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P27469 (G0S2_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
G0/G1 switch regulatory protein 2
Gene names
Name:G0S2
OrganismHomo sapiens (Human)
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length103 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Potential oncogene and regulator of latent HIV.

Ontologies

Keywords
   Biological processCell cycle
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processcell cycle

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 103103G0/G1 switch regulatory protein 2
PRO_0000087405

Sequences

Sequence LengthMass (Da)Tools
P27469 [UniParc].

Last modified August 1, 1992. Version 1.
Checksum: 0FA91951D419E75C

FASTA10311,321
        10         20         30         40         50         60 
METVQELIPL AKEMMAQKRK GKMVKLYVLG SVLALFGVVL GLMETVCSPF TAARRLRDQE 

        70         80         90        100 
AAVAELQAAL ERQALQKQAL QEKGKQQDTV LGGRALSNRQ HAS

« Hide

References

« Hide 'large scale' references
[1]"A human putative lymphocyte G0/G1 switch gene containing a CpG-rich island encodes a small basic protein with the potential to be phosphorylated."
Russell L., Forsdyke D.R.
DNA Cell Biol. 10:581-591(1991) [PubMed: 1930693] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. expand/collapse author list , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
Nature 441:315-321(2006) [PubMed: 16710414] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Lung.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		M72885 Genomic DNA. Translation: AAA58966.1.
M69199 Genomic DNA. Translation: AAB04044.1.
AL031316 Genomic DNA. Translation: CAB40150.1.
BC009694 mRNA. Translation: AAH09694.1.
IPIIPI00018915.
PIRA40409. B40409.
RefSeqNP_056529.1. NM_015714.3.
UniGeneHs.432132.

3D structure databases

ProteinModelPortalP27469.
ModBaseSearch...

Protein-protein interaction databases

IntActP27469. 1 interaction.
STRINGP27469.

Polymorphism databases

DMDM120624.

Proteomic databases

PeptideAtlasP27469.
PRIDEP27469.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000367029; ENSP00000355996; ENSG00000123689.
GeneID50486.
KEGGhsa:50486.
UCSCuc001hhi.2. human.

Organism-specific databases

CTD50486.
GeneCardsGC01P209848.
HGNCHGNC:30229. G0S2.
HPAHPA010016.
neXtProtNX_P27469.
PharmGKBPA142671707.
GenAtlasSearch...

Phylogenomic databases

eggNOGmaNOG21607.
HOGENOMHBG125901.
HOVERGENHBG004465.
InParanoidP27469.
OMAKELMAHK.
OrthoDBEOG42NJ24.
PhylomeDBP27469.

Gene expression databases

ArrayExpressP27469.
BgeeP27469.
CleanExHS_G0S2.
GenevestigatorP27469.
GermOnlineENSG00000123689. Homo sapiens.

Family and domain databases

InterProIPR016821. G0/G1_switch_2_put.
[Graphical view]
PIRSFPIRSF023925. G0/G1_switch_p2. 1 hit.
ProtoNetSearch...

Other

NextBio53044.

Entry information

Entry nameG0S2_HUMAN
AccessionPrimary (citable) accession number: P27469
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: January 25, 2012
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 1

Human chromosome 1: entries, gene names and cross-references to MIM

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents