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Protein

Pupal cuticle protein Edg-78E

Gene

Edg78E

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Component of the cuticle of the pupa of fruit fly.

Miscellaneous

The sequence shown is from genomic DNA.

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Pupal cuticle protein Edg-78E
Gene namesi
Name:Edg78E
Synonyms:EDG-78E
ORF Names:CG7673
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0000551. Edg78E.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cuticle

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Sequence analysisAdd BLAST16
ChainiPRO_000000639917 – 122Pupal cuticle protein Edg-78EAdd BLAST106

Proteomic databases

PaxDbiP27779.
PRIDEiP27779.

Expressioni

Tissue specificityi

Imaginal (anterior) epidermis.

Gene expression databases

BgeeiFBgn0000551.
ExpressionAtlasiP27779. differential.
GenevisibleiP27779. DM.

Interactioni

Protein-protein interaction databases

BioGridi65602. 1 interactor.
DIPiDIP-19035N.
IntActiP27779. 1 interactor.
MINTiMINT-996798.
STRINGi7227.FBpp0078062.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 96Chitin-binding type R&RPROSITE-ProRule annotationAdd BLAST61

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410J25C. Eukaryota.
ENOG410YR66. LUCA.
InParanoidiP27779.
OMAiSFQNDAS.
OrthoDBiEOG091G0KRD.
PhylomeDBiP27779.

Family and domain databases

InterProiView protein in InterPro
IPR031311. CHIT_BIND_RR_consensus.
IPR000618. Insect_cuticle.
PfamiView protein in Pfam
PF00379. Chitin_bind_4. 1 hit.
PRINTSiPR00947. CUTICLE.
PROSITEiView protein in PROSITE
PS00233. CHIT_BIND_RR_1. 1 hit.
PS51155. CHIT_BIND_RR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P27779-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYKYLFCLAL IGCACADNIN KDAQIRSFQN DATDAEGNYQ YAYETSNGIQ
60 70 80 90 100
IQEAGNANGA RGAVAYVSPE GEHISLTYTA DEEGYHPVGD HLPTPPPVPA
110 120
YVLRALEYIR THPPAPAQKE QQ
Length:122
Mass (Da):13,347
Last modified:August 1, 1992 - v1
Checksum:iCD68BC35B62F78E0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M71247 Genomic DNA. Translation: AAA28499.1.
M71248 mRNA. Translation: AAA28500.1.
AE014296 Genomic DNA. Translation: AAF51702.1.
PIRiA49773.
RefSeqiNP_001287140.1. NM_001300211.1.
NP_524198.1. NM_079474.3.
UniGeneiDm.2506.

Genome annotation databases

EnsemblMetazoaiFBtr0078408; FBpp0078062; FBgn0000551.
FBtr0344634; FBpp0310951; FBgn0000551.
GeneIDi40354.
KEGGidme:Dmel_CG7673.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiCUP7_DROME
AccessioniPrimary (citable) accession number: P27779
Secondary accession number(s): Q9VP54
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: June 7, 2017
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase