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Protein

3-oxoacyl-[acyl-carrier-protein] reductase

Gene
N/A
Organism
Persea americana (Avocado)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP+ = 3-oxoacyl-[acyl-carrier-protein] + NADPH.

Pathway: fatty acid biosynthesis

This protein is involved in the pathway fatty acid biosynthesis, which is part of Lipid metabolism.
View all proteins of this organism that are known to be involved in the pathway fatty acid biosynthesis and in Lipid metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Keywords - Ligandi

NADP

Enzyme and pathway databases

UniPathwayiUPA00094.

Names & Taxonomyi

Protein namesi
Recommended name:
3-oxoacyl-[acyl-carrier-protein] reductase (EC:1.1.1.100)
Alternative name(s):
3-ketoacyl-acyl carrier protein reductase
OrganismiPersea americana (Avocado)
Taxonomic identifieri3435 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaMagnoliidaeLauralesLauraceaePersea

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – ›106›1063-oxoacyl-[acyl-carrier-protein] reductasePRO_0000054662Add
BLAST

Expressioni

Tissue specificityi

Mesocarp.

Interactioni

Subunit structurei

Homotetramer.Curated

Structurei

3D structure databases

ProteinModelPortaliP27583.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR002198. DH_sc/Rdtase_SDR.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragments.

P27583-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
VYEQVSIEVP QSVEAPVVII TGASEIEAST IQALSFGPDV XKEADVEAMI
60 70 80 90 100
KAVDAWGQVD VLINNAGITR AGVIGLQKNI NVNAIAPGFI ASDMTAKILE

TIPLGR
Length:106
Mass (Da):11,084
Last modified:February 1, 1994 - v3
Checksum:i3E9CD3B43FD90CC7
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-adjacent residuesi24 – 252Curated
Non-adjacent residuesi42 – 432Curated
Non-adjacent residuesi51 – 522Curated
Non-adjacent residuesi70 – 712Curated
Non-adjacent residuesi78 – 792Curated
Non-adjacent residuesi97 – 982Curated
Non-terminal residuei106 – 1061

Sequence databases

PIRiS13055.

Cross-referencesi

Sequence databases

PIRiS13055.

3D structure databases

ProteinModelPortaliP27583.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayiUPA00094.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR002198. DH_sc/Rdtase_SDR.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "3-oxoacyl-(acyl-carrier protein) reductase from avocado (Persea americana) fruit mesocarp."
    Sheldon P.S., Kekwick R.G.O., Sidebottom C.M., Smith C.G., Slabas A.R.
    Biochem. J. 271:713-720(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE.
    Strain: cv. Fuerte.
    Tissue: Mesocarp.

Entry informationi

Entry nameiFABG_PERAE
AccessioniPrimary (citable) accession number: P27583
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: February 1, 1994
Last modified: January 7, 2015
This is version 85 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Miscellaneous

Exhibits a marked preference for acyl-carrier protein derivatives over CoA derivatives as substrates.

Keywords - Technical termi

Direct protein sequencing

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.