NM_113708.2
UniGeneiAt.42881

Genome annotation databases

EnsemblPlantsiAT3G27920.1; AT3G27920.1; AT3G27920
GeneIDi822415
GrameneiAT3G27920.1; AT3G27920.1; AT3G27920
KEGGiath:AT3G27920

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiGL1_ARATH
AccessioniPrimary (citable) accession number: P27900
Secondary accession number(s): Q39109
, Q53YQ0, Q93V34, Q93VW0, Q93WP0, Q947R6, Q9LF81, Q9LF82, Q9ST42
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: October 18, 2001
Last modified: April 25, 2018
This is version 155 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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