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Protein

Non-structural protein 3

Gene
N/A
Organism
Rotavirus C (strain RVC/Pig/United States/Cowden/1980) (RV-C)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May play a role in stimulating the translation of viral mRNAs.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-binding
Biological processTranslation regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Non-structural protein 3UniRule annotation
Short name:
NSP3UniRule annotation
Alternative name(s):
NCVP4UniRule annotation
Non-structural RNA-binding protein 34UniRule annotation
Short name:
NS34UniRule annotation
Cleaved into the following 2 chains:
OrganismiRotavirus C (strain RVC/Pig/United States/Cowden/1980) (RV-C)
Taxonomic identifieri10916 [NCBI]
Taxonomic lineageiVirusesdsRNA virusesReoviridaeSedoreovirinaeRotavirus
Virus hostiSus scrofa (Pig) [TaxID: 9823]
Proteomesi
  • UP000008175 Componenti: Genome

Subcellular locationi

  • Host cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Host cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001495441 – 402Non-structural protein 3Add BLAST402
ChainiPRO_00003698881 – 333p38Add BLAST333
ChainiPRO_0000369889334 – 402p8Add BLAST69

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei333 – 334Cleavage; by autolysisSequence analysis2

Structurei

3D structure databases

ProteinModelPortaliP27586
SMRiP27586
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini334 – 402DRBMPROSITE-ProRule annotationAdd BLAST69

Sequence similaritiesi

Belongs to the rotavirus NSP3 family.UniRule annotation

Phylogenomic databases

OrthoDBiVOG0900009V

Family and domain databases

HAMAPiMF_04090 ROTA_NSP3, 1 hit
InterProiView protein in InterPro
IPR014720 dsRBD_dom
IPR036082 NSP3_sf
IPR002873 Rotavirus_NSP3
PfamiView protein in Pfam
PF01665 Rota_NSP3, 1 hit
SUPFAMiSSF69903 SSF69903, 1 hit
PROSITEiView protein in PROSITE
PS50137 DS_RBD, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P27586-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATQASVEWI FNIAGSAASA SIAKAIKDAG GSEDFAKYVI ARFYDNYKDS
60 70 80 90 100
VDDTGVYNAC IGRARTVDKA LDDSRKAERN EDWHTNLETI SRLDLELAEL
110 120 130 140 150
KLILSNLGIK REDRVLNSMF SVVREEGKSS NTVMLKQNAV RMIEEGKLKI
160 170 180 190 200
RVERNENYTA SLKNKIEELE CMIDAFEKGK EIIISLDAMN GEVKRDGNSC
210 220 230 240 250
SYNSTAAFVS TIVGNPIKMY DESGKPLFDV GDYLNPKHII DKMIENEIPI
260 270 280 290 300
FKSDYRNNES PDFDVWNERS NLKIVSINDC HAICVFKFEN AWWCFDDGVL
310 320 330 340 350
NKYSGNGNPL IVANAKFQID KILISGDVEL NPGPDPLIRL NDCKTKYGID
360 370 380 390 400
IICRFYIVLD NDGSIIHMCY MRTGSAEAVA KGRSKKEAKR IAAKDILDQI

GL
Length:402
Mass (Da):45,125
Last modified:August 1, 1992 - v1
Checksum:i8B11F7AC7FB5135C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M69115 Genomic RNA Translation: AAA47087.1
PIRiA41040 MNXRPC

Similar proteinsi

Entry informationi

Entry nameiNSP3_ROTPC
AccessioniPrimary (citable) accession number: P27586
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: April 25, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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