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Protein

Protein VP2

Gene

ORF2

Organism
Rabbit hemorrhagic disease virus (strain Rabbit/Germany/FRG/1989) (Ra/LV/RHDV/GH/1989/GE) (RHDV-FRG)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Minor structural protein present in one or two copies per virion. Does not seem to play a role in capsid assembly, but is essential for production of infectious virus (By similarity).By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Protein VP2
Alternative name(s):
Minor capsid protein
Gene namesi
ORF Names:ORF2
OrganismiRabbit hemorrhagic disease virus (strain Rabbit/Germany/FRG/1989) (Ra/LV/RHDV/GH/1989/GE) (RHDV-FRG)
Taxonomic identifieri314536 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageCaliciviridaeLagovirus
Virus hostiOryctolagus cuniculus (Rabbit) [TaxID: 9986]
ProteomesiUP000000413: Genome

Subcellular locationi

Virion. Host cytoplasm By similarity

GO - Cellular componenti

  1. host cell cytoplasm Source: UniProtKB-SubCell
  2. virion Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Host cytoplasm, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 117117Protein VP2PRO_0000100128Add
BLAST

Interactioni

Subunit structurei

May interact with capsid protein.By similarity

Family & Domainsi

Sequence similaritiesi

Belongs to the lagovirus VP2 protein family.Curated

Family and domain databases

InterProiIPR008558. Lagovirus_RHDV_Vp2.
[Graphical view]
PfamiPF05801. DUF840. 1 hit.
[Graphical view]
ProDomiPD009258. DUF840_lagovir. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

P27412-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAFLMSEFIG LGLAGAGVLS NALLRRQELQ LQKQAMENGL VLKADQLGRL
60 70 80 90 100
GFNPNEVKNV IVGNSFSSNV RLSNMHNDAS VVNAYNVYNP ASNGIRKKIK
110
SLNNSVKIYN TTGESSV
Length:117
Mass (Da):12,670
Last modified:August 1, 1992 - v1
Checksum:i838811B8CAB21C46
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M67473 Genomic RNA. Translation: AAA47286.1.
PIRiB41039. VCWWRH.
RefSeqiNP_062876.1. NC_001543.1.

Genome annotation databases

GeneIDi1491967.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M67473 Genomic RNA. Translation: AAA47286.1.
PIRiB41039. VCWWRH.
RefSeqiNP_062876.1. NC_001543.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1491967.

Family and domain databases

InterProiIPR008558. Lagovirus_RHDV_Vp2.
[Graphical view]
PfamiPF05801. DUF840. 1 hit.
[Graphical view]
ProDomiPD009258. DUF840_lagovir. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Publicationsi

  1. "Rabbit hemorrhagic disease virus -- molecular cloning and nucleotide sequencing of a calicivirus genome."
    Meyers G., Wirblich C., Thiel H.-J.
    Virology 184:664-676(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiVP2_RHDVF
AccessioniPrimary (citable) accession number: P27412
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: January 7, 2015
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Miscellaneous

Translated by a ribosomal terminaition-reinitiation process from the bicistronic mRNA coding for VP1 and VP2.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.