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Protein

Heat shock protein C

Gene

htrC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Keywords - Biological processi

Stress response

Enzyme and pathway databases

BioCyciEcoCyc:EG11429-MONOMER.
ECOL316407:JW3952-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Heat shock protein C
Gene namesi
Name:htrC
Synonyms:yjaZ
Ordered Locus Names:b3989, JW3952
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11429. htrC.

Pathology & Biotechi

Disruption phenotypei

Cells lose the inability to form colonies at 42 degrees Celsius. At 43 degrees Celsius, htrC mutant bacteria gradually lyse, whereas at intermediate temperatures they filament extensively.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000840861 – 179Heat shock protein CAdd BLAST179

Proteomic databases

PaxDbiP27375.
PRIDEiP27375.

Interactioni

Protein-protein interaction databases

BioGridi4261333. 197 interactors.
STRINGi511145.b3989.

Structurei

3D structure databases

ProteinModelPortaliP27375.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410645W. Bacteria.
ENOG4112D5I. LUCA.
HOGENOMiHOG000009660.
OMAiKSIMTPT.

Sequencei

Sequence statusi: Complete.

P27375-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKQEVEKWRP FGHPDGDIRD LSFLDAHQAV YVQHHEGKEP LEYRFWVTYS
60 70 80 90 100
LHCFTKDYEH QTNEEKQSLM YHAPKESRPF CQHRYNLART HLKRTILALP
110 120 130 140 150
ESNVIHAGYG SYAVIEVDLD GGDKAFYFVA FRAFREKKKL RLHVTSAYPI
160 170
SEKQKGKSVK FFTIAYNLLR NKQLPQPSK
Length:179
Mass (Da):21,131
Last modified:August 1, 1992 - v1
Checksum:i1D30F612CD3DFF93
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00339 Genomic DNA. No translation available.
U00006 Genomic DNA. Translation: AAC43087.1.
U00096 Genomic DNA. Translation: AAC76963.1.
AP009048 Genomic DNA. Translation: BAE77331.1.
PIRiH65205.
RefSeqiNP_418416.1. NC_000913.3.
WP_001307500.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76963; AAC76963; b3989.
BAE77331; BAE77331; BAE77331.
GeneIDi948495.
KEGGiecj:JW3952.
eco:b3989.
PATRICi32123499. VBIEscCol129921_4102.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
V00339 Genomic DNA. No translation available.
U00006 Genomic DNA. Translation: AAC43087.1.
U00096 Genomic DNA. Translation: AAC76963.1.
AP009048 Genomic DNA. Translation: BAE77331.1.
PIRiH65205.
RefSeqiNP_418416.1. NC_000913.3.
WP_001307500.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP27375.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261333. 197 interactors.
STRINGi511145.b3989.

Proteomic databases

PaxDbiP27375.
PRIDEiP27375.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76963; AAC76963; b3989.
BAE77331; BAE77331; BAE77331.
GeneIDi948495.
KEGGiecj:JW3952.
eco:b3989.
PATRICi32123499. VBIEscCol129921_4102.

Organism-specific databases

EchoBASEiEB1399.
EcoGeneiEG11429. htrC.

Phylogenomic databases

eggNOGiENOG410645W. Bacteria.
ENOG4112D5I. LUCA.
HOGENOMiHOG000009660.
OMAiKSIMTPT.

Enzyme and pathway databases

BioCyciEcoCyc:EG11429-MONOMER.
ECOL316407:JW3952-MONOMER.

Miscellaneous databases

PROiP27375.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiHTRC_ECOLI
AccessioniPrimary (citable) accession number: P27375
Secondary accession number(s): Q2M8S5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: November 2, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.