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P27583 (FABG_PERAE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
3-oxoacyl-[acyl-carrier-protein] reductase

EC=1.1.1.100
Alternative name(s):
3-ketoacyl-acyl carrier protein reductase
OrganismPersea americana (Avocado)
Taxonomic identifier3435 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaMagnoliidaeLauralesLauraceaePersea

Protein attributes

Sequence length106 AA.
Sequence statusFragments.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP+ = 3-oxoacyl-[acyl-carrier-protein] + NADPH.

Pathway

Lipid metabolism; fatty acid biosynthesis.

Subunit structure

Homotetramer Probable.

Subcellular location

Plastidchloroplast. Plastid. Note: And non-photosynthetic plastids.

Tissue specificity

Mesocarp.

Miscellaneous

Exhibits a marked preference for acyl-carrier protein derivatives over CoA derivatives as substrates.

Sequence similarities

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Ontologies

Keywords
   Biological processFatty acid biosynthesis
Fatty acid metabolism
Lipid biosynthesis
Lipid metabolism
   Cellular componentChloroplast
Plastid
   LigandNADP
   Molecular functionOxidoreductase
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Biological_processfatty acid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentchloroplast

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_function3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – ›106›1063-oxoacyl-[acyl-carrier-protein] reductase
PRO_0000054662

Experimental info

Non-adjacent residues24 – 252
Non-adjacent residues42 – 432
Non-adjacent residues51 – 522
Non-adjacent residues70 – 712
Non-adjacent residues78 – 792
Non-adjacent residues97 – 982
Non-terminal residue1061

Sequences

Sequence LengthMass (Da)Tools
P27583 [UniParc].

Last modified February 1, 1994. Version 3.
Checksum: 3E9CD3B43FD90CC7

FASTA10611,084
        10         20         30         40         50         60 
VYEQVSIEVP QSVEAPVVII TGASEIEAST IQALSFGPDV XKEADVEAMI KAVDAWGQVD 

        70         80         90        100 
VLINNAGITR AGVIGLQKNI NVNAIAPGFI ASDMTAKILE TIPLGR 

« Hide

References

[1]"3-oxoacyl-(acyl-carrier protein) reductase from avocado (Persea americana) fruit mesocarp."
Sheldon P.S., Kekwick R.G.O., Sidebottom C.M., Smith C.G., Slabas A.R.
Biochem. J. 271:713-720(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE.
Strain: cv. Fuerte.
Tissue: Mesocarp.

Cross-references

Sequence databases

PIRS13055.

3D structure databases

ProteinModelPortalP27583.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00094.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
InterProIPR002198. DH_sc/Rdtase_SDR.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF00106. adh_short. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFABG_PERAE
AccessionPrimary (citable) accession number: P27583
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: February 1, 1994
Last modified: February 19, 2014
This is version 82 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways