P27459 (PRLA_ACHLY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Alpha-lytic protease EC=3.4.21.12 Alternative name(s): Alpha-lytic endopeptidase
Organism	Achromobacter lyticus
Taxonomic identifier	224 [NCBI]
Taxonomic lineage	Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Achromobacter

Protein attributes

Sequence length	25 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	Preferential cleavage: Ala-|-Xaa, Val-|-Xaa in bacterial cell walls, elastin and other proteins.
Sequence similarities	Belongs to the peptidase S1 family.

Ontologies

Keywords
Molecular function	Hydrolase Protease Serine protease
PTM	Zymogen
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	serine-type peptidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›25	›25	Alpha-lytic protease		PRO_0000093855
Experimental info
	Sequence uncertainty	17	1
	Non-terminal residue	25	1

Sequences

	Sequence		Length	Mass (Da)
	P27459 [UniParc]. Last modified August 1, 1992. Version 1. Checksum: 33F56B45BF81573E	FASTA	25	2,572
	10 20 ANIVGGIEYS INNASICSVG FSVTR

References

[1]	"Molecular cloning and nucleotide sequence of the beta-lytic protease gene from Achromobacter lyticus." Li S.L., Norioka S., Sakiyama F. J. Bacteriol. 172:6506-6511(1990) [PubMed: 2228973] [Abstract] Cited for: PROTEIN SEQUENCE. Strain: M497-1.
+	Additional computationally mapped references.

Cross-references

3D structure databases
ModBase	Search...
Protein family/group databases
MEROPS	S01.268.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
PROSITE	PS00134. TRYPSIN_HIS. Partial match. PS00135. TRYPSIN_SER. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PRLA_ACHLY

Accession

Primary (citable) accession number: P27459

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1992
Last sequence update:	August 1, 1992
Last modified:	November 16, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program