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Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Acts as a chaperone.By similarity

Miscellaneous

Expressed early during infection.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processStress response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaK
Alternative name(s):
75 kDa membrane protein
HSP70
Heat shock 70 kDa protein
Heat shock protein 70
Gene namesi
Name:dnaK
Ordered Locus Names:CPn_0503, CP_0251, CpB0523
OrganismiChlamydia pneumoniae (Chlamydophila pneumoniae)
Taxonomic identifieri83558 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
Proteomesi
  • UP000000583 Componenti: Chromosome
  • UP000000801 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  • symbiont-containing vacuole Source: CAFA

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000784441 – 660Chaperone protein DnaKAdd BLAST660

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei201Phosphothreonine; by autocatalysisBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiP27542

Expressioni

Inductioni

By stress conditions e.g. heat shock (By similarity).By similarity

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi182082.CpB0523

Structurei

3D structure databases

ProteinModelPortaliP27542
SMRiP27542
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.Curated

Phylogenomic databases

eggNOGiENOG4105CFG Bacteria
COG0443 LUCA
HOGENOMiHOG000228135
KOiK04043
OMAiISIKRHM
OrthoDBiPOG091H01UE

Family and domain databases

Gene3Di1.20.1270.10, 1 hit
2.60.34.10, 1 hit
HAMAPiMF_00332 DnaK, 1 hit
InterProiView protein in InterPro
IPR012725 Chaperone_DnaK
IPR018181 Heat_shock_70_CS
IPR029048 HSP70_C_sf
IPR029047 HSP70_peptide-bd_sf
IPR013126 Hsp_70_fam
PANTHERiPTHR19375 PTHR19375, 1 hit
PfamiView protein in Pfam
PF00012 HSP70, 1 hit
PRINTSiPR00301 HEATSHOCK70
SUPFAMiSSF100920 SSF100920, 1 hit
SSF100934 SSF100934, 1 hit
TIGRFAMsiTIGR02350 prok_dnaK, 1 hit
PROSITEiView protein in PROSITE
PS00297 HSP70_1, 1 hit
PS00329 HSP70_2, 1 hit
PS01036 HSP70_3, 1 hit

Sequencei

Sequence statusi: Complete.

P27542-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEHKKSSKI IGIDLGTTNS CVSVMEGGQA KVITSSEGTR TTPSIVAFKG
60 70 80 90 100
NEKLVGIPAK RQAVTNPEKT LGSTKRFIGR KYSEVASEIQ TVPYTVTSGS
110 120 130 140 150
KGDAVFEVDG KQYTPEEIGA QILMKMKETA EAYLGETVTE AVITVPAYFN
160 170 180 190 200
DSQRASTKDA GRIAGLDVKR IIPEPTAAAL AYGIDKVGDK KIAVFDLGGG
210 220 230 240 250
TFDISILEIG DGVFEVLSTN GDTLLGGDDF DEVIIKWMIE EFKKQEGIDL
260 270 280 290 300
SKDNMALQRL KDAAEKAKIE LSGVSSTEIN QPFITMDAQG PKHLALTLTR
310 320 330 340 350
AQFEKLAASL IERTKSPCIK ALSDAKLSAK DIDDVLLVGG MSRMPAVQET
360 370 380 390 400
VKELFGKEPN KGVNPDEVVA IGAAIQGGVL GGEVKDVLLL DVIPLSLGIE
410 420 430 440 450
TLGGVMTTLV ERNTTIPTQK KQIFSTAADN QPAVTIVVLQ GERPMAKDNK
460 470 480 490 500
EIGRFDLTDI PPAPRGHPQI EVSFDIDANG IFHVSAKDVA SGKEQKIRIE
510 520 530 540 550
ASSGLQEDEI QRMVRDAEIN KEEDKKRREA SDAKNEADSM IFRAEKAIKD
560 570 580 590 600
YKEQIPETLV KEIEERIENV RNALKDDAPI EKIKEVTEDL SKHMQKIGES
610 620 630 640 650
MQSQSASAAA SSAANAKGGP NINTEDLKKH SFSTKPPSNN GSSEDHIEEA
660
DVEIIDNDDK
Length:660
Mass (Da):71,354
Last modified:August 1, 1992 - v1
Checksum:iE6EAF533557A3596
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M69227 Genomic DNA Translation: AAA23121.1
AE001363 Genomic DNA Translation: AAD18643.1
AE002161 Genomic DNA Translation: AAF38114.1
BA000008 Genomic DNA Translation: BAA98709.1
AE009440 Genomic DNA Translation: AAP98452.1
PIRiC86553
S16159
RefSeqiNP_224699.1, NC_000922.1
WP_010883141.1, NZ_LN847257.1

Genome annotation databases

EnsemblBacteriaiAAD18643; AAD18643; CPn_0503
AAF38114; AAF38114; CP_0251
AAP98452; AAP98452; CpB0523
BAA98709; BAA98709; BAA98709
GeneIDi894942
KEGGicpa:CP_0251
cpj:dnaK
cpn:CPn0503
cpt:CpB0523
PATRICifig|115713.3.peg.562

Similar proteinsi

Entry informationi

Entry nameiDNAK_CHLPN
AccessioniPrimary (citable) accession number: P27542
Secondary accession number(s): Q9JQ25
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: March 28, 2018
This is version 137 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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