Reviewed, UniProtKB/Swiss-Prot P27583 (FABG_PERAE)

Names and origin

Protein names	Recommended name:     3-oxoacyl-[acyl-carrier-protein] reductase     EC=1.1.1.100 Alternative name(s):     3-ketoacyl-acyl carrier protein reductase
Organism	Persea americana (Avocado)
Taxonomic identifier	3435 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › magnoliids › Laurales › Lauraceae › Persea

Protein attributes

Sequence length	106 AA.
Sequence status	Fragments.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP+ = 3-oxoacyl-[acyl-carrier-protein] + NADPH.
Pathway	Lipid metabolism; fatty acid biosynthesis.
Subunit structure	Homotetramer Probable.
Subcellular location	Plastid › chloroplast. Plastid. Note: And non-photosynthetic plastids.
Tissue specificity	Mesocarp.
Miscellaneous	Exhibits a marked preference for acyl-carrier protein derivatives over CoA derivatives as substrates.
Sequence similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Ontologies

Keywords
Biological process	Fatty acid biosynthesis Lipid synthesis
Cellular component	Chloroplast Plastid
Ligand	NADP
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	chloroplast Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-oxoacyl-[acyl-carrier-protein] reductase activity Inferred from electronic annotation. Source: EC binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›106	›106	3-oxoacyl-[acyl-carrier-protein] reductase		PRO_0000054662
Experimental info
	Non-adjacent residues	24 – 25	2
	Non-adjacent residues	42 – 43	2
	Non-adjacent residues	51 – 52	2
	Non-adjacent residues	70 – 71	2
	Non-adjacent residues	78 – 79	2
	Non-adjacent residues	97 – 98	2
	Non-terminal residue	106	1

Sequences

	Sequence		Length	Mass (Da)
	P27583-1 [UniParc]. Last modified February 1, 1994. Version 3. Checksum: 3E9CD3B43FD90CC7	FASTA	106	11,084
	10 20 30 40 50 60 VYEQVSIEVP QSVEAPVVII TGASEIEAST IQALSFGPDV XKEADVEAMI KAVDAWGQVD 70 80 90 100 VLINNAGITR AGVIGLQKNI NVNAIAPGFI ASDMTAKILE TIPLGR

References

[1]	"3-oxoacyl-(acyl-carrier protein) reductase from avocado (Persea americana) fruit mesocarp." Sheldon P.S., Kekwick R.G.O., Sidebottom C.M., Smith C.G., Slabas A.R. Biochem. J. 271:713-720(1990) [PubMed: 2244875] [Abstract] Cited for: PROTEIN SEQUENCE. Strain: cv. Fuerte. Tissue: Mesocarp.

Cross-references

Sequence databases
PIR	S13055.
3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	1.1.1.100. 2559.
Family and domain databases
InterPro	IPR002198. DH_sc/Rdtase_SDR. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PANTHER	PTHR19410. ADH_short_C2. 1 hit.
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PROSITE	PS00061. ADH_SHORT. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FABG_PERAE

Accession

Primary (citable) accession number: P27583

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1992
Last sequence update:	February 1, 1994
Last modified:	June 16, 2009
This is version 62 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)