Reviewed,
UniProtKB/Swiss-Prot P27761 (MPA13_AMBAR)
Last modified
April 14, 2009.
Version 54.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Pollen allergen Amb a 1.3 Alternative name(s): Antigen Amb a I Antigen E Short name=AgE Allergen=Amb a 1.3 |
| Organism | Ambrosia artemisiifolia (Short ragweed) |
| Taxonomic identifier | 4212 [NCBI] |
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › campanulids › Asterales › Asteraceae › Asteroideae › Heliantheae › Ambrosia |
Protein attributes
| Sequence length | 397 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Subunit structure | Monomer. |
| Tissue specificity | Pollen and flowers. |
| Post-translational modification | The N-terminus is blocked. |
| Allergenic properties | Causes an allergic reaction in human. This is one of the major allergens of the ragweed pollen. Ref.1 |
| Sequence similarities | Belongs to the polysaccharide lyase 1 family. Amb a subfamily. |
Ontologies
| Keywords | |
|---|---|
| Coding sequence diversity | Polymorphism |
| Disease | Allergen |
| Domain | Signal |
| PTM | Disulfide bond |
| Gene Ontology (GO) | |
| None. [Check GOA] | |
Sequence annotation (Features)
Sequences
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References
| [1] | "Cloning of Amb a I (antigen E), the major allergen family of short ragweed pollen." Rafnar T., Griffith I.J., Kuo M.-C., Bond J.F., Rogers B.L., Klapper D.G. J. Biol. Chem. 266:1229-1236(1991) [PubMed: 1702434] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], ALLERGENICITY. Tissue: Pollen. |
| [2] | "Sequence polymorphism of Amb a I and Amb a II, the major allergens in Ambrosia artemisiifolia (short ragweed)." Griffith I.J., Pollock J., Klapper D.G., Rogers B.L., Nault A.K. Int. Arch. Allergy Appl. Immunol. 96:296-304(1991) [PubMed: 1809687] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], VARIANTS. Tissue: Pollen. |
Cross-references
Sequence databases | |
|---|---|
| M62961 mRNA. Translation: AAA32668.1. M80560 mRNA. Translation: AAA32669.1. Sequence problems. | |
| PIR | C39099. C53240. |
3D structure databases | |
| ModBase | Search... |
Protein family/group databases | |
| CAZy | PL1. Polysaccharide Lyase Family 1. |
Family and domain databases | |
| InterPro | IPR002022. Amb_allergen. IPR018082. AmbAllergen. IPR012334. Pectin_lyas_fold. [Graphical view] |
| Gene3D | G3DSA:2.160.20.10. Pectin_lyas_fold. 1 hit. |
| Pfam | PF00544. Pec_lyase_C. 1 hit. [Graphical view] |
| PRINTS | PR00807. AMBALLERGEN. |
| SMART | SM00656. Amb_all. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | MPA13_AMBAR | ||||||||
| Accession | Primary (citable) accession number: P27761 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||
Relevant documents
| Allergens Nomenclature of allergens and list of entries |
| SIMILARITY comments Index of protein domains and families |

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