P27412 (VP2_RHDVF) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein VP2

Alternative name(s):
Minor capsid protein

Gene names

ORF Names:

ORF2

Organism

Rabbit hemorrhagic disease virus (strain Rabbit/Germany/FRG/1989) (Ra/LV/RHDV/GH/1989/GE) (RHDV-FRG) [Reference proteome]

Taxonomic identifier

314536 [NCBI]

Taxonomic lineage

Viruses › ssRNA viruses › ssRNA positive-strand viruses, no DNA stage › Caliciviridae › Lagovirus › Rabbit hemorrhagic disease virus

Virus host

Oryctolagus cuniculus (Rabbit) [TaxID: 9986]

Protein attributes

Sequence length	117 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Minor structural protein present in one or two copies per virion. Does not seem to play a role in capsid assembly, but is essential for production of infectious virus By similarity.
Subunit structure	May interact with capsid protein By similarity.
Subcellular location	Virion. Host cytoplasm By similarity.
Miscellaneous	Translated by a ribosomal terminaition-reinitiation process from the bicistronic mRNA coding for VP1 and VP2.
Sequence similarities	Belongs to the lagovirus VP2 protein family.

Ontologies

Keywords
Cellular component	Host cytoplasm Virion
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	host cell cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell virion Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 117	117	Protein VP2		PRO_0000100128

Sequences

	Sequence		Length	Mass (Da)
	P27412 [UniParc]. Last modified August 1, 1992. Version 1. Checksum: 838811B8CAB21C46	FASTA	117	12,670
	10 20 30 40 50 60 MAFLMSEFIG LGLAGAGVLS NALLRRQELQ LQKQAMENGL VLKADQLGRL GFNPNEVKNV 70 80 90 100 110 IVGNSFSSNV RLSNMHNDAS VVNAYNVYNP ASNGIRKKIK SLNNSVKIYN TTGESSV

References

[1]	"Rabbit hemorrhagic disease virus -- molecular cloning and nucleotide sequencing of a calicivirus genome." Meyers G., Wirblich C., Thiel H.-J. Virology 184:664-676(1991) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	M67473 Genomic RNA. Translation: AAA47286.1.
PIR	VCWWRH. B41039.
RefSeq	NP_062876.1. NC_001543.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1491967.
Family and domain databases
InterPro	IPR008558. Lagovirus_RHDV_Vp2. [Graphical view]
Pfam	PF05801. DUF840. 1 hit. [Graphical view]
ProDom	PD009258. DUF840_lagovir. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

VP2_RHDVF

Accession

Primary (citable) accession number: P27412

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1992
Last sequence update:	August 1, 1992
Last modified:	May 29, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program