##gff-version 3
P27786	UniProtKB	Chain	1	507	.	.	.	ID=PRO_0000051935;Note=Steroid 17-alpha-hydroxylase/17%2C20 lyase	
P27786	UniProtKB	Binding site	441	441	.	.	.	Note=Axial binding residue;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P27786	UniProtKB	Mutagenesis	346	346	.	.	.	Note=49%25 and 41%25 of wild-type 17alpha-hydroxylase activity with progesterone and pregnenolone respectively. 36%25 and 27%25 of wild type 17%2C20-lyase activity with 17alpha-hydroxyprogesterone and 17alpha-hydroxypregnenolone respectively. R->H;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:36640554;Dbxref=PMID:36640554	
P27786	UniProtKB	Mutagenesis	357	357	.	.	.	Note=68%25 and 45%25 of wild-type 17alpha-hydroxylase activity with progesterone and pregnenolone respectively. 64%25 of wild type 17%2C20-lyase activity with 17alpha-hydroxyprogesterone. R->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:36640554;Dbxref=PMID:36640554