P27583 (FABG_PERAE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: 3-oxoacyl-[acyl-carrier-protein] reductase EC=1.1.1.100 Alternative name(s): 3-ketoacyl-acyl carrier protein reductase
Organism	Persea americana (Avocado)
Taxonomic identifier	3435 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › magnoliids › Laurales › Lauraceae › Persea

Protein attributes

Sequence length	106 AA.
Sequence status	Fragments.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP+ = 3-oxoacyl-[acyl-carrier-protein] + NADPH.
Pathway	Lipid metabolism; fatty acid biosynthesis.
Subunit structure	Homotetramer Probable.
Subcellular location	Plastid › chloroplast. Plastid. Note: And non-photosynthetic plastids.
Tissue specificity	Mesocarp.
Miscellaneous	Exhibits a marked preference for acyl-carrier protein derivatives over CoA derivatives as substrates.
Sequence similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Ontologies

Keywords
Biological process	Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism
Cellular component	Chloroplast Plastid
Ligand	NADP
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological_process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	chloroplast Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›106	›106	3-oxoacyl-[acyl-carrier-protein] reductase		PRO_0000054662
Experimental info
	Non-adjacent residues	24 – 25	2
	Non-adjacent residues	42 – 43	2
	Non-adjacent residues	51 – 52	2
	Non-adjacent residues	70 – 71	2
	Non-adjacent residues	78 – 79	2
	Non-adjacent residues	97 – 98	2
	Non-terminal residue	106	1

Sequences

	Sequence		Length	Mass (Da)
	P27583 [UniParc]. Last modified February 1, 1994. Version 3. Checksum: 3E9CD3B43FD90CC7	FASTA	106	11,084
	10 20 30 40 50 60 VYEQVSIEVP QSVEAPVVII TGASEIEAST IQALSFGPDV XKEADVEAMI KAVDAWGQVD 70 80 90 100 VLINNAGITR AGVIGLQKNI NVNAIAPGFI ASDMTAKILE TIPLGR

References

[1]	"3-oxoacyl-(acyl-carrier protein) reductase from avocado (Persea americana) fruit mesocarp." Sheldon P.S., Kekwick R.G.O., Sidebottom C.M., Smith C.G., Slabas A.R. Biochem. J. 271:713-720(1990) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE. Strain: cv. Fuerte. Tissue: Mesocarp.

Cross-references

Sequence databases
PIR	S13055.
3D structure databases
ProteinModelPortal	P27583.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
UniPathway	UPA00094.
Family and domain databases
Gene3D	3.40.50.720. 1 hit.
InterPro	IPR002198. DH_sc/Rdtase_SDR. IPR016040. NAD(P)-bd_dom. [Graphical view]
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PROSITE	PS00061. ADH_SHORT. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FABG_PERAE

Accession

Primary (citable) accession number: P27583

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1992
Last sequence update:	February 1, 1994
Last modified:	April 3, 2013
This is version 78 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program